PubMed

The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage.

Bekpen C, Hunn JP, Rohde C, Parvanova I, Guethlein L, Dunn DM, Glowalla E, Leptin M, Howard JC.

Genome Biol. 2005;6(11):R92. Epub 2005 Oct 31.PMID: 16277747 [PubMed - indexed for MEDLINE]Related articlesFree article

A giant GTPase, very large inducible GTPase-1, is inducible by IFNs.

Klamp T, Boehm U, Schenk D, Pfeffer K, Howard JC.

J Immunol. 2003 Aug 1;171(3):1255-65.PMID: 12874213 [PubMed - indexed for MEDLINE]Related articlesFree article

Crystal structure of IIGP1: a paradigm for interferon-inducible p47 resistance GTPases.

Ghosh A, Uthaiah R, Howard J, Herrmann C, Wolf E.

Mol Cell. 2004 Sep 10;15(5):727-39.PMID: 15350217 [PubMed - indexed for MEDLINE]Related articles

The evolutionarily dynamic IFN-inducible GTPase proteins play conserved immune functions in vertebrates and cephalochordates.

Li G, Zhang J, Sun Y, Wang H, Wang Y.

Mol Biol Evol. 2009 Jul;26(7):1619-30. Epub 2009 Apr 15.PMID: 19369598 [PubMed - indexed for MEDLINE]Related articles

IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens.

Taylor GA.

Cell Microbiol. 2007 May;9(5):1099-107. Epub 2007 Mar 13. Review.PMID: 17359233 [PubMed - indexed for MEDLINE]Related articles

IIGP1, an interferon-gamma-inducible 47-kDa GTPase of the mouse, showing cooperative enzymatic activity and GTP-dependent multimerization.

Uthaiah RC, Praefcke GJ, Howard JC, Herrmann C.

J Biol Chem. 2003 Aug 1;278(31):29336-43. Epub 2003 May 5.PMID: 12732635 [PubMed - indexed for MEDLINE]Related articlesFree article

Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases).

Taylor GA, Feng CG, Sher A.

Microbes Infect. 2007 Nov-Dec;9(14-15):1644-51. Epub 2007 Sep 14. Review.PMID: 18023232 [PubMed - indexed for MEDLINE]Related articles

IFN-inducible GTPases and immunity to intracellular pathogens.

MacMicking JD.

Trends Immunol. 2004 Nov;25(11):601-9. Review.PMID: 15489189 [PubMed - indexed for MEDLINE]Related articles

Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii.

Hunn JP, Koenen-Waisman S, Papic N, Schroeder N, Pawlowski N, Lange R, Kaiser F, Zerrahn J, Martens S, Howard JC.

EMBO J. 2008 Oct 8;27(19):2495-509. Epub 2008 Sep 4.PMID: 18772884 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparative genomics of the syndecans defines an ancestral genomic context associated with matrilins in vertebrates.

Chakravarti R, Adams JC.

BMC Genomics. 2006 Apr 18;7:83.PMID: 16620374 [PubMed - indexed for MEDLINE]Related articlesFree article

Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene family: tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes.

Harduin-Lepers A, Petit D, Mollicone R, Delannoy P, Petit JM, Oriol R.

BMC Evol Biol. 2008 Sep 23;8:258.PMID: 18811928 [PubMed - indexed for MEDLINE]Related articlesFree article

p47 GTPases: regulators of immunity to intracellular pathogens.

Taylor GA, Feng CG, Sher A.

Nat Rev Immunol. 2004 Feb;4(2):100-9. Review.PMID: 15040583 [PubMed - indexed for MEDLINE]Related articles

Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases.

Martens S, Parvanova I, Zerrahn J, Griffiths G, Schell G, Reichmann G, Howard JC.

PLoS Pathog. 2005 Nov;1(3):e24. Epub 2005 Nov 18.PMID: 16304607 [PubMed - indexed for MEDLINE]Related articlesFree article

Emerging themes in IFN-gamma-induced macrophage immunity by the p47 and p65 GTPase families.

Shenoy AR, Kim BH, Choi HP, Matsuzawa T, Tiwari S, MacMicking JD.

Immunobiology. 2007;212(9-10):771-84. Epub 2007 Nov 28. Review.PMID: 18086378 [PubMed - indexed for MEDLINE]Related articlesFree article

IFN-inducible p47 GTPases display differential responses to Schistosoma japonicum acute infection.

Chen X, Du X, Zhang M, Zhang D, Ji M, Wu G.

Cell Mol Immunol. 2010 Jan;7(1):69-76. Epub 2009 Dec 23.PMID: 20029464 [PubMed - indexed for MEDLINE]Related articles

Phylogenetic distribution of translational GTPases in bacteria.

Margus T, Remm M, Tenson T.

BMC Genomics. 2007 Jan 10;8:15.PMID: 17214893 [PubMed - indexed for MEDLINE]Related articlesFree article

Immune control of phagosomal bacteria by p47 GTPases.

MacMicking JD.

Curr Opin Microbiol. 2005 Feb;8(1):74-82. Review.PMID: 15694860 [PubMed - indexed for MEDLINE]Related articles

The interferon-inducible GTPases.

Martens S, Howard J.

Annu Rev Cell Dev Biol. 2006;22:559-89. Review.PMID: 16824009 [PubMed - indexed for MEDLINE]Related articles

The IRG proteins: a function in search of a mechanism.

Howard J.

Immunobiology. 2008;213(3-4):367-75. Epub 2007 Dec 31. Review.PMID: 18406381 [PubMed - indexed for MEDLINE]Related articles

The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice.

Bernstein-Hanley I, Coers J, Balsara ZR, Taylor GA, Starnbach MN, Dietrich WF.

Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14092-7. Epub 2006 Sep 7.PMID: 16959883 [PubMed - indexed for MEDLINE]Related articlesFree article