PubMed

A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites.

Rose CS, Ek J, Urhammer SA, Glümer C, Borch-Johnsen K, Jørgensen T, Pedersen O, Hansen T.

Diabetes. 2005 Oct;54(10):3026-31.PMID: 16186409 [PubMed - indexed for MEDLINE]Related articlesFree article

The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population.

Vaxillaire M, Cavalcanti-Proença C, Dechaume A, Tichet J, Marre M, Balkau B, Froguel P; DESIR Study Group.

Diabetes. 2008 Aug;57(8):2253-7. Epub 2008 Jun 12.PMID: 18556336 [PubMed - indexed for MEDLINE]Related articlesFree article

A -243A-->G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects.

Boesgaard TW, Castella SI, Andersen G, Albrechtsen A, Sparsø T, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabet Med. 2007 Jul;24(7):702-6. Epub 2007 Apr 24.PMID: 17459095 [PubMed - indexed for MEDLINE]Related articles

A variation at position -30 of the beta-cell glucokinase gene promoter is associated with reduced beta-cell function in middle-aged Japanese-American men.

Stone LM, Kahn SE, Fujimoto WY, Deeb SS, Porte D Jr.

Diabetes. 1996 Apr;45(4):422-8.PMID: 8603762 [PubMed - indexed for MEDLINE]Related articles

Genetic regulation of birth weight and fasting glucose by a common polymorphism in the islet cell promoter of the glucokinase gene.

Weedon MN, Frayling TM, Shields B, Knight B, Turner T, Metcalf BS, Voss L, Wilkin TJ, McCarthy A, Ben-Shlomo Y, Davey Smith G, Ring S, Jones R, Golding J, Byberg L, Mann V, Axelsson T, Syvänen AC, Leon D, Hattersley AT.

Diabetes. 2005 Feb;54(2):576-81.PMID: 15677518 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical characteristics of Japanese men with glucokinase gene beta-cell promoter variant.

Yamada K, Yuan X, Ishiyama S, Ichikawa F, Koyama KI, Koyanagi A, Koyama W, Nonaka K.

Diabetes Care. 1997 Jul;20(7):1159-61.PMID: 9203455 [PubMed - indexed for MEDLINE]Related articles

Glucokinase gene islet promoter region variant (G-->A) at nucleotide -30 is not associated with reduced insulin secretion in Finns.

Rissanen J, Saarinen L, Heikkinen S, Kekäläinen P, Mykkänen L, Kuusisto J, Deeb SS, Laakso M.

Diabetes Care. 1998 Jul;21(7):1194-7.PMID: 9653619 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic glucokinase promoter polymorphism is associated with hepatic insulin resistance in Asian Indians.

Chiu KC, Chuang LM, Yoon C, Saad MF.

BMC Genet. 2000;1:2. Epub 2000 Nov 16.PMID: 11112984 [PubMed - indexed for MEDLINE]Related articlesFree article

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.

Sparsø T, Andersen G, Nielsen T, Burgdorf KS, Gjesing AP, Nielsen AL, Albrechtsen A, Rasmussen SS, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Madsbad S, Hansen T, Pedersen O.

Diabetologia. 2008 Jan;51(1):70-5. Epub 2007 Nov 16. Erratum in: Diabetologia. 2008 Feb;51(2):383. PMID: 18008060 [PubMed - indexed for MEDLINE]Related articles

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.

Lindner I, Rubin D, Helwig U, Nitz I, Hampe J, Schreiber S, Schrezenmeir J, Döring F.

Mol Nutr Food Res. 2006 Mar;50(3):270-4.PMID: 16521160 [PubMed - indexed for MEDLINE]Related articles

Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects.

Grarup N, Urhammer SA, Ek J, Albrechtsen A, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabetologia. 2006 Sep;49(9):2097-104. Epub 2006 Jul 25.PMID: 16865358 [PubMed - indexed for MEDLINE]Related articles

Studies of relationships between the GLUT10 Ala206Thr polymorphism and impaired insulin secretion.

Rose CS, Andersen G, Hamid YH, Glümer C, Drivsholm T, Borch-Johnsen K, Jørgensen T, Pedersen O, Hansen T.

Diabet Med. 2005 Jul;22(7):946-9.PMID: 15975113 [PubMed - indexed for MEDLINE]Related articles

Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study.

Vaxillaire M, Veslot J, Dina C, Proença C, Cauchi S, Charpentier G, Tichet J, Fumeron F, Marre M, Meyre D, Balkau B, Froguel P; DESIR Study Group.

Diabetes. 2008 Jan;57(1):244-54. Epub 2007 Oct 31.PMID: 17977958 [PubMed - indexed for MEDLINE]Related articlesFree article

The -30G>A polymorphism of the glucokinase gene promoter is associated with obesity in a population from southern Spain.

Gómez-Zumaquero JM, Rojo-Martínez G, García-Escobar E, Martín-Nuñez GM, Haro J, Esteva I, Ruiz de Adana M, Cuesta AL, Olveira G, Morcillo S, Soriguer F.

Obesity (Silver Spring). 2008 Aug;16(8):1973-5. Epub 2008 May 15.PMID: 18483479 [PubMed - indexed for MEDLINE]Related articles

The common T60N polymorphism of the lymphotoxin-alpha gene is associated with type 2 diabetes and other phenotypes of the metabolic syndrome.

Hamid YH, Urhammer SA, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabetologia. 2005 Mar;48(3):445-51. Epub 2005 Feb 24.PMID: 15729581 [PubMed - indexed for MEDLINE]Related articles

Glucokinase gene variations in Japanese-Americans with a family history of NIDDM.

Stone LM, Kahn SE, Deeb SS, Fujimoto WY, Porte D Jr.

Diabetes Care. 1994 Dec;17(12):1480-3.PMID: 7882822 [PubMed - indexed for MEDLINE]Related articles

Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes.

Andersen G, Overgaard J, Albrechtsen A, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabetologia. 2006 Jan;49(1):75-82. Epub 2005 Nov 12.PMID: 16284746 [PubMed - indexed for MEDLINE]Related articles

A common polymorphism in the promoter of the IGF-I gene associates with increased fasting serum triglyceride levels in glucose-tolerant subjects.

Nielsen EM, Hansen L, Lajer M, Andersen KL, Echwald SM, Urhammer SA, Hansen T, Pedersen O.

Clin Biochem. 2004 Aug;37(8):660-5.PMID: 15302607 [PubMed - indexed for MEDLINE]Related articles

A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses.

Weedon MN, Clark VJ, Qian Y, Ben-Shlomo Y, Timpson N, Ebrahim S, Lawlor DA, Pembrey ME, Ring S, Wilkin TJ, Voss LD, Jeffery AN, Metcalf B, Ferrucci L, Corsi AM, Murray A, Melzer D, Knight B, Shields B, Smith GD, Hattersley AT, Di Rienzo A, Frayling TM.

Am J Hum Genet. 2006 Dec;79(6):991-1001. Epub 2006 Oct 6.PMID: 17186458 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucokinase gene polymorphisms: a genetic marker for glucose intolerance in a cohort of elderly Finnish men.

McCarthy MI, Hitman GA, Hitchins M, Riikonen A, Stengård J, Nissinen A, Tuomilehto-Wolf E, Tuomilehto J.

Diabet Med. 1994 Mar;11(2):198-204.PMID: 8200207 [PubMed - indexed for MEDLINE]Related articles