PubMed

Melatonin, a potent agent in antioxidative defense: actions as a natural food constituent, gastrointestinal factor, drug and prodrug.

Hardeland R, Pandi-Perumal SR.

Nutr Metab (Lond). 2005 Sep 10;2:22.PMID: 16153306 [PubMed]Related articlesFree article

Antioxidative protection by melatonin: multiplicity of mechanisms from radical detoxification to radical avoidance.

Hardeland R.

Endocrine. 2005 Jul;27(2):119-30. Review.PMID: 16217125 [PubMed - indexed for MEDLINE]Related articles

Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages.

Mayo JC, Sainz RM, Tan DX, Hardeland R, Leon J, Rodriguez C, Reiter RJ.

J Neuroimmunol. 2005 Aug;165(1-2):139-49.PMID: 15975667 [PubMed - indexed for MEDLINE]Related articles

Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction.

Ressmeyer AR, Mayo JC, Zelosko V, Sáinz RM, Tan DX, Poeggeler B, Antolín I, Zsizsik BK, Reiter RJ, Hardeland R.

Redox Rep. 2003;8(4):205-13.PMID: 14599344 [PubMed - indexed for MEDLINE]Related articles

Significance of melatonin in antioxidative defense system: reactions and products.

Tan DX, Manchester LC, Reiter RJ, Qi WB, Karbownik M, Calvo JR.

Biol Signals Recept. 2000 May-Aug;9(3-4):137-59. Review.PMID: 10899700 [PubMed - indexed for MEDLINE]Related articles

One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species?

Tan DX, Manchester LC, Terron MP, Flores LJ, Reiter RJ.

J Pineal Res. 2007 Jan;42(1):28-42. Review.PMID: 17198536 [PubMed - indexed for MEDLINE]Related articles

Biogenic amines in the reduction of oxidative stress: melatonin and its metabolites.

Reiter RJ, Tan DX, Jou MJ, Korkmaz A, Manchester LC, Paredes SD.

Neuro Endocrinol Lett. 2008 Aug;29(4):391-8. Review.PMID: 18766165 [PubMed - indexed for MEDLINE]Related articles

Melatonin reduces oxidant damage and promotes mitochondrial respiration: implications for aging.

Reiter RJ, Tan DX, Manchester LC, El-Sawi MR.

Ann N Y Acad Sci. 2002 Apr;959:238-50. Review.PMID: 11976199 [PubMed - indexed for MEDLINE]Related articles

Localization and biological activities of melatonin in intact and diseased gastrointestinal tract (GIT).

Konturek SJ, Konturek PC, Brzozowska I, Pawlik M, Sliwowski Z, Cześnikiewicz-Guzik M, Kwiecień S, Brzozowski T, Bubenik GA, Pawlik WW.

J Physiol Pharmacol. 2007 Sep;58(3):381-405. Review.PMID: 17928638 [PubMed - indexed for MEDLINE]Related articlesFree article

N1-acetyl-N2-formyl-5-methoxykynuramine, a biogenic amine and melatonin metabolite, functions as a potent antioxidant.

Tan DX, Manchester LC, Burkhardt S, Sainz RM, Mayo JC, Kohen R, Shohami E, Huo YS, Hardeland R, Reiter RJ.

FASEB J. 2001 Oct;15(12):2294-6. Epub 2001 Aug 17.PMID: 11511530 [PubMed - indexed for MEDLINE]Related articlesFree article

Melatonin.

Hardeland R, Pandi-Perumal SR, Cardinali DP.

Int J Biochem Cell Biol. 2006 Mar;38(3):313-6. Epub 2005 Sep 27. Review.PMID: 16219483 [PubMed - indexed for MEDLINE]Related articles

Oxidation of melatonin and its catabolites, N1-acetyl-N2 -formyl-5-methoxykynuramine and N1-acetyl-5-methoxykynuramine, by activated leukocytes.

Silva SO, Rodrigues MR, Carvalho SR, Catalani LH, Campa A, Ximenes VF.

J Pineal Res. 2004 Oct;37(3):171-5.PMID: 15357661 [PubMed - indexed for MEDLINE]Related articles

Photocatalytic actions of the pesticide metabolite 2-hydroxyquinoxaline: destruction of antioxidant vitamins and biogenic amines - implications of organic redox cycling.

Behrends A, Hardeland R, Ness H, Grube S, Poeggeler B, Haldar C.

Redox Rep. 2004;9(5):279-88.PMID: 15606981 [PubMed - indexed for MEDLINE]Related articles

Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in humans.

Reiter RJ, Tan DX, Mayo JC, Sainz RM, Leon J, Czarnocki Z.

Acta Biochim Pol. 2003;50(4):1129-46. Review.PMID: 14740000 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxygen radical detoxification processes during aging: the functional importance of melatonin.

Reiter RJ.

Aging (Milano). 1995 Oct;7(5):340-51. Review.PMID: 8719600 [PubMed - indexed for MEDLINE]Related articles

Melatonin: new places in therapy.

Maharaj DS, Glass BD, Daya S.

Biosci Rep. 2007 Dec;27(6):299-320. Review.PMID: 17828452 [PubMed - indexed for MEDLINE]Related articles

Reactive oxygen and nitrogen species and cellular and organismal decline: amelioration with melatonin.

Reiter RJ, Tan DX, Burkhardt S.

Mech Ageing Dev. 2002 Apr 30;123(8):1007-19. Review.PMID: 12044950 [PubMed - indexed for MEDLINE]Related articles

Melatonin: reducing molecular pathology and dysfunction due to free radicals and associated reactants.

Reiter RJ, Tan DX, Allegra M.

Neuro Endocrinol Lett. 2002 Apr;23 Suppl 1:3-8. Review.PMID: 12019343 [PubMed - indexed for MEDLINE]Related articles

Optimized synthesis of the melatonin metabolite N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK).

Ximenes VF.

J Pineal Res. 2008 Oct;45(3):297-301. Epub 2008 Mar 26.PMID: 18373552 [PubMed - indexed for MEDLINE]Related articles

Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical.

Tan DX, Hardeland R, Manchester LC, Poeggeler B, Lopez-Burillo S, Mayo JC, Sainz RM, Reiter RJ.

J Pineal Res. 2003 May;34(4):249-59.PMID: 12662346 [PubMed - indexed for MEDLINE]Related articles