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    Results: 1 to 20 of 116

    1.

    Possibility of selection against mtDNA mutations in tumors.

    Khaidakov M, Shmookler Reis RJ.

    Mol Cancer. 2005 Sep 13;4:36. Review.PMID: 16159390 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues.

    Nekhaeva E, Bodyak ND, Kraytsberg Y, McGrath SB, Van Orsouw NJ, Pluzhnikov A, Wei JY, Vijg J, Khrapko K.

    Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5521-6. Epub 2002 Apr 9.PMID: 11943860 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Somatic mitochondrial DNA mutations in neurofibromatosis type 1-associated tumors.

    Kurtz A, Lueth M, Kluwe L, Zhang T, Foster R, Mautner VF, Hartmann M, Tan DJ, Martuza RL, Friedrich RE, Driever PH, Wong LJ.

    Mol Cancer Res. 2004 Aug;2(8):433-41.PMID: 15328370 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection.

    Coller HA, Khrapko K, Bodyak ND, Nekhaeva E, Herrero-Jimenez P, Thilly WG.

    Nat Genet. 2001 Jun;28(2):147-50.PMID: 11381261 [PubMed - indexed for MEDLINE]Related articles

    5.

    Significance of somatic mutations and content alteration of mitochondrial DNA in esophageal cancer.

    Tan DJ, Chang J, Liu LL, Bai RK, Wang YF, Yeh KT, Wong LJ.

    BMC Cancer. 2006 Apr 18;6:93.PMID: 16620376 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    MtDNA mutation pattern in tumors and human evolution are shaped by similar selective constraints.

    Zhidkov I, Livneh EA, Rubin E, Mishmar D.

    Genome Res. 2009 Apr;19(4):576-80. Epub 2009 Feb 10.PMID: 19211544 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Contribution of somatic mutations in the mitochondrial genome to the development of cancer and tolerance against anticancer drugs.

    Ohta S.

    Oncogene. 2006 Aug 7;25(34):4768-76. Review.PMID: 16892089 [PubMed - indexed for MEDLINE]Related articles

    8.

    Selection against pathogenic mtDNA mutations in a stem cell population leads to the loss of the 3243A-->G mutation in blood.

    Rajasimha HK, Chinnery PF, Samuels DC.

    Am J Hum Genet. 2008 Feb;82(2):333-43.PMID: 18252214 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Role of mitochondrial mutations in cancer.

    Baysal BE.

    Endocr Pathol. 2006 Fall;17(3):203-12. Review.PMID: 17308357 [PubMed - indexed for MEDLINE]Related articles

    10.

    Strong purifying selection in transmission of mammalian mitochondrial DNA.

    Stewart JB, Freyer C, Elson JL, Wredenberg A, Cansu Z, Trifunovic A, Larsson NG.

    PLoS Biol. 2008 Jan;6(1):e10.PMID: 18232733 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Mitochondrial DNA mutations in cancer: a review.

    Santos C, Martínez M, Lima M, Hao YJ, Simões N, Montiel R.

    Curr Top Med Chem. 2008;8(15):1351-66. Review.PMID: 18991723 [PubMed - indexed for MEDLINE]Related articles

    12.

    Frequent intracellular clonal expansions of somatic mtDNA mutations: significance and mechanisms.

    Coller HA, Bodyak ND, Khrapko K.

    Ann N Y Acad Sci. 2002 Apr;959:434-47.PMID: 11976216 [PubMed - indexed for MEDLINE]Related articles

    13.

    Mitochondrial DNA mutations in human cancer.

    Chatterjee A, Mambo E, Sidransky D.

    Oncogene. 2006 Aug 7;25(34):4663-74. Review.PMID: 16892080 [PubMed - indexed for MEDLINE]Related articles

    14.

    Mitochondrial DNA mutations in differentiated thyroid cancer with respect to the age factor.

    Witte J, Lehmann S, Wulfert M, Yang Q, Röher HD.

    World J Surg. 2007 Jan;31(1):51-9.PMID: 17171498 [PubMed - indexed for MEDLINE]Related articles

    15.

    Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma.

    Mayr JA, Meierhofer D, Zimmermann F, Feichtinger R, Kögler C, Ratschek M, Schmeller N, Sperl W, Kofler B.

    Clin Cancer Res. 2008 Apr 15;14(8):2270-5.PMID: 18413815 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Mutations in mitochondrial DNA polymerase-gamma promote breast tumorigenesis.

    Singh KK, Ayyasamy V, Owens KM, Koul MS, Vujcic M.

    J Hum Genet. 2009 Sep;54(9):516-24. Epub 2009 Jul 24.PMID: 19629138 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Performance of mitochondrial DNA mutations detecting early stage cancer.

    Jakupciak JP, Maragh S, Markowitz ME, Greenberg AK, Hoque MO, Maitra A, Barker PE, Wagner PD, Rom WN, Srivastava S, Sidransky D, O'Connell CD.

    BMC Cancer. 2008 Oct 3;8:285.PMID: 18834532 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Is selection required for the accumulation of somatic mitochondrial DNA mutations in post-mitotic cells?

    Durham SE, Samuels DC, Chinnery PF.

    Neuromuscul Disord. 2006 Jun;16(6):381-6. Epub 2006 May 8.PMID: 16684599 [PubMed - indexed for MEDLINE]Related articles

    19.

    The low abundance of clonally expanded mitochondrial DNA point mutations in aged substantia nigra neurons.

    Reeve AK, Krishnan KJ, Taylor G, Elson JL, Bender A, Taylor RW, Morris CM, Turnbull DM.

    Aging Cell. 2009 Aug;8(4):496-8. Epub 2009 May 31.PMID: 19489744 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Hypervariable sites in the mtDNA control region are mutational hotspots.

    Stoneking M.

    Am J Hum Genet. 2000 Oct;67(4):1029-32. Epub 2000 Aug 30.PMID: 10968778 [PubMed - indexed for MEDLINE]Related articlesFree article

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