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    Results: 1 to 20 of 235

    1.

    Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats.

    McCrimmon RJ, Evans ML, Fan X, McNay EC, Chan O, Ding Y, Zhu W, Gram DX, Sherwin RS.

    Diabetes. 2005 Nov;54(11):3169-74.PMID: 16249441 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Amplified hormonal counterregulatory responses to hypoglycemia in rats after systemic delivery of a SUR-1-selective K(+) channel opener?

    Fan X, Ding Y, Cheng H, Gram DX, Sherwin RS, McCrimmon RJ.

    Diabetes. 2008 Dec;57(12):3327-34. Epub 2008 Sep 5.PMID: 18776135 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses.

    Evans ML, McCrimmon RJ, Flanagan DE, Keshavarz T, Fan X, McNay EC, Jacob RJ, Sherwin RS.

    Diabetes. 2004 Oct;53(10):2542-51.PMID: 15448082 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    ATP-sensitive K(+) channels regulate the release of GABA in the ventromedial hypothalamus during hypoglycemia.

    Chan O, Lawson M, Zhu W, Beverly JL, Sherwin RS.

    Diabetes. 2007 Apr;56(4):1120-6. Epub 2007 Jan 24.PMID: 17251273 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Hypothalamic AMP-activated protein kinase activation with AICAR amplifies counterregulatory responses to hypoglycemia in a rodent model of type 1 diabetes.

    Fan X, Ding Y, Brown S, Zhou L, Shaw M, Vella MC, Cheng H, McNay EC, Sherwin RS, McCrimmon RJ.

    Am J Physiol Regul Integr Comp Physiol. 2009 Jun;296(6):R1702-8. Epub 2009 Apr 8.PMID: 19357294 [PubMed - indexed for MEDLINE]Related articles

    6.

    Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus.

    McCrimmon RJ, Fan X, Ding Y, Zhu W, Jacob RJ, Sherwin RS.

    Diabetes. 2004 Aug;53(8):1953-8.PMID: 15277372 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Activation of AMP-activated protein kinase within the ventromedial hypothalamus amplifies counterregulatory hormone responses in rats with defective counterregulation.

    McCrimmon RJ, Fan X, Cheng H, McNay E, Chan O, Shaw M, Ding Y, Zhu W, Sherwin RS.

    Diabetes. 2006 Jun;55(6):1755-60.PMID: 16731839 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Corticotrophin-releasing factor receptors within the ventromedial hypothalamus regulate hypoglycemia-induced hormonal counterregulation.

    McCrimmon RJ, Song Z, Cheng H, McNay EC, Weikart-Yeckel C, Fan X, Routh VH, Sherwin RS.

    J Clin Invest. 2006 Jun;116(6):1723-30.PMID: 16741581 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Caudal hindbrain lactate infusion alters glucokinase, SUR1, and neuronal substrate fuel transporter gene expression in the dorsal vagal complex, lateral hypothalamic area, and ventromedial nucleus hypothalamus of hypoglycemic male rats.

    Vavaiya KV, Briski KP.

    Brain Res. 2007 Oct 24;1176:62-70. Epub 2007 Aug 10.PMID: 17889836 [PubMed - indexed for MEDLINE]Related articles

    10.

    Blockade of GABA(A) receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia.

    Chan O, Zhu W, Ding Y, McCrimmon RJ, Sherwin RS.

    Diabetes. 2006 Apr;55(4):1080-7.PMID: 16567532 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia.

    McCrimmon RJ, Shaw M, Fan X, Cheng H, Ding Y, Vella MC, Zhou L, McNay EC, Sherwin RS.

    Diabetes. 2008 Feb;57(2):444-50. Epub 2007 Oct 31.PMID: 17977955 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Prior hypoglycemia enhances glucose responsiveness in some ventromedial hypothalamic glucosensing neurons.

    Kang L, Sanders NM, Dunn-Meynell AA, Gaspers LD, Routh VH, Thomas AP, Levin BE.

    Am J Physiol Regul Integr Comp Physiol. 2008 Mar;294(3):R784-92. Epub 2007 Dec 19.PMID: 18094065 [PubMed - indexed for MEDLINE]Related articles

    13.

    Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats.

    Borg MA, Sherwin RS, Borg WP, Tamborlane WV, Shulman GI.

    J Clin Invest. 1997 Jan 15;99(2):361-5.PMID: 9006005 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Type 1 corticotropin-releasing factor receptors in the ventromedial hypothalamus promote hypoglycemia-induced hormonal counterregulation.

    Cheng H, Zhou L, Zhu W, Wang A, Tang C, Chan O, Sherwin RS, McCrimmon RJ.

    Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E705-12. Epub 2007 Jun 19.PMID: 17578887 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Chronic hypoglycemia and diabetes impair counterregulation induced by localized 2-deoxy-glucose perfusion of the ventromedial hypothalamus in rats.

    Borg MA, Borg WP, Tamborlane WV, Brines ML, Shulman GI, Sherwin RS.

    Diabetes. 1999 Mar;48(3):584-7.PMID: 10078560 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation.

    Borg MA, Tamborlane WV, Shulman GI, Sherwin RS.

    Diabetes. 2003 Mar;52(3):663-6.PMID: 12606506 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Effects of differing durations of antecedent hypoglycemia on counterregulatory responses to subsequent hypoglycemia in normal humans.

    Davis SN, Mann S, Galassetti P, Neill RA, Tate D, Ertl AC, Costa F.

    Diabetes. 2000 Nov;49(11):1897-903.PMID: 11078457 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.

    Maedler K, Størling J, Sturis J, Zuellig RA, Spinas GA, Arkhammar PO, Mandrup-Poulsen T, Donath MY.

    Diabetes. 2004 Jul;53(7):1706-13.PMID: 15220194 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory responses after antecedent hypoglycemia.

    Chan O, Cheng H, Herzog R, Czyzyk D, Zhu W, Wang A, McCrimmon RJ, Seashore MR, Sherwin RS.

    Diabetes. 2008 May;57(5):1363-70. Epub 2008 Mar 28.PMID: 18375441 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia.

    Borg WP, During MJ, Sherwin RS, Borg MA, Brines ML, Shulman GI.

    J Clin Invest. 1994 Apr;93(4):1677-82.PMID: 8163668 [PubMed - indexed for MEDLINE]Related articlesFree article

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