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    Results: 1 to 20 of 322

    1.

    Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability.

    Tremblay F, Krebs M, Dombrowski L, Brehm A, Bernroider E, Roth E, Nowotny P, Waldhäusl W, Marette A, Roden M.

    Diabetes. 2005 Sep;54(9):2674-84.PMID: 16123357 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    The Mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man.

    Krebs M, Brunmair B, Brehm A, Artwohl M, Szendroedi J, Nowotny P, Roth E, Fürnsinn C, Promintzer M, Anderwald C, Bischof M, Roden M.

    Diabetes. 2007 Jun;56(6):1600-7. Epub 2007 Feb 28.PMID: 17329620 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Unlike insulin, amino acids stimulate p70S6K but not GSK-3 or glycogen synthase in human skeletal muscle.

    Liu Z, Wu Y, Nicklas EW, Jahn LA, Price WJ, Barrett EJ.

    Am J Physiol Endocrinol Metab. 2004 Apr;286(4):E523-8. Epub 2003 Dec 2.PMID: 14656717 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Evidence against a role for insulin-signaling proteins PI 3-kinase and Akt in insulin resistance in human skeletal muscle induced by short-term GH infusion.

    Jessen N, Djurhuus CB, Jørgensen JO, Jensen LS, Møller N, Lund S, Schmitz O.

    Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E194-9. Epub 2004 Aug 31.PMID: 15339744 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Fatty acid-induced insulin resistance: decreased muscle PI3K activation but unchanged Akt phosphorylation.

    Kruszynska YT, Worrall DS, Ofrecio J, Frias JP, Macaraeg G, Olefsky JM.

    J Clin Endocrinol Metab. 2002 Jan;87(1):226-34.PMID: 11788651 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Amino acid- and lipid-induced insulin resistance in rat heart: molecular mechanisms.

    Terruzzi I, Allibardi S, Bendinelli P, Maroni P, Piccoletti R, Vesco F, Samaja M, Luzi L.

    Mol Cell Endocrinol. 2002 Apr 25;190(1-2):135-45.PMID: 11997187 [PubMed - indexed for MEDLINE]Related articles

    7.

    Amino acids do not alter the insulin-induced activation of the insulin signaling pathway in neonatal pigs.

    Suryawan A, O'Connor PM, Kimball SR, Bush JA, Nguyen HV, Jefferson LS, Davis TA.

    J Nutr. 2004 Jan;134(1):24-30.PMID: 14704288 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Mechanism of amino acid-induced skeletal muscle insulin resistance in humans.

    Krebs M, Krssak M, Bernroider E, Anderwald C, Brehm A, Meyerspeer M, Nowotny P, Roth E, Waldhäusl W, Roden M.

    Diabetes. 2002 Mar;51(3):599-605.PMID: 11872656 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Increased hexosamine availability similarly impairs the action of insulin and IGF-1 on glucose disposal.

    Hawkins M, Barzilai N, Chen W, Angelov I, Hu M, Cohen P, Rossetti L.

    Diabetes. 1996 Dec;45(12):1734-43.PMID: 8922359 [PubMed - indexed for MEDLINE]Related articles

    10.

    Fed-state clamp stimulates cellular mechanisms of muscle protein anabolism and modulates glucose disposal in normal men.

    Adegoke OA, Chevalier S, Morais JA, Gougeon R, Kimball SR, Jefferson LS, Wing SS, Marliss EB.

    Am J Physiol Endocrinol Metab. 2009 Jan;296(1):E105-13. Epub 2008 Oct 28.PMID: 18957614 [PubMed - indexed for MEDLINE]Related articles

    11.

    Decreased susceptibility to fatty acid-induced peripheral tissue insulin resistance in women.

    Frias JP, Macaraeg GB, Ofrecio J, Yu JG, Olefsky JM, Kruszynska YT.

    Diabetes. 2001 Jun;50(6):1344-50.PMID: 11375335 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Effects of amino acids on glucose disposal.

    Boden G, Tappy L.

    Diabetes. 1990 Sep;39(9):1079-84.PMID: 1974539 [PubMed - indexed for MEDLINE]Related articles

    13.

    Role of the glucosamine pathway in fat-induced insulin resistance.

    Hawkins M, Barzilai N, Liu R, Hu M, Chen W, Rossetti L.

    J Clin Invest. 1997 May 1;99(9):2173-82.PMID: 9151789 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake.

    Green CJ, Göransson O, Kular GS, Leslie NR, Gray A, Alessi DR, Sakamoto K, Hundal HS.

    J Biol Chem. 2008 Oct 10;283(41):27653-67. Epub 2008 Jul 31.PMID: 18669636 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Dose-response effect of elevated plasma free fatty acid on insulin signaling.

    Belfort R, Mandarino L, Kashyap S, Wirfel K, Pratipanawatr T, Berria R, Defronzo RA, Cusi K.

    Diabetes. 2005 Jun;54(6):1640-8.PMID: 15919784 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Exposure to TNF-alpha but not IL-1beta impairs insulin-dependent phosphorylation of protein kinase B and p70S6k in mouse C2C12 myogenic cells.

    Grzelkowska-Kowalczyk K, Wieteska-Skrzeczyńska W.

    Pol J Vet Sci. 2006;9(1):1-10.PMID: 16573269 [PubMed - indexed for MEDLINE]Related articles

    17.

    Resistance exercise decreases eIF2Bepsilon phosphorylation and potentiates the feeding-induced stimulation of p70S6K1 and rpS6 in young men.

    Glover EI, Oates BR, Tang JE, Moore DR, Tarnopolsky MA, Phillips SM.

    Am J Physiol Regul Integr Comp Physiol. 2008 Aug;295(2):R604-10. Epub 2008 Jun 18.PMID: 18565837 [PubMed - indexed for MEDLINE]Related articles

    18.

    In human endothelial cells amino acids inhibit insulin-induced Akt and ERK1/2 phosphorylation by an mTOR-dependent mechanism.

    Pellegatta F, Catapano AL, Luzi L, Terruzzi I.

    J Cardiovasc Pharmacol. 2006 May;47(5):643-9.PMID: 16775502 [PubMed - indexed for MEDLINE]Related articles

    19.

    Physiological hyperinsulinemia impairs insulin-stimulated glycogen synthase activity and glycogen synthesis.

    Iozzo P, Pratipanawatr T, Pijl H, Vogt C, Kumar V, Pipek R, Matsuda M, Mandarino LJ, Cusi KJ, DeFronzo RA.

    Am J Physiol Endocrinol Metab. 2001 May;280(5):E712-9.PMID: 11287353 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Differential effects of palmitate and palmitoleate on insulin action and glucose utilization in rat L6 skeletal muscle cells.

    Dimopoulos N, Watson M, Sakamoto K, Hundal HS.

    Biochem J. 2006 Nov 1;399(3):473-81.PMID: 16822230 [PubMed - indexed for MEDLINE]Related articlesFree article

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