PubMed

Interaction of glucokinase with the liver regulatory protein is conferred by leucine-asparagine motifs of the enzyme.

Baltrusch S, Francini F, Lenzen S, Tiedge M.

Diabetes. 2005 Oct;54(10):2829-37.PMID: 16186382 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of glucokinase-binding protein epitopes by a phage-displayed peptide library. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel interaction partner.

Baltrusch S, Lenzen S, Okar DA, Lange AJ, Tiedge M.

J Biol Chem. 2001 Nov 23;276(47):43915-23. Epub 2001 Aug 24.PMID: 11522786 [PubMed - indexed for MEDLINE]Related articlesFree article

Amino acid conservation in animal glucokinases. Identification of residues implicated in the interaction with the regulatory protein.

Veiga-da-Cunha M, Courtois S, Michel A, Gosselain E, Van Schaftingen E.

J Biol Chem. 1996 Mar 15;271(11):6292-7.PMID: 8626423 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of mutations on the sensitivity of human beta-cell glucokinase to liver regulatory protein.

Veiga-da-Cunha M, Xu LZ, Lee YH, Marotta D, Pilkis SJ, Van Schaftingen E.

Diabetologia. 1996 Oct;39(10):1173-9.PMID: 8897004 [PubMed - indexed for MEDLINE]Related articles

Glucokinase regulatory protein is essential for the proper subcellular localisation of liver glucokinase.

de la Iglesia N, Veiga-da-Cunha M, Van Schaftingen E, Guinovart JJ, Ferrer JC.

FEBS Lett. 1999 Aug 6;456(2):332-8.PMID: 10456334 [PubMed - indexed for MEDLINE]Related articles

Importance of cysteine residues for the stability and catalytic activity of human pancreatic beta cell glucokinase.

Tiedge M, Richter T, Lenzen S.

Arch Biochem Biophys. 2000 Mar 15;375(2):251-60.PMID: 10700381 [PubMed - indexed for MEDLINE]Related articles

Catalytic activation of human glucokinase by substrate binding: residue contacts involved in the binding of D-glucose to the super-open form and conformational transitions.

Molnes J, Bjørkhaug L, Søvik O, Njølstad PR, Flatmark T.

FEBS J. 2008 May;275(10):2467-81. Epub 2008 Apr 7.PMID: 18397317 [PubMed - indexed for MEDLINE]Related articles

Study of the regulatory properties of glucokinase by site-directed mutagenesis: conversion of glucokinase to an enzyme with high affinity for glucose.

Moukil MA, Veiga-da-Cunha M, Van Schaftingen E.

Diabetes. 2000 Feb;49(2):195-201.PMID: 10868935 [PubMed - indexed for MEDLINE]Related articlesFree article

An allosteric activator of glucokinase impairs the interaction of glucokinase and glucokinase regulatory protein and regulates glucose metabolism.

Futamura M, Hosaka H, Kadotani A, Shimazaki H, Sasaki K, Ohyama S, Nishimura T, Eiki J, Nagata Y.

J Biol Chem. 2006 Dec 8;281(49):37668-74. Epub 2006 Oct 6.PMID: 17028192 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of human glucokinase intrinsic activity by SH reagents mirrors post-translational regulation of enzyme activity.

Tiedge M, Krug U, Lenzen S.

Biochim Biophys Acta. 1997 Feb 8;1337(2):175-90.PMID: 9048894 [PubMed - indexed for MEDLINE]Related articles

Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the young.

Gloyn AL, Odili S, Zelent D, Buettger C, Castleden HA, Steele AM, Stride A, Shiota C, Magnuson MA, Lorini R, d'Annunzio G, Stanley CA, Kwagh J, van Schaftingen E, Veiga-da-Cunha M, Barbetti F, Dunten P, Han Y, Grimsby J, Taub R, Ellard S, Hattersley AT, Matschinsky FM.

J Biol Chem. 2005 Apr 8;280(14):14105-13. Epub 2005 Jan 25.PMID: 15677479 [PubMed - indexed for MEDLINE]Related articlesFree article

Structure-function analysis of the alpha5 and the alpha13 helices of human glucokinase: description of two novel activating mutations.

Pedelini L, Garcia-Gimeno MA, Marina A, Gomez-Zumaquero JM, Rodriguez-Bada P, López-Enriquez S, Soriguer FC, Cuesta-Muñoz AL, Sanz P.

Protein Sci. 2005 Aug;14(8):2080-6. Epub 2005 Jun 29.PMID: 15987895 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of fructose 6-phosphate- and fructose 1-phosphate-binding residues in the regulatory protein of glucokinase.

Veiga-da-Cunha M, Van Schaftingen E.

J Biol Chem. 2002 Mar 8;277(10):8466-73. Epub 2001 Dec 27.PMID: 11756407 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of the regulatory protein of glucokinase in the glucose sensory mechanism of the hepatocyte.

de la Iglesia N, Mukhtar M, Seoane J, Guinovart JJ, Agius L.

J Biol Chem. 2000 Apr 7;275(14):10597-603.PMID: 10744755 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships.

Gidh-Jain M, Takeda J, Xu LZ, Lange AJ, Vionnet N, Stoffel M, Froguel P, Velho G, Sun F, Cohen D, et al.

Proc Natl Acad Sci U S A. 1993 Mar 1;90(5):1932-6.PMID: 8446612 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel cytosolic dual specificity phosphatase, interacting with glucokinase, increases glucose phosphorylation rate.

Muñoz-Alonso MJ, Guillemain G, Kassis N, Girard J, Burnol AF, Leturque A.

J Biol Chem. 2000 Oct 20;275(42):32406-12.PMID: 10913113 [PubMed - indexed for MEDLINE]Related articlesFree article

Definition of the consensus motif recognized by gamma-adaptin ear domains.

Mattera R, Ritter B, Sidhu SS, McPherson PS, Bonifacino JS.

J Biol Chem. 2004 Feb 27;279(9):8018-28. Epub 2003 Dec 9.PMID: 14665628 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucokinase thermolability and hepatic regulatory protein binding are essential factors for predicting the blood glucose phenotype of missense mutations.

Pino MF, Kim KA, Shelton KD, Lindner J, Odili S, Li C, Collins HW, Shiota M, Matschinsky FM, Magnuson MA.

J Biol Chem. 2007 May 4;282(18):13906-16. Epub 2007 Mar 12.PMID: 17353190 [PubMed - indexed for MEDLINE]Related articlesFree article

Biochemical basis of glucokinase activation and the regulation by glucokinase regulatory protein in naturally occurring mutations.

Heredia VV, Carlson TJ, Garcia E, Sun S.

J Biol Chem. 2006 Dec 29;281(52):40201-7. Epub 2006 Nov 2.PMID: 17082186 [PubMed - indexed for MEDLINE]Related articlesFree article

Alteration of enzyme function of the type II hexokinase C-terminal half on replacements of restricted regions by corresponding regions of glucokinase.

Kogure K, Yamamoto K, Majima E, Shinohara Y, Yamashita K, Terada H.

J Biol Chem. 1996 Jun 21;271(25):15230-6.PMID: 8662949 [PubMed - indexed for MEDLINE]Related articlesFree article