PubMed

Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6.

Bach D, Naon D, Pich S, Soriano FX, Vega N, Rieusset J, Laville M, Guillet C, Boirie Y, Wallberg-Henriksson H, Manco M, Calvani M, Castagneto M, Palacín M, Mingrone G, Zierath JR, Vidal H, Zorzano A.

Diabetes. 2005 Sep;54(9):2685-93.PMID: 16123358 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids.

Vidal-Puig AJ, Considine RV, Jimenez-Liñan M, Werman A, Pories WJ, Caro JF, Flier JS.

J Clin Invest. 1997 May 15;99(10):2416-22.PMID: 9153284 [PubMed - indexed for MEDLINE]Related articlesFree article

Subcutaneous adipose tissue expression of tumour necrosis factor-alpha is not associated with whole body insulin resistance in obese nondiabetic or in type-2 diabetic subjects.

Koistinen HA, Bastard JP, Dusserre E, Ebeling P, Zegari N, Andreelli F, Jardel C, Donner M, Meyer L, Moulin P, Hainque B, Riou JP, Laville M, Koivisto VA, Vidal H.

Eur J Clin Invest. 2000 Apr;30(4):302-10.PMID: 10759878 [PubMed - indexed for MEDLINE]Related articles

Could the low level of expression of the gene encoding skeletal muscle mitofusin-2 account for the metabolic inflexibility of obesity?

Mingrone G, Manco M, Calvani M, Castagneto M, Naon D, Zorzano A.

Diabetologia. 2005 Oct;48(10):2108-14. Epub 2005 Sep 14.PMID: 16160866 [PubMed - indexed for MEDLINE]Related articles

Evidence for a mitochondrial regulatory pathway defined by peroxisome proliferator-activated receptor-gamma coactivator-1 alpha, estrogen-related receptor-alpha, and mitofusin 2.

Soriano FX, Liesa M, Bach D, Chan DC, Palacín M, Zorzano A.

Diabetes. 2006 Jun;55(6):1783-91.PMID: 16731843 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes.

Ducluzeau PH, Perretti N, Laville M, Andreelli F, Vega N, Riou JP, Vidal H.

Diabetes. 2001 May;50(5):1134-42.PMID: 11334418 [PubMed - indexed for MEDLINE]Related articlesFree article

PPAR-gamma gene expression is elevated in skeletal muscle of obese and type II diabetic subjects.

Park KS, Ciaraldi TP, Abrams-Carter L, Mudaliar S, Nikoulina SE, Henry RR.

Diabetes. 1997 Jul;46(7):1230-4.PMID: 9200661 [PubMed - indexed for MEDLINE]Related articles

Suppressor of cytokine signaling 3 expression and insulin resistance in skeletal muscle of obese and type 2 diabetic patients.

Rieusset J, Bouzakri K, Chevillotte E, Ricard N, Jacquet D, Bastard JP, Laville M, Vidal H.

Diabetes. 2004 Sep;53(9):2232-41.PMID: 15331532 [PubMed - indexed for MEDLINE]Related articlesFree article

Upregulation of peroxisome proliferator-activated receptor gamma coactivator gene (PGC1A) during weight loss is related to insulin sensitivity but not to energy expenditure.

Gastaldi G, Russell A, Golay A, Giacobino JP, Habicht F, Barthassat V, Muzzin P, Bobbioni-Harsch E.

Diabetologia. 2007 Nov;50(11):2348-55. Epub 2007 Sep 8.PMID: 17828388 [PubMed - indexed for MEDLINE]Related articles

Expression of mRNAs encoding uncoupling proteins in human skeletal muscle: effects of obesity and diabetes.

Bao S, Kennedy A, Wojciechowski B, Wallace P, Ganaway E, Garvey WT.

Diabetes. 1998 Dec;47(12):1935-40.PMID: 9836527 [PubMed - indexed for MEDLINE]Related articlesFree article

Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-alpha.

Sewter C, Berger D, Considine RV, Medina G, Rochford J, Ciaraldi T, Henry R, Dohm L, Flier JS, O'Rahilly S, Vidal-Puig AJ.

Diabetes. 2002 Apr;51(4):1035-41.PMID: 11916923 [PubMed - indexed for MEDLINE]Related articlesFree article

The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system.

Pich S, Bach D, Briones P, Liesa M, Camps M, Testar X, Palacín M, Zorzano A.

Hum Mol Genet. 2005 Jun 1;14(11):1405-15. Epub 2005 Apr 13.PMID: 15829499 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal muscle triglycerides lowering is associated with net improvement of insulin sensitivity, TNF-alpha reduction and GLUT4 expression enhancement.

Mingrone G, Rosa G, Di Rocco P, Manco M, Capristo E, Castagneto M, Vettor R, Gasbarrini G, Greco AV.

Int J Obes Relat Metab Disord. 2002 Sep;26(9):1165-72.PMID: 12187392 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of weight reduction on skeletal muscle UCP2 and UCP3 mRNA expression and UCP3 protein content in Type II diabetic subjects.

Schrauwen P, Schaart G, Saris WH, Slieker LJ, Glatz JF, Vidal H, Blaak EE.

Diabetologia. 2000 Nov;43(11):1408-16.PMID: 11126411 [PubMed - indexed for MEDLINE]Related articles

Expression pattern of tumour necrosis factor receptors in subcutaneous and omental human adipose tissue: role of obesity and non-insulin-dependent diabetes mellitus.

Hube F, Birgel M, Lee YM, Hauner H.

Eur J Clin Invest. 1999 Aug;29(8):672-8.PMID: 10457150 [PubMed - indexed for MEDLINE]Related articles

Relationship between plasma free fatty acids and uncoupling protein-3 gene expression in skeletal muscle of obese subjects: in vitro evidence of a causal link.

Sbraccia P, D'Adamo M, Leonetti F, Buongiorno A, Silecchia G, Basso MS, Tamburrano G, Lauro D, Federici M, Di Daniele N, Lauro R.

Clin Endocrinol (Oxf). 2002 Aug;57(2):199-207.PMID: 12153598 [PubMed - indexed for MEDLINE]Related articles

The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase.

Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB.

J Clin Invest. 1995 May;95(5):2111-9.PMID: 7738178 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial dynamics as a bridge between mitochondrial dysfunction and insulin resistance.

Zorzano A, Liesa M, Palacín M.

Arch Physiol Biochem. 2009 Feb;115(1):1-12. Review.PMID: 19267277 [PubMed - indexed for MEDLINE]Related articles

Fatty acid transport protein-1 mRNA expression in skeletal muscle and in adipose tissue in humans.

Binnert C, Koistinen HA, Martin G, Andreelli F, Ebeling P, Koivisto VA, Laville M, Auwerx J, Vidal H.

Am J Physiol Endocrinol Metab. 2000 Nov;279(5):E1072-9.PMID: 11052962 [PubMed - indexed for MEDLINE]Related articlesFree article

Genes involved in mitochondrial biogenesis/function are induced in response to bilio-pancreatic diversion in morbidly obese individuals with normal glucose tolerance but not in type 2 diabetic patients.

Hernández-Alvarez MI, Chiellini C, Manco M, Naon D, Liesa M, Palacín M, Mingrone G, Zorzano A.

Diabetologia. 2009 Aug;52(8):1618-27. Epub 2009 Jun 6.PMID: 19504086 [PubMed - indexed for MEDLINE]Related articles