PubMed

Increasing the decrement in insulin secretion improves glucagon responses to hypoglycemia in advanced type 2 diabetes.

Israelian Z, Gosmanov NR, Szoke E, Schorr M, Bokhari S, Cryer PE, Gerich JE, Meyer C.

Diabetes Care. 2005 Nov;28(11):2691-6.PMID: 16249541 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of the decrement in intraislet insulin for the glucagon response to hypoglycemia in humans.

Gosmanov NR, Szoke E, Israelian Z, Smith T, Cryer PE, Gerich JE, Meyer C.

Diabetes Care. 2005 May;28(5):1124-31.PMID: 15855577 [PubMed - indexed for MEDLINE]Related articlesFree article

Intraislet hyperinsulinemia prevents the glucagon response to hypoglycemia despite an intact autonomic response.

Banarer S, McGregor VP, Cryer PE.

Diabetes. 2002 Apr;51(4):958-65.PMID: 11916913 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers.

Nauck MA, Heimesaat MM, Behle K, Holst JJ, Nauck MS, Ritzel R, Hüfner M, Schmiegel WH.

J Clin Endocrinol Metab. 2002 Mar;87(3):1239-46.PMID: 11889194 [PubMed - indexed for MEDLINE]Related articlesFree article

Multiple defects in counterregulation of hypoglycemia in modestly advanced type 2 diabetes mellitus.

Israelian Z, Szoke E, Woerle J, Bokhari S, Schorr M, Schwenke DC, Cryer PE, Gerich JE, Meyer C.

Metabolism. 2006 May;55(5):593-8.PMID: 16631434 [PubMed - indexed for MEDLINE]Related articles

Differential effects of acute and extended infusions of glucagon-like peptide-1 on first- and second-phase insulin secretion in diabetic and nondiabetic humans.

Quddusi S, Vahl TP, Hanson K, Prigeon RL, D'Alessio DA.

Diabetes Care. 2003 Mar;26(3):791-8.PMID: 12610039 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of glucagon secretion during insulin-induced hypoglycemia in man. Role of the beta cell and arterial hyperinsulinemia.

Bolli G, De Feo P, Perriello G, De Cosmo S, Compagnucci P, Santeusanio F, Brunetti P, Unger RH.

J Clin Invest. 1984 Apr;73(4):917-22.PMID: 6368593 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of the decrement in intraislet insulin plausibly explains loss of the glucagon response to hypoglycemia in insulin-deficient diabetes: documentation of the intraislet insulin hypothesis in humans.

Raju B, Cryer PE.

Diabetes. 2005 Mar;54(3):757-64.PMID: 15734853 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibitory effect of circulating insulin on glucagon secretion during hypoglycemia in type I diabetic patients.

Liu DT, Adamson UC, Lins PE, Kollind ME, Moberg EA, Andréasson K.

Diabetes Care. 1992 Jan;15(1):59-65.PMID: 1346593 [PubMed - indexed for MEDLINE]Related articles

Effects of glycemic control on protective responses against hypoglycemia in type 2 diabetes.

Korzon-Burakowska A, Hopkins D, Matyka K, Lomas J, Pernet A, Macdonald I, Amiel S.

Diabetes Care. 1998 Feb;21(2):283-90.PMID: 9539997 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of autonomic nerves and the adrenal medulla contributes to increased glucagon secretion during moderate insulin-induced hypoglycemia in women.

Havel PJ, Ahren B.

Diabetes. 1997 May;46(5):801-7.PMID: 9133547 [PubMed - indexed for MEDLINE]Related articles

The defective glucagon response from transplanted intrahepatic pancreatic islets during hypoglycemia is transplantation site-determined.

Gupta V, Wahoff DC, Rooney DP, Poitout V, Sutherland DE, Kendall DM, Robertson RP.

Diabetes. 1997 Jan;46(1):28-33.PMID: 8971077 [PubMed - indexed for MEDLINE]Related articles

The use of tolbutamide-induced hypoglycemia to examine the intraislet role of insulin in mediating glucagon release in normal humans.

Peacey SR, Rostami-Hodjegan A, George E, Tucker GT, Heller SR.

J Clin Endocrinol Metab. 1997 May;82(5):1458-61.PMID: 9141533 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of physiological hyperinsulinemia on counterregulatory hormone responses during hypoglycemia in humans.

Mellman MJ, Davis MR, Shamoon H.

J Clin Endocrinol Metab. 1992 Nov;75(5):1293-7.PMID: 1430091 [PubMed - indexed for MEDLINE]Related articles

Abnormal glucose counterregulation in insulin-dependent diabetes mellitus. Interaction of anti-insulin antibodies and impaired glucagon and epinephrine secretion.

Bolli G, de Feo P, Compagnucci P, Cartechini MG, Angeletti G, Santeusanio F, Brunetti P, Gerich JE.

Diabetes. 1983 Feb;32(2):134-41.PMID: 6337896 [PubMed - indexed for MEDLINE]Related articles

Hormonal and metabolic counterregulation during and after high-dose insulin-induced hypoglycemia in diabetes mellitus type 2.

Bischof MG, Ludwig C, Hofer A, Kletter K, Krebs M, Stingl H, Nowotny P, Waldhäusl W, Roden M.

Horm Metab Res. 2000 Oct;32(10):417-23.PMID: 11069207 [PubMed - indexed for MEDLINE]Related articles

Counterregulatory responses to hypoglycemia in patients with glucokinase gene mutations.

Guenat E, Seematter G, Philippe J, Temler E, Jequier E, Tappy L.

Diabetes Metab. 2000 Nov;26(5):377-84.PMID: 11119017 [PubMed - indexed for MEDLINE]Related articlesFree article

One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes.

Degn KB, Juhl CB, Sturis J, Jakobsen G, Brock B, Chandramouli V, Rungby J, Landau BR, Schmitz O.

Diabetes. 2004 May;53(5):1187-94.PMID: 15111485 [PubMed - indexed for MEDLINE]Related articlesFree article

Similar physiological and symptomatic responses to sulphonylurea and insulin induced hypoglycaemia in normal subjects.

Peacey SR, George E, Rostami-Hodjegan A, Bedford C, Harris N, Hardisty CA, Tucker GT, Macdonald IA, Heller SR.

Diabet Med. 1996 Jul;13(7):634-41.PMID: 8840097 [PubMed - indexed for MEDLINE]Related articles

Impaired beta-cell function, incretin effect, and glucagon suppression in patients with type 1 diabetes who have normal fasting glucose.

Greenbaum CJ, Prigeon RL, D'Alessio DA.

Diabetes. 2002 Apr;51(4):951-7.PMID: 11916912 [PubMed - indexed for MEDLINE]Related articlesFree article