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    Results: 1 to 20 of 157

    1.

    Differential responses to doxorubicin-induced phosphorylation and activation of Akt in human breast cancer cells.

    Li X, Lu Y, Liang K, Liu B, Fan Z.

    Breast Cancer Res. 2005;7(5):R589-97. Epub 2005 May 24.

    PMID:
    16168102
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Targeting the phosphatidylinositol 3-kinase/Akt pathway for enhancing breast cancer cells to radiotherapy.

    Liang K, Jin W, Knuefermann C, Schmidt M, Mills GB, Ang KK, Milas L, Fan Z.

    Mol Cancer Ther. 2003 Apr;2(4):353-60.

    PMID:
    12700279
    [PubMed - indexed for MEDLINE]
    Free Article
    3.

    Sensitization of breast cancer cells to radiation by trastuzumab.

    Liang K, Lu Y, Jin W, Ang KK, Milas L, Fan Z.

    Mol Cancer Ther. 2003 Nov;2(11):1113-20.

    PMID:
    14617784
    [PubMed - indexed for MEDLINE]
    Free Article
    4.

    HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells.

    Knuefermann C, Lu Y, Liu B, Jin W, Liang K, Wu L, Schmidt M, Mills GB, Mendelsohn J, Fan Z.

    Oncogene. 2003 May 22;22(21):3205-12.

    PMID:
    12761490
    [PubMed - indexed for MEDLINE]
    6.

    Activation of the phosphatidylinositol 3-kinase/Akt pathway prevents radiation-induced apoptosis in breast cancer cells.

    Söderlund K, Pérez-Tenorio G, Stål O.

    Int J Oncol. 2005 Jan;26(1):25-32.

    PMID:
    15586221
    [PubMed - indexed for MEDLINE]
    7.

    Autocrine signalling through erbB receptors promotes constitutive activation of protein kinase B/Akt in breast cancer cell lines.

    Nicholson KM, Streuli CH, Anderson NG.

    Breast Cancer Res Treat. 2003 Sep;81(2):117-28.

    PMID:
    14572154
    [PubMed - indexed for MEDLINE]
    8.

    The heat shock protein 90 inhibitor geldanamycin and the ErbB inhibitor ZD1839 promote rapid PP1 phosphatase-dependent inactivation of AKT in ErbB2 overexpressing breast cancer cells.

    Xu W, Yuan X, Jung YJ, Yang Y, Basso A, Rosen N, Chung EJ, Trepel J, Neckers L.

    Cancer Res. 2003 Nov 15;63(22):7777-84.

    PMID:
    14633703
    [PubMed - indexed for MEDLINE]
    Free Article
    10.

    Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells.

    Clark AS, West K, Streicher S, Dennis PA.

    Mol Cancer Ther. 2002 Jul;1(9):707-17.

    PMID:
    12479367
    [PubMed - indexed for MEDLINE]
    Free Article
    11.

    Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates.

    Li S, Zhou Y, Wang R, Zhang H, Dong Y, Ip C.

    Mol Cancer Ther. 2007 Mar;6(3):1031-8. Epub 2007 Mar 5.

    PMID:
    17339365
    [PubMed - indexed for MEDLINE]
    Free Article
    12.

    Overcoming trastuzumab resistance in HER2-overexpressing breast cancer cells by using a novel celecoxib-derived phosphoinositide-dependent kinase-1 inhibitor.

    Tseng PH, Wang YC, Weng SC, Weng JR, Chen CS, Brueggemeier RW, Shapiro CL, Chen CY, Dunn SE, Pollak M, Chen CS.

    Mol Pharmacol. 2006 Nov;70(5):1534-41. Epub 2006 Aug 3.

    PMID:
    16887935
    [PubMed - indexed for MEDLINE]
    Free Article
    13.

    Differential roles of phosphoinositide-dependent protein kinase-1 and akt1 expression and phosphorylation in breast cancer cell resistance to Paclitaxel, Doxorubicin, and gemcitabine.

    Liang K, Lu Y, Li X, Zeng X, Glazer RI, Mills GB, Fan Z.

    Mol Pharmacol. 2006 Sep;70(3):1045-52. Epub 2006 Jun 16.

    PMID:
    16782806
    [PubMed - indexed for MEDLINE]
    Free Article
    14.

    QLT0267, a small molecule inhibitor targeting integrin-linked kinase (ILK), and docetaxel can combine to produce synergistic interactions linked to enhanced cytotoxicity, reductions in P-AKT levels, altered F-actin architecture and improved treatment outcomes in an orthotopic breast cancer model.

    Kalra J, Warburton C, Fang K, Edwards L, Daynard T, Waterhouse D, Dragowska W, Sutherland BW, Dedhar S, Gelmon K, Bally M.

    Breast Cancer Res. 2009;11(3):R25. Epub 2009 May 1.

    PMID:
    19409087
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    16.

    Phosphoinositide 3-kinase/Akt pathway plays an important role in chemoresistance of gastric cancer cells against etoposide and doxorubicin induced cell death.

    Yu HG, Ai YW, Yu LL, Zhou XD, Liu J, Li JH, Xu XM, Liu S, Chen J, Liu F, Qi YL, Deng Q, Cao J, Liu SQ, Luo HS, Yu JP.

    Int J Cancer. 2008 Jan 15;122(2):433-43.

    PMID:
    17935137
    [PubMed - indexed for MEDLINE]
    17.

    Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells.

    Asanuma H, Torigoe T, Kamiguchi K, Hirohashi Y, Ohmura T, Hirata K, Sato M, Sato N.

    Cancer Res. 2005 Dec 1;65(23):11018-25.

    PMID:
    16322251
    [PubMed - indexed for MEDLINE]
    Free Article
    18.

    Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells is mediated by c-Jun NH2-terminal kinase and Akt.

    Sunters A, Madureira PA, Pomeranz KM, Aubert M, Brosens JJ, Cook SJ, Burgering BM, Coombes RC, Lam EW.

    Cancer Res. 2006 Jan 1;66(1):212-20.

    PMID:
    16397234
    [PubMed - indexed for MEDLINE]
    Free Article
    19.

    Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells.

    Taylor JR, Lehmann BD, Chappell WH, Abrams SL, Steelman LS, McCubrey JA.

    Oncotarget. 2011 Aug;2(8):610-26.

    PMID:
    21881167
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    [Impact of PI3K /Akt /mdm2 signaling pathway on the sensitivity of gastric cancer cell line SGC7901 to doxorubicin].

    Ai YW, Yu HG, Yu JP, Yang Y, Li H, Hu XW, Luo HS.

    Zhonghua Zhong Liu Za Zhi. 2008 Jul;30(7):494-7. Chinese.

    PMID:
    19062713
    [PubMed - indexed for MEDLINE]

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