PubMed

Dose response of inhaled dry-powder insulin and dose equivalence to subcutaneous insulin lispro.

Rave KM, Nosek L, de la Peña A, Seger M, Ernest CS 2nd, Heinemann L, Batycky RP, Muchmore DB.

Diabetes Care. 2005 Oct;28(10):2400-5.PMID: 16186270 [PubMed - indexed for MEDLINE]Related articlesFree article

Smoking enhances absorption of insulin but reduces glucodynamic effects in individuals using the Lilly-Dura inhaled insulin system.

Wise S, Chien J, Yeo K, Richardson C.

Diabet Med. 2006 May;23(5):510-5.PMID: 16681559 [PubMed - indexed for MEDLINE]Related articles

AIR inhaled insulin in subjects with chronic obstructive pulmonary disease: pharmacokinetics, glucodynamics, safety, and tolerability.

Rave K, de la Peña A, Tibaldi FS, Zhang L, Silverman B, Hausmann M, Heinemann L, Muchmore DB.

Diabetes Care. 2007 Jul;30(7):1777-82. Epub 2007 Apr 24.PMID: 17456839 [PubMed - indexed for MEDLINE]Related articlesFree article

Dose-response relationships of inhaled insulin delivered via the Aerodose insulin inhaler and subcutaneously injected insulin in patients with type 2 diabetes.

Kim D, Mudaliar S, Chinnapongse S, Chu N, Boies SM, Davis T, Perera AD, Fishman RS, Shapiro DA, Henry R.

Diabetes Care. 2003 Oct;26(10):2842-7.PMID: 14514589 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy and safety of preprandial human insulin inhalation powder versus injectable insulin in patients with type 1 diabetes.

Garg S, Rosenstock J, Silverman BL, Sun B, Konkoy CS, de la Peña A, Muchmore DB.

Diabetologia. 2006 May;49(5):891-9. Epub 2006 Feb 28.PMID: 16506054 [PubMed - indexed for MEDLINE]Related articles

Effect of inhaled insulin on patient-reported outcomes and treatment preference in patients with type 1 diabetes.

Hayes RP, Muchmore D, Schmitke J.

Curr Med Res Opin. 2007 Feb;23(2):435-42.PMID: 17288697 [PubMed - indexed for MEDLINE]Related articles

AIR inhaled insulin versus subcutaneous insulin: pharmacokinetics, glucodynamics, and pulmonary function in asthma.

Wolzt M, de la Peña A, Berclaz PY, Tibaldi FS, Gates JR, Muchmore DB.

Diabetes Care. 2008 Apr;31(4):735-40. Epub 2008 Jan 11.PMID: 18192544 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhaled micronized crystalline human insulin using a dry powder inhaler: dose-response and time-action profiles.

Rave K, Nosek L, Heinemann L, Gonzales C, Ernest CS, Chien J, Muchmore D.

Diabet Med. 2004 Jul;21(7):763-8.PMID: 15209771 [PubMed - indexed for MEDLINE]Related articles

Comparison of pharmacokinetic and pharmacodynamic properties of single-dose oral insulin spray and subcutaneous insulin injection in healthy subjects using the euglycemic clamp technique.

Cernea S, Kidron M, Wohlgelernter J, Modi P, Raz I.

Clin Ther. 2004 Dec;26(12):2084-91.PMID: 15823772 [PubMed - indexed for MEDLINE]Related articles

Time-action profile of inhaled insulin in comparison with subcutaneously injected insulin lispro and regular human insulin.

Rave K, Bott S, Heinemann L, Sha S, Becker RH, Willavize SA, Heise T.

Diabetes Care. 2005 May;28(5):1077-82.PMID: 15855570 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of upper respiratory tract infection on AIR inhaled insulin pharmacokinetics and glucodynamics in healthy subjects.

Gern JE, Stone CK, Nakano M, Muchmore DB, de la Peña A, Park S, Suri A, Tibaldi F, Soon D, Busse WW.

Clin Pharmacol Ther. 2008 Feb;83(2):307-11. Epub 2007 Jul 11.PMID: 17625517 [PubMed - indexed for MEDLINE]Related articles

Pramlintide reduces postprandial glucose excursions when added to regular insulin or insulin lispro in subjects with type 1 diabetes: a dose-timing study.

Weyer C, Gottlieb A, Kim DD, Lutz K, Schwartz S, Gutierrez M, Wang Y, Ruggles JA, Kolterman OG, Maggs DG.

Diabetes Care. 2003 Nov;26(11):3074-9.PMID: 14578242 [PubMed - indexed for MEDLINE]Related articlesFree article

Intramuscular versus subcutaneous injection of soluble and lispro insulin: comparison of metabolic effects in healthy subjects.

Rave K, Heise T, Weyer C, Herrnberger J, Bender R, Hirschberger S, Heinemann L.

Diabet Med. 1998 Sep;15(9):747-51.PMID: 9737803 [PubMed - indexed for MEDLINE]Related articles

Dose-response relationship of an oral insulin spray in six patients with type 1 diabetes: a single-center, randomized, single-blind, 5-way crossover study.

Cernea S, Kidron M, Wohlgelernter J, Raz I.

Clin Ther. 2005 Oct;27(10):1562-70.PMID: 16330292 [PubMed - indexed for MEDLINE]Related articles

Time-action profiles of novel premixed preparations of insulin lispro and NPL insulin.

Heise T, Weyer C, Serwas A, Heinrichs S, Osinga J, Roach P, Woodworth J, Gudat U, Heinemann L.

Diabetes Care. 1998 May;21(5):800-3.PMID: 9589244 [PubMed - indexed for MEDLINE]Related articlesFree article

Review of phase 2 studies utilizing the AIR particle technology in the delivery of human insulin inhalation powder versus subcutaneous regular or lispro insulin in subjects with type 1 or type 2 diabetes.

Ellis SL, Gemperline KA, Garg SK.

Diabetes Technol Ther. 2007 Jun;9 Suppl 1:S48-56.PMID: 17563304 [PubMed - indexed for MEDLINE]Related articles

A double-blind, randomized, dose-response study investigating the pharmacodynamic and pharmacokinetic properties of the long-acting insulin analog detemir.

Plank J, Bodenlenz M, Sinner F, Magnes C, Görzer E, Regittnig W, Endahl LA, Draeger E, Zdravkovic M, Pieber TR.

Diabetes Care. 2005 May;28(5):1107-12.PMID: 15855574 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of smoking cessation, acute re-exposure and nicotine replacement in smokers on AIR inhaled insulin pharmacokinetics and glucodynamics.

Pan AX, de la Peña A, Yeo KP, Chan C, Loh MT, Wise SD, Silverman BL, Muchmore DB.

Br J Clin Pharmacol. 2008 Apr;65(4):480-7. Epub 2007 Oct 8.PMID: 17922880 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin glulisine, a new rapid-acting insulin analogue, displays a rapid time-action profile in obese non-diabetic subjects.

Becker RH, Frick AD, Burger F, Potgieter JH, Scholtz H.

Exp Clin Endocrinol Diabetes. 2005 Sep;113(8):435-43.PMID: 16151977 [PubMed - indexed for MEDLINE]Related articles

The effect of insulin antibodies on the metabolic action of inhaled and subcutaneous insulin: a prospective randomized pharmacodynamic study.

Heise T, Bott S, Tusek C, Stephan JA, Kawabata T, Finco-Kent D, Liu C, Krasner A.

Diabetes Care. 2005 Sep;28(9):2161-9.PMID: 16123484 [PubMed - indexed for MEDLINE]Related articlesFree article