PubMed

ATP-sensitive K+ channel signaling in glucokinase-deficient diabetes.

Remedi MS, Koster JC, Patton BL, Nichols CG.

Diabetes. 2005 Oct;54(10):2925-31.PMID: 16186394 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2.

Ravier MA, Nenquin M, Miki T, Seino S, Henquin JC.

Endocrinology. 2009 Jan;150(1):33-45. Epub 2008 Sep 11.PMID: 18787024 [PubMed - indexed for MEDLINE]Related articles

Diverse roles of K(ATP) channels learned from Kir6.2 genetically engineered mice.

Seino S, Iwanaga T, Nagashima K, Miki T.

Diabetes. 2000 Mar;49(3):311-8. Review.PMID: 10868950 [PubMed - indexed for MEDLINE]Related articlesFree article

Gastric inhibitory polypeptide is the major insulinotropic factor in K(ATP) null mice.

Tsukiyama K, Yamada Y, Miyawaki K, Hamasaki A, Nagashima K, Hosokawa M, Fujimoto S, Takahashi A, Toyoda K, Toyokuni S, Oiso Y, Seino Y.

Eur J Endocrinol. 2004 Sep;151(3):407-12.PMID: 15362972 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperinsulinism in mice with heterozygous loss of K(ATP) channels.

Remedi MS, Rocheleau JV, Tong A, Patton BL, McDaniel ML, Piston DW, Koster JC, Nichols CG.

Diabetologia. 2006 Oct;49(10):2368-78. Epub 2006 Aug 19.PMID: 16924481 [PubMed - indexed for MEDLINE]Related articles

K(ATP) channel knockout mice crossbred with transgenic mice expressing a dominant-negative form of human insulin receptor have glucose intolerance but not diabetes.

Kanezaki Y, Obata T, Matsushima R, Minami A, Yuasa T, Kishi K, Bando Y, Uehara H, Izumi K, Mitani T, Matsumoto M, Takeshita Y, Nakaya Y, Matsumoto T, Ebina Y.

Endocr J. 2004 Apr;51(2):133-44.PMID: 15118262 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes and hypoglycaemia in young children and mutations in the Kir6.2 subunit of the potassium channel: therapeutic consequences.

Flechtner I, de Lonlay P, Polak M.

Diabetes Metab. 2006 Dec;32(6):569-80. Review.PMID: 17296510 [PubMed - indexed for MEDLINE]Related articlesFree article

Diet-induced glucose intolerance in mice with decreased beta-cell ATP-sensitive K+ channels.

Remedi MS, Koster JC, Markova K, Seino S, Miki T, Patton BL, McDaniel ML, Nichols CG.

Diabetes. 2004 Dec;53(12):3159-67.PMID: 15561946 [PubMed - indexed for MEDLINE]Related articlesFree article

ATP-sensitive K+ channel-mediated glucose uptake is independent of IRS-1/phosphatidylinositol 3-kinase signaling.

Minami K, Morita M, Saraya A, Yano H, Terauchi Y, Miki T, Kuriyama T, Kadowaki T, Seino S.

Am J Physiol Endocrinol Metab. 2003 Dec;285(6):E1289-96. Epub 2003 Aug 21.PMID: 12933351 [PubMed - indexed for MEDLINE]Related articlesFree article

beta-cell hyperexcitability: from hyperinsulinism to diabetes.

Nichols CG, Koster JC, Remedi MS.

Diabetes Obes Metab. 2007 Nov;9 Suppl 2:81-8.PMID: 17919182 [PubMed - indexed for MEDLINE]Related articles

Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells.

Nenquin M, Szollosi A, Aguilar-Bryan L, Bryan J, Henquin JC.

J Biol Chem. 2004 Jul 30;279(31):32316-24. Epub 2004 Jun 1.PMID: 15175349 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels.

Szollosi A, Nenquin M, Aguilar-Bryan L, Bryan J, Henquin JC.

J Biol Chem. 2007 Jan 19;282(3):1747-56. Epub 2006 Nov 30.PMID: 17138557 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatocyte nuclear factor-4alpha is essential for glucose-stimulated insulin secretion by pancreatic beta-cells.

Miura A, Yamagata K, Kakei M, Hatakeyama H, Takahashi N, Fukui K, Nammo T, Yoneda K, Inoue Y, Sladek FM, Magnuson MA, Kasai H, Miyagawa J, Gonzalez FJ, Shimomura I.

J Biol Chem. 2006 Feb 24;281(8):5246-57. Epub 2005 Dec 23.PMID: 16377800 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility.

Miki T, Minami K, Shinozaki H, Matsumura K, Saraya A, Ikeda H, Yamada Y, Holst JJ, Seino S.

Diabetes. 2005 Apr;54(4):1056-63.PMID: 15793244 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of ATP-insensitive KATP channels in pancreatic beta-cells underlies a spectrum of diabetic phenotypes.

Koster JC, Remedi MS, Masia R, Patton B, Tong A, Nichols CG.

Diabetes. 2006 Nov;55(11):2957-64.PMID: 17065331 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic antidiabetic sulfonylureas in vivo: reversible effects on mouse pancreatic beta-cells.

Remedi MS, Nichols CG.

PLoS Med. 2008 Oct 28;5(10):e206.PMID: 18959471 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose modulation of ATP-sensitive K-currents in wild-type, homozygous and heterozygous glucokinase knock-out mice.

Sakura H, Ashcroft SJ, Terauchi Y, Kadowaki T, Ashcroft FM.

Diabetologia. 1998 Jun;41(6):654-9.PMID: 9662046 [PubMed - indexed for MEDLINE]Related articles

KATP channel-deficient pancreatic beta-cells are streptozotocin resistant because of lower GLUT2 activity.

Xu J, Zhang L, Chou A, Allaby T, Bélanger G, Radziuk J, Jasmin BJ, Miki T, Seino S, Renaud JM.

Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E326-35. Epub 2007 Nov 27.PMID: 18042662 [PubMed - indexed for MEDLINE]Related articlesFree article

Overnight culture unmasks glucose-induced insulin secretion in mouse islets lacking ATP-sensitive K+ channels by improving the triggering Ca2+ signal.

Szollosi A, Nenquin M, Henquin JC.

J Biol Chem. 2007 May 18;282(20):14768-76. Epub 2007 Mar 27.PMID: 17389589 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes and insulin secretion: the ATP-sensitive K+ channel (K ATP) connection.

Koster JC, Permutt MA, Nichols CG.

Diabetes. 2005 Nov;54(11):3065-72. Review.PMID: 16249427 [PubMed - indexed for MEDLINE]Related articlesFree article