PubMed

The human glomerular podocyte is a novel target for insulin action.

Coward RJ, Welsh GI, Yang J, Tasman C, Lennon R, Koziell A, Satchell S, Holman GD, Kerjaschki D, Tavaré JM, Mathieson PW, Saleem MA.

Diabetes. 2005 Nov;54(11):3095-102.PMID: 16249431 [PubMed - indexed for MEDLINE]Related articlesFree article

Thiazolidinediones ameliorate diabetic nephropathy via cell cycle-dependent mechanisms.

Okada T, Wada J, Hida K, Eguchi J, Hashimoto I, Baba M, Yasuhara A, Shikata K, Makino H.

Diabetes. 2006 Jun;55(6):1666-77.PMID: 16731829 [PubMed - indexed for MEDLINE]Related articlesFree article

Nephrin is critical for the action of insulin on human glomerular podocytes.

Coward RJ, Welsh GI, Koziell A, Hussain S, Lennon R, Ni L, Tavaré JM, Mathieson PW, Saleem MA.

Diabetes. 2007 Apr;56(4):1127-35.PMID: 17395751 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy.

Susztak K, Raff AC, Schiffer M, Böttinger EP.

Diabetes. 2006 Jan;55(1):225-33.PMID: 16380497 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin sensitivity and inhibition by forskolin, dipyridamole and pentobarbital of glucose transport in three L6 muscle cell lines.

Niu W, Bilan PJ, Hayashi M, Da Y, Yao Z.

Sci China C Life Sci. 2007 Dec;50(6):739-47. Epub 2007 Sep 20.PMID: 17882384 [PubMed - indexed for MEDLINE]Related articles

Regulation of glucose transporters by insulin and extracellular glucose in C2C12 myotubes.

Nedachi T, Kanzaki M.

Am J Physiol Endocrinol Metab. 2006 Oct;291(4):E817-28. Epub 2006 May 30.PMID: 16735448 [PubMed - indexed for MEDLINE]Related articlesFree article

BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury.

Mitu GM, Wang S, Hirschberg R.

Am J Physiol Renal Physiol. 2007 Nov;293(5):F1641-8. Epub 2007 Sep 5.PMID: 17804487 [PubMed - indexed for MEDLINE]Related articlesFree article

Ceramide- and oxidant-induced insulin resistance involve loss of insulin-dependent Rac-activation and actin remodeling in muscle cells.

JeBailey L, Wanono O, Niu W, Roessler J, Rudich A, Klip A.

Diabetes. 2007 Feb;56(2):394-403.PMID: 17259384 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of cortical actin filaments in insulin-resistant skeletal muscle cells impairs GLUT4 vesicle trafficking and glucose transport.

McCarthy AM, Spisak KO, Brozinick JT, Elmendorf JS.

Am J Physiol Cell Physiol. 2006 Nov;291(5):C860-8. Epub 2006 Jun 14.PMID: 16774991 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone enhances glucose uptake in glomerular podocytes using the glucose transporter GLUT1.

Lennon R, Welsh GI, Singh A, Satchell SC, Coward RJ, Tavaré JM, Mathieson PW, Saleem MA.

Diabetologia. 2009 Sep;52(9):1944-52. Epub 2009 Jun 17.PMID: 19533082 [PubMed - in process]Related articles

Insulin resistance, oxidative stress, and podocyte injury: role of rosuvastatin modulation of filtration barrier injury.

Whaley-Connell A, DeMarco VG, Lastra G, Manrique C, Nistala R, Cooper SA, Westerly B, Hayden MR, Wiedmeyer C, Wei Y, Sowers JR.

Am J Nephrol. 2008;28(1):67-75. Epub 2007 Oct 3.PMID: 17914247 [PubMed - indexed for MEDLINE]Related articles

Characterization of glucose uptake by cultured rat podocytes.

Lewko B, Bryl E, Witkowski JM, Latawiec E, Gołos M, Endlich N, Hähnel B, Koksch C, Angielski S, Kriz W, Stepinski J.

Kidney Blood Press Res. 2005;28(1):1-7. Epub 2004 Sep 20.PMID: 15383720 [PubMed - indexed for MEDLINE]Related articles

Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival.

Eremina V, Cui S, Gerber H, Ferrara N, Haigh J, Nagy A, Ema M, Rossant J, Jothy S, Miner JH, Quaggin SE.

J Am Soc Nephrol. 2006 Mar;17(3):724-35. Epub 2006 Jan 25.PMID: 16436493 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic exposure of human glomerular epithelial cells to high glucose concentration results in modulation of high-affinity glucose transporters expression.

Moutzouris DA, Kitsiou PV, Talamagas AA, Drossopoulou GI, Kassimatis TI, Katsilambros NK.

Ren Fail. 2007;29(3):353-8.PMID: 17497451 [PubMed - indexed for MEDLINE]Related articles

Functional role of sortilin in myogenesis and development of insulin-responsive glucose transport system in C2C12 myocytes.

Ariga M, Nedachi T, Katagiri H, Kanzaki M.

J Biol Chem. 2008 Apr 11;283(15):10208-20. Epub 2008 Feb 7.PMID: 18258592 [PubMed - indexed for MEDLINE]Related articlesFree article

Bone morphogenetic protein-7 delays podocyte injury due to high glucose.

De Petris L, Hruska KA, Chiechio S, Liapis H.

Nephrol Dial Transplant. 2007 Dec;22(12):3442-50. Epub 2007 Aug 8.PMID: 17686813 [PubMed - indexed for MEDLINE]Related articlesFree article

Hemopexin induces nephrin-dependent reorganization of the actin cytoskeleton in podocytes.

Lennon R, Singh A, Welsh GI, Coward RJ, Satchell S, Ni L, Mathieson PW, Bakker WW, Saleem MA.

J Am Soc Nephrol. 2008 Nov;19(11):2140-9. Epub 2008 Aug 27.PMID: 18753258 [PubMed - indexed for MEDLINE]Related articlesFree article

Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy.

Lennon R, Pons D, Sabin MA, Wei C, Shield JP, Coward RJ, Tavaré JM, Mathieson PW, Saleem MA, Welsh GI.

Nephrol Dial Transplant. 2009 Nov;24(11):3288-96. Epub 2009 Jun 25.PMID: 19556298 [PubMed - in process]Related articles

Permselective dysfunction of podocyte-podocyte contact upon angiotensin II unravels the molecular target for renoprotective intervention.

Macconi D, Abbate M, Morigi M, Angioletti S, Mister M, Buelli S, Bonomelli M, Mundel P, Endlich K, Remuzzi A, Remuzzi G.

Am J Pathol. 2006 Apr;168(4):1073-85.PMID: 16565484 [PubMed - indexed for MEDLINE]Related articlesFree article

Failure to phosphorylate AKT in podocytes from mice with early diabetic nephropathy promotes cell death.

Tejada T, Catanuto P, Ijaz A, Santos JV, Xia X, Sanchez P, Sanabria N, Lenz O, Elliot SJ, Fornoni A.

Kidney Int. 2008 Jun;73(12):1385-93. Epub 2008 Apr 2.PMID: 18385666 [PubMed - indexed for MEDLINE]Related articles