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    Results: 1 to 20 of 567

    1.

    Overexpression of platelet-derived growth factor receptor alpha in breast cancer is associated with tumour progression.

    Carvalho I, Milanezi F, Martins A, Reis RM, Schmitt F.

    Breast Cancer Res. 2005;7(5):R788-95. Epub 2005 Aug 1.

    PMID:
    16168125
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Molecular characterization of PDGFR-alpha/PDGF-A and c-KIT/SCF in gliosarcomas.

    Reis RM, Martins A, Ribeiro SA, Basto D, Longatto-Filho A, Schmitt FC, Lopes JM.

    Cell Oncol. 2005;27(5-6):319-26.

    PMID:
    16373964
    [PubMed - indexed for MEDLINE]
    3.

    Analysis of mutation and expression of c-kit and PDGFR-alpha gene in gastrointestinal stromal tumor.

    Zheng S, Chen LR, Wang HJ, Chen SZ.

    Hepatogastroenterology. 2007 Dec;54(80):2285-90.

    PMID:
    18265649
    [PubMed - indexed for MEDLINE]
    4.

    Protein expression of KIT and gene mutation of c-kit and PDGFRs in Ewing sarcomas.

    Do I, Araujo ES, Kalil RK, Bacchini P, Bertoni F, Unni KK, Park YK.

    Pathol Res Pract. 2007;203(3):127-34. Epub 2007 Feb 12.

    PMID:
    17298867
    [PubMed - indexed for MEDLINE]
    5.

    Expression and mutational analysis of tyrosine kinase receptors c-kit, PDGFRalpha, and PDGFRbeta in ovarian cancers.

    Wilczynski SP, Chen YY, Chen W, Howell SB, Shively JE, Alberts DS.

    Hum Pathol. 2005 Mar;36(3):242-9.

    PMID:
    15791568
    [PubMed - indexed for MEDLINE]
    6.

    KIT and platelet-derived growth factor receptor alpha tyrosine kinase gene mutations and KIT amplifications in human solid tumors.

    Sihto H, Sarlomo-Rikala M, Tynninen O, Tanner M, Andersson LC, Franssila K, Nupponen NN, Joensuu H.

    J Clin Oncol. 2005 Jan 1;23(1):49-57. Epub 2004 Nov 15.

    PMID:
    15545668
    [PubMed - indexed for MEDLINE]
    7.

    Imatinib mesylate inhibits platelet-derived growth factor receptor phosphorylation of melanoma cells but does not affect tumorigenicity in vivo.

    McGary EC, Onn A, Mills L, Heimberger A, Eton O, Thomas GW, Shtivelband M, Bar-Eli M.

    J Invest Dermatol. 2004 Feb;122(2):400-5.

    PMID:
    15009722
    [PubMed - indexed for MEDLINE]
    Free Article
    8.

    Imatinib mesylate inhibits cell invasion of malignant peripheral nerve sheath tumor induced by platelet-derived growth factor-BB.

    Aoki M, Nabeshima K, Koga K, Hamasaki M, Suzumiya J, Tamura K, Iwasaki H.

    Lab Invest. 2007 Aug;87(8):767-79. Epub 2007 Jun 11.

    PMID:
    17558420
    [PubMed - indexed for MEDLINE]
    Free Article
    9.
    10.

    Imatinib mesylate inhibits Leydig cell tumor growth: evidence for in vitro and in vivo activity.

    Basciani S, Brama M, Mariani S, De Luca G, Arizzi M, Vesci L, Pisano C, Dolci S, Spera G, Gnessi L.

    Cancer Res. 2005 Mar 1;65(5):1897-903.

    PMID:
    15753388
    [PubMed - indexed for MEDLINE]
    Free Article
    11.

    Activating mutations in c-KIT and PDGFRalpha are exclusively found in gastrointestinal stromal tumors and not in other tumors overexpressing these imatinib mesylate target genes.

    Burger H, den Bakker MA, Kros JM, van Tol H, de Bruin AM, Oosterhuis W, van den Ingh HF, van der Harst E, de Schipper HP, Wiemer EA, Nooter K.

    Cancer Biol Ther. 2005 Nov;4(11):1270-4. Epub 2005 Nov 18.

    PMID:
    16294026
    [PubMed - indexed for MEDLINE]
    Free Article
    12.

    Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors.

    Hirota S, Ohashi A, Nishida T, Isozaki K, Kinoshita K, Shinomura Y, Kitamura Y.

    Gastroenterology. 2003 Sep;125(3):660-7.

    PMID:
    12949711
    [PubMed - indexed for MEDLINE]
    13.

    Expression of the platelet-derived growth factor receptor in prostate cancer and treatment implications with tyrosine kinase inhibitors.

    Hofer MD, Fecko A, Shen R, Setlur SR, Pienta KG, Tomlins SA, Chinnaiyan AM, Rubin MA.

    Neoplasia. 2004 Sep-Oct;6(5):503-12.

    PMID:
    15548358
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors.

    McDermott U, Ames RY, Iafrate AJ, Maheswaran S, Stubbs H, Greninger P, McCutcheon K, Milano R, Tam A, Lee DY, Lucien L, Brannigan BW, Ulkus LE, Ma XJ, Erlander MG, Haber DA, Sharma SV, Settleman J.

    Cancer Res. 2009 May 1;69(9):3937-46. Epub 2009 Apr 14.

    PMID:
    19366796
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    15.

    Imatinib mesylate (Gleevec) in advanced breast cancer-expressing C-Kit or PDGFR-beta: clinical activity and biological correlations.

    Cristofanilli M, Morandi P, Krishnamurthy S, Reuben JM, Lee BN, Francis D, Booser DJ, Green MC, Arun BK, Pusztai L, Lopez A, Islam R, Valero V, Hortobagyi GN.

    Ann Oncol. 2008 Oct;19(10):1713-9. Epub 2008 May 29.

    PMID:
    18515258
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    16.

    Expression, mutational analysis and in vitro response of imatinib mesylate and nilotinib target genes in ovarian granulosa cell tumors.

    Chu S, Alexiadis M, Fuller PJ.

    Gynecol Oncol. 2008 Jan;108(1):182-90. Epub 2007 Oct 29.

    PMID:
    18028988
    [PubMed - indexed for MEDLINE]
    17.

    Osteoblast-conditioned medium promotes proliferation and sensitizes breast cancer cells to imatinib treatment.

    Brama M, Basciani S, Cherubini S, Mariani S, Migliaccio S, Arizzi M, Rosano G, Spera G, Gnessi L.

    Endocr Relat Cancer. 2007 Mar;14(1):61-72.

    PMID:
    17395975
    [PubMed - indexed for MEDLINE]
    Free Article
    18.

    Inhibition of platelet-derived growth factor receptor signaling restricts the growth of human breast cancer in the bone of nude mice.

    Lev DC, Kim SJ, Onn A, Stone V, Nam DH, Yazici S, Fidler IJ, Price JE.

    Clin Cancer Res. 2005 Jan 1;11(1):306-14.

    PMID:
    15671560
    [PubMed - indexed for MEDLINE]
    Free Article
    20.

    Immunohistochemical analysis of platelet-derived growth factor receptor-alpha, -beta, c-kit, c-abl, and arg proteins in glioblastoma: possible implications for patient selection for imatinib mesylate therapy.

    Haberler C, Gelpi E, Marosi C, Rössler K, Birner P, Budka H, Hainfellner JA.

    J Neurooncol. 2006 Jan;76(2):105-9.

    PMID:
    16205964
    [PubMed - indexed for MEDLINE]

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