PubMed

Attenuated Wnt signaling perturbs pancreatic growth but not pancreatic function.

Papadopoulou S, Edlund H.

Diabetes. 2005 Oct;54(10):2844-51.PMID: 16186384 [PubMed - indexed for MEDLINE]Related articlesFree article

Wnt5 signaling in vertebrate pancreas development.

Kim HJ, Schleiffarth JR, Jessurun J, Sumanas S, Petryk A, Lin S, Ekker SC.

BMC Biol. 2005 Oct 24;3:23.PMID: 16246260 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation.

Heller RS, Dichmann DS, Jensen J, Miller C, Wong G, Madsen OD, Serup P.

Dev Dyn. 2002 Nov;225(3):260-70.PMID: 12412008 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective expansion of the beta-cell compartment in the pancreas of keratinocyte growth factor transgenic mice.

Wagner M, Koschnick S, Beilke S, Frey M, Adler G, Schmid RM.

Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1139-47. Epub 2008 Mar 27.PMID: 18372394 [PubMed - indexed for MEDLINE]Related articlesFree article

Fgf10 maintains notch activation, stimulates proliferation, and blocks differentiation of pancreatic epithelial cells.

Hart A, Papadopoulou S, Edlund H.

Dev Dyn. 2003 Oct;228(2):185-93.PMID: 14517990 [PubMed - indexed for MEDLINE]Related articlesFree article

TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas.

Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK.

Dev Biol. 2007 May 15;305(2):508-21. Epub 2007 Mar 2.PMID: 17418116 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice.

Cantley J, Choudhury AI, Asare-Anane H, Selman C, Lingard S, Heffron H, Herrera P, Persaud SJ, Withers DJ.

Diabetologia. 2007 Jun;50(6):1248-56. Epub 2007 Mar 29.PMID: 17393136 [PubMed - indexed for MEDLINE]Related articles

Attenuation of FGF signalling in mouse beta-cells leads to diabetes.

Hart AW, Baeza N, Apelqvist A, Edlund H.

Nature. 2000 Dec 14;408(6814):864-8.PMID: 11130726 [PubMed - indexed for MEDLINE]Related articles

Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways.

Wente W, Efanov AM, Brenner M, Kharitonenkov A, Köster A, Sandusky GE, Sewing S, Treinies I, Zitzer H, Gromada J.

Diabetes. 2006 Sep;55(9):2470-8.PMID: 16936195 [PubMed - indexed for MEDLINE]Related articlesFree article

Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5.

Wang Z, Shu W, Lu MM, Morrisey EE.

Mol Cell Biol. 2005 Jun;25(12):5022-30.PMID: 15923619 [PubMed - indexed for MEDLINE]Related articlesFree article

The IIIb isoform of fibroblast growth factor receptor 2 is required for proper growth and branching of pancreatic ductal epithelium but not for differentiation of exocrine or endocrine cells.

Pulkkinen MA, Spencer-Dene B, Dickson C, Otonkoski T.

Mech Dev. 2003 Feb;120(2):167-75.PMID: 12559489 [PubMed - indexed for MEDLINE]Related articles

Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation.

Jonckheere N, Mayes E, Shih HP, Li B, Lioubinski O, Dai X, Sander M.

Dev Biol. 2008 Jun 15;318(2):224-35. Epub 2008 Mar 20.PMID: 18452912 [PubMed - indexed for MEDLINE]Related articlesFree article

FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development.

Norgaard GA, Jensen JN, Jensen J.

Dev Biol. 2003 Dec 15;264(2):323-38.PMID: 14651921 [PubMed - indexed for MEDLINE]Related articles

Islet hypertrophy following pancreatic disruption of Smad4 signaling.

Simeone DM, Zhang L, Treutelaar MK, Zhang L, Graziano K, Logsdon CD, Burant CF.

Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1305-16. Epub 2006 May 30.PMID: 16735447 [PubMed - indexed for MEDLINE]Related articlesFree article

FGFR3 is a negative regulator of the expansion of pancreatic epithelial cells.

Arnaud-Dabernat S, Kritzik M, Kayali AG, Zhang YQ, Liu G, Ungles C, Sarvetnick N.

Diabetes. 2007 Jan;56(1):96-106.PMID: 17192470 [PubMed - indexed for MEDLINE]Related articlesFree article

Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function.

Park S, Dong X, Fisher TL, Dunn S, Omer AK, Weir G, White MF.

J Biol Chem. 2006 Jan 13;281(2):1159-68. Epub 2005 Nov 4.PMID: 16272563 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia.

Means AL, Ray KC, Singh AB, Washington MK, Whitehead RH, Harris RC Jr, Wright CV, Coffey RJ Jr, Leach SD.

Gastroenterology. 2003 Apr;124(4):1020-36.PMID: 12671899 [PubMed - indexed for MEDLINE]Related articles

Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance.

Kido Y, Nakae J, Hribal ML, Xuan S, Efstratiadis A, Accili D.

J Biol Chem. 2002 Sep 27;277(39):36740-7. Epub 2002 Jul 5.PMID: 12101187 [PubMed - indexed for MEDLINE]Related articlesFree article

Fibroblast growth factors 7 and 10 are expressed in the human embryonic pancreatic mesenchyme and promote the proliferation of embryonic pancreatic epithelial cells.

Ye F, Duvillié B, Scharfmann R.

Diabetologia. 2005 Feb;48(2):277-81. Epub 2005 Feb 3.PMID: 15690149 [PubMed - indexed for MEDLINE]Related articles

Expression of Wnt, Frizzled, sFRP, and DKK genes in adult human pancreas.

Heller RS, Klein T, Ling Z, Heimberg H, Katoh M, Madsen OD, Serup P.

Gene Expr. 2003;11(3-4):141-7.PMID: 14686787 [PubMed - indexed for MEDLINE]Related articles