PubMed

Type 2 diabetes causes remodeling of cerebrovasculature via differential regulation of matrix metalloproteinases and collagen synthesis: role of endothelin-1.

Harris AK, Hutchinson JR, Sachidanandam K, Johnson MH, Dorrance AM, Stepp DW, Fagan SC, Ergul A.

Diabetes. 2005 Sep;54(9):2638-44.PMID: 16123352 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for vasculoprotective effects of ETB receptors in resistance artery remodeling in diabetes.

Sachidanandam K, Portik-Dobos V, Harris AK, Hutchinson JR, Muller E, Johnson MH, Ergul A.

Diabetes. 2007 Nov;56(11):2753-8. Epub 2007 Aug 1.PMID: 17670915 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycemic control prevents microvascular remodeling and increased tone in type 2 diabetes: link to endothelin-1.

Sachidanandam K, Hutchinson JR, Elgebaly MM, Mezzetti EM, Dorrance AM, Motamed K, Ergul A.

Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R952-9. Epub 2009 Jan 28.PMID: 19176890 [PubMed - indexed for MEDLINE]Related articles

Type-2 diabetes-induced changes in vascular extracellular matrix gene expression: relation to vessel size.

Song W, Ergul A.

Cardiovasc Diabetol. 2006 Feb 17;5:3.PMID: 16503991 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of chronic endothelin receptor antagonism on cerebrovascular function in type 2 diabetes.

Harris AK, Elgebaly MM, Li W, Sachidanandam K, Ergul A.

Am J Physiol Regul Integr Comp Physiol. 2008 Apr;294(4):R1213-9. Epub 2008 Feb 20.PMID: 18287215 [PubMed - indexed for MEDLINE]Related articles

Endothelin antagonism prevents early EGFR transactivation but not increased matrix metalloproteinase activity in diabetes.

Portik-Dobos V, Harris AK, Song W, Hutchinson J, Johnson MH, Imig JD, Pollock DM, Ergul A.

Am J Physiol Regul Integr Comp Physiol. 2006 Feb;290(2):R435-41. Epub 2005 Oct 20.PMID: 16239374 [PubMed - indexed for MEDLINE]Related articles

Effect of chronic and selective endothelin receptor antagonism on microvascular function in type 2 diabetes.

Sachidanandam K, Elgebaly MM, Harris AK, Hutchinson JR, Mezzetti EM, Portik-Dobos V, Ergul A.

Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2743-9. Epub 2008 Apr 18.PMID: 18424628 [PubMed - indexed for MEDLINE]Related articlesFree article

Stress upregulates arterial matrix metalloproteinase expression and activity via endothelin A receptor activation.

Ergul A, Portik-Dobos V, Giulumian AD, Molero MM, Fuchs LC.

Am J Physiol Heart Circ Physiol. 2003 Nov;285(5):H2225-32. Epub 2003 Jul 3.PMID: 12842810 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of ET(A) and ET(B) receptor antagonism on oxidative stress in type 2 diabetes.

Elgebaly MM, Portik-Dobos V, Sachidanandam K, Rychly D, Malcom D, Johnson MH, Ergul A.

Vascul Pharmacol. 2007 Aug-Sep;47(2-3):125-30. Epub 2007 Jun 6.PMID: 17597010 [PubMed - indexed for MEDLINE]Related articles

Differential effects of diet-induced dyslipidemia and hyperglycemia on mesenteric resistance artery structure and function in type 2 diabetes.

Sachidanandam K, Hutchinson JR, Elgebaly MM, Mezzetti EM, Wang MH, Ergul A.

J Pharmacol Exp Ther. 2009 Jan;328(1):123-30. Epub 2008 Oct 21.PMID: 18941121 [PubMed - indexed for MEDLINE]Related articles

Effects of nonselective endothelin-1 receptor antagonism on cardiac mast cell-mediated ventricular remodeling in rats.

Murray DB, Gardner JD, Brower GL, Janicki JS.

Am J Physiol Heart Circ Physiol. 2008 Mar;294(3):H1251-7. Epub 2008 Jan 4.PMID: 18178727 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelin-1 mediated regulation of extracellular matrix collagens in cells of human lamina cribrosa.

Rao VR, Krishnamoorthy RR, Yorio T.

Exp Eye Res. 2008 Jun;86(6):886-94. Epub 2008 Mar 12.PMID: 18420197 [PubMed - indexed for MEDLINE]Related articlesFree article

Microvascular versus macrovascular dysfunction in type 2 diabetes: differences in contractile responses to endothelin-1.

Sachidanandam K, Harris A, Hutchinson J, Ergul A.

Exp Biol Med (Maywood). 2006 Jun;231(6):1016-21.PMID: 16741041 [PubMed - indexed for MEDLINE]Related articlesFree article

Fibrosis, matrix metalloproteinases, and inflammation in the heart of DOCA-salt hypertensive rats: role of ET(A) receptors.

Ammarguellat FZ, Gannon PO, Amiri F, Schiffrin EL.

Hypertension. 2002 Feb;39(2 Pt 2):679-84.PMID: 11882630 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of dual endothelin receptor antagonist on antiapoptotic marker Bcl-2 expression in streptozotocin-induced diabetic rats.

Jesmin S, Zaedi S, Yamaguchi N, Maeda S, Yamaguchi I, Goto K, Miyauchi T.

Exp Biol Med (Maywood). 2006 Jun;231(6):1034-9.PMID: 16741044 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for a matrix metalloproteinase induction/activation system in arterial vasculature and decreased synthesis and activity in diabetes.

Portik-Dobos V, Anstadt MP, Hutchinson J, Bannan M, Ergul A.

Diabetes. 2002 Oct;51(10):3063-8.PMID: 12351448 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelin-1-mediated signaling in the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in astrocytes.

He S, Prasanna G, Yorio T.

Invest Ophthalmol Vis Sci. 2007 Aug;48(8):3737-45.PMID: 17652746 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelin-mediated remodeling in aortas of diabetic rats.

Fukuda G, Khan ZA, Barbin YP, Farhangkhoee H, Tilton RG, Chakrabarti S.

Diabetes Metab Res Rev. 2005 Jul-Aug;21(4):367-75.PMID: 15580650 [PubMed - indexed for MEDLINE]Related articles

Angiotensin II and endothelin-1 augment the vascular complications of diabetes via JAK2 activation.

Banes-Berceli AK, Ketsawatsomkron P, Ogbi S, Patel B, Pollock DM, Marrero MB.

Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H1291-9. Epub 2007 May 25.PMID: 17526654 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelin-1 is a potent stimulator of alpha1beta1 integrin-mediated collagen matrix remodeling by rat mesangial cells.

Kitamura A, Kagami S, Urushihara M, Kondo S, Yoshizumi M, Tamaki T, Kuroda Y.

Biochem Biophys Res Commun. 2002 Dec 13;299(4):555-61.PMID: 12459174 [PubMed - indexed for MEDLINE]Related articles