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Targeting energy metabolism in brain cancer: review and hypothesis.

Seyfried TN, Mukherjee P.

Nutr Metab (Lond). 2005 Oct 21;2:30.PMID: 16242042 [PubMed]Related articlesFree article

The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer.

Zhou W, Mukherjee P, Kiebish MA, Markis WT, Mantis JG, Seyfried TN.

Nutr Metab (Lond). 2007 Feb 21;4:5.PMID: 17313687 [PubMed]Related articlesFree article

Perspectives on the metabolic management of epilepsy through dietary reduction of glucose and elevation of ketone bodies.

Greene AE, Todorova MT, Seyfried TN.

J Neurochem. 2003 Aug;86(3):529-37. Review.PMID: 12859666 [PubMed - indexed for MEDLINE]Related articles

Role of glucose and ketone bodies in the metabolic control of experimental brain cancer.

Seyfried TN, Sanderson TM, El-Abbadi MM, McGowan R, Mukherjee P.

Br J Cancer. 2003 Oct 6;89(7):1375-82.PMID: 14520474 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeting energy metabolism in brain cancer with calorically restricted ketogenic diets.

Seyfried TN, Kiebish M, Mukherjee P, Marsh J.

Epilepsia. 2008 Nov;49 Suppl 8:114-6. Review.PMID: 19049606 [PubMed - indexed for MEDLINE]Related articles

Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet.

Marsh J, Mukherjee P, Seyfried TN.

Nutr Metab (Lond). 2008 Nov 25;5:33.PMID: 19032781 [PubMed - in process]Related articlesFree article

Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells.

Wu M, Neilson A, Swift AL, Moran R, Tamagnine J, Parslow D, Armistead S, Lemire K, Orrell J, Teich J, Chomicz S, Ferrick DA.

Am J Physiol Cell Physiol. 2007 Jan;292(1):C125-36. Epub 2006 Sep 13.PMID: 16971499 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain.

Mukherjee P, Mulrooney TJ, Marsh J, Blair D, Chiles TC, Seyfried TN.

Mol Cancer. 2008 May 12;7:37.PMID: 18474106 [PubMed - indexed for MEDLINE]Related articlesFree article

Adaptation of energy metabolism in breast cancer brain metastases.

Chen EI, Hewel J, Krueger JS, Tiraby C, Weber MR, Kralli A, Becker K, Yates JR 3rd, Felding-Habermann B.

Cancer Res. 2007 Feb 15;67(4):1472-86.PMID: 17308085 [PubMed - indexed for MEDLINE]Related articlesFree article

Antioxidant capacity contributes to protection of ketone bodies against oxidative damage induced during hypoglycemic conditions.

Haces ML, Hernández-Fonseca K, Medina-Campos ON, Montiel T, Pedraza-Chaverri J, Massieu L.

Exp Neurol. 2008 May;211(1):85-96. Epub 2008 Jan 26.PMID: 18339375 [PubMed - indexed for MEDLINE]Related articles

Brain uptake and metabolism of ketone bodies in animal models.

Nehlig A.

Prostaglandins Leukot Essent Fatty Acids. 2004 Mar;70(3):265-75. Review.PMID: 14769485 [PubMed - indexed for MEDLINE]Related articles

The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots.

Costello LC, Franklin RB.

Mol Cancer. 2006 May 15;5:17. Review.PMID: 16700911 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuronal-glial interactions in rats fed a ketogenic diet.

Melø TM, Nehlig A, Sonnewald U.

Neurochem Int. 2006 May-Jun;48(6-7):498-507. Epub 2006 Mar 20.PMID: 16542760 [PubMed - indexed for MEDLINE]Related articles

The neuropharmacology of the ketogenic diet.

Hartman AL, Gasior M, Vining EP, Rogawski MA.

Pediatr Neurol. 2007 May;36(5):281-92. Review.PMID: 17509459 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial UCP4 mediates an adaptive shift in energy metabolism and increases the resistance of neurons to metabolic and oxidative stress.

Liu D, Chan SL, de Souza-Pinto NC, Slevin JR, Wersto RP, Zhan M, Mustafa K, de Cabo R, Mattson MP.

Neuromolecular Med. 2006;8(3):389-414.PMID: 16775390 [PubMed - indexed for MEDLINE]Related articles

Hypoxic regulation of glucose transport, anaerobic metabolism and angiogenesis in cancer: novel pathways and targets for anticancer therapeutics.

Airley RE, Mobasheri A.

Chemotherapy. 2007;53(4):233-56. Epub 2007 Jun 25. Review.PMID: 17595539 [PubMed - indexed for MEDLINE]Related articles

Anticonvulsant mechanisms of the ketogenic diet.

Bough KJ, Rho JM.

Epilepsia. 2007 Jan;48(1):43-58. Review.PMID: 17241207 [PubMed - indexed for MEDLINE]Related articles

The ketogenic diet and epilepsy.

Kim do Y, Rho JM.

Curr Opin Clin Nutr Metab Care. 2008 Mar;11(2):113-20. Review.PMID: 18301085 [PubMed - indexed for MEDLINE]Related articles

Ketogenic diet metabolites reduce firing in central neurons by opening K(ATP) channels.

Ma W, Berg J, Yellen G.

J Neurosci. 2007 Apr 4;27(14):3618-25.PMID: 17409226 [PubMed - indexed for MEDLINE]Related articlesFree article

Cerebral metabolic adaptation and ketone metabolism after brain injury.

Prins ML.

J Cereb Blood Flow Metab. 2008 Jan;28(1):1-16. Epub 2007 Aug 8. Review.PMID: 17684514 [PubMed - indexed for MEDLINE]Related articles