PubMed

Matrix metalloproteinases contribute to insulin insufficiency in Zucker diabetic fatty rats.

Zhou YP, Madjidi A, Wilson ME, Nothhelfer DA, Johnson JH, Palma JF, Schweitzer A, Burant C, Blume JE, Johnson JD.

Diabetes. 2005 Sep;54(9):2612-9.PMID: 16123349 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet microvasculature in islet hyperplasia and failure in a model of type 2 diabetes.

Li X, Zhang L, Meshinchi S, Dias-Leme C, Raffin D, Johnson JD, Treutelaar MK, Burant CF.

Diabetes. 2006 Nov;55(11):2965-73.PMID: 17065332 [PubMed - indexed for MEDLINE]Related articlesFree article

Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat.

Tokuyama Y, Sturis J, DePaoli AM, Takeda J, Stoffel M, Tang J, Sun X, Polonsky KS, Bell GI.

Diabetes. 1995 Dec;44(12):1447-57.PMID: 7589853 [PubMed - indexed for MEDLINE]Related articles

Modulation of adipoinsular axis in prediabetic zucker diabetic fatty rats by diazoxide.

Alemzadeh R, Tushaus KM.

Endocrinology. 2004 Dec;145(12):5476-84. Epub 2004 Aug 19.PMID: 15319354 [PubMed - indexed for MEDLINE]Related articlesFree article

Phlorizin treatment prevents the decrease in plasma insulin levels but not the progressive histopathological changes in the pancreatic islets during aging of Zucker diabetic fatty rats.

Janssen SW, Martens GJ, Sweep CG, Span PN, Verhofstad AA, Hermus AR.

J Endocrinol Invest. 2003 Jun;26(6):508-15.PMID: 12952363 [PubMed - indexed for MEDLINE]Related articles

Changes in pancreatic islet glucokinase and hexokinase activities with increasing age, obesity, and the onset of diabetes.

Cockburn BN, Ostrega DM, Sturis J, Kubstrup C, Polonsky KS, Bell GI.

Diabetes. 1997 Sep;46(9):1434-9.PMID: 9287043 [PubMed - indexed for MEDLINE]Related articles

Analysis of gene expression profiles in insulin-sensitive tissues from pre-diabetic and diabetic Zucker diabetic fatty rats.

Suh YH, Kim Y, Bang JH, Choi KS, Lee JW, Kim WH, Oh TJ, An S, Jung MH.

J Mol Endocrinol. 2005 Apr;34(2):299-315.PMID: 15821098 [PubMed - indexed for MEDLINE]Related articlesFree article

Antecedent hyperglycemia, not hyperlipidemia, is associated with increased islet triacylglycerol content and decreased insulin gene mRNA level in Zucker diabetic fatty rats.

Harmon JS, Gleason CE, Tanaka Y, Poitout V, Robertson RP.

Diabetes. 2001 Nov;50(11):2481-6.PMID: 11679425 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential gene expression between Zucker Fatty rats and Zucker Diabetic Fatty rats: a potential role for the immediate-early gene Egr-1 in regulation of beta cell proliferation.

Garnett KE, Chapman P, Chambers JA, Waddell ID, Boam DS.

J Mol Endocrinol. 2005 Aug;35(1):13-25.PMID: 16087718 [PubMed - indexed for MEDLINE]Related articlesFree article

Progressive histopathological changes in pancreatic islets of Zucker Diabetic Fatty rats.

Janssen SW, Hermus AR, Lange WP, Knijnenburg Q, van der Laak JA, Sweep CG, Martens GJ, Verhofstad AA.

Exp Clin Endocrinol Diabetes. 2001;109(5):273-82.PMID: 11507651 [PubMed - indexed for MEDLINE]Related articles

Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes.

Gram DX, Ahrén B, Nagy I, Olsen UB, Brand CL, Sundler F, Tabanera R, Svendsen O, Carr RD, Santha P, Wierup N, Hansen AJ.

Eur J Neurosci. 2007 Jan;25(1):213-23.PMID: 17241282 [PubMed - indexed for MEDLINE]Related articles

Prevention of hyperglycemia in Zucker diabetic fatty rats by exercise training: effects on gene expression in insulin-sensitive tissues determined by high-density oligonucleotide microarray analysis.

Colombo M, Gregersen S, Kruhoeffer M, Agger A, Xiao J, Jeppesen PB, Orntoft T, Ploug T, Galbo H, Hermansen K.

Metabolism. 2005 Dec;54(12):1571-81.PMID: 16311088 [PubMed - indexed for MEDLINE]Related articles

A genetic defect in beta-cell gene expression segregates independently from the fa locus in the ZDF rat.

Griffen SC, Wang J, German MS.

Diabetes. 2001 Jan;50(1):63-8.PMID: 11147796 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced de novo lipogenesis in the leptin-unresponsive pancreatic islets of prediabetic Zucker diabetic fatty rats: role in the pathogenesis of lipotoxic diabetes.

Zhou YT, Shimabukuro M, Lee Y, Koyama K, Higa M, Ferguson T, Unger RH.

Diabetes. 1998 Dec;47(12):1904-8.PMID: 9836522 [PubMed - indexed for MEDLINE]Related articlesFree article

Energy restriction prevents the development of type 2 diabetes in Zucker diabetic fatty rats: coordinated patterns of gene expression for energy metabolism in insulin-sensitive tissues and pancreatic islets determined by oligonucleotide microarray analysis.

Colombo M, Kruhoeffer M, Gregersen S, Agger A, Jeppesen P, Oerntoft T, Hermansen K.

Metabolism. 2006 Jan;55(1):43-52.PMID: 16324918 [PubMed - indexed for MEDLINE]Related articles

Improved islet morphology after blockade of the renin- angiotensin system in the ZDF rat.

Tikellis C, Wookey PJ, Candido R, Andrikopoulos S, Thomas MC, Cooper ME.

Diabetes. 2004 Apr;53(4):989-97.PMID: 15047614 [PubMed - indexed for MEDLINE]Related articlesFree article

Limited role for SREBP-1c in defective glucose-induced insulin secretion from Zucker diabetic fatty rat islets: a functional and gene profiling analysis.

Parton LE, McMillen PJ, Shen Y, Docherty E, Sharpe E, Diraison F, Briscoe CP, Rutter GA.

Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E982-94. Epub 2006 Jun 13.PMID: 16772326 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor (PPAR)-alpha agonism prevents the onset of type 2 diabetes in Zucker diabetic fatty rats: A comparison with PPAR gamma agonism.

Bergeron R, Yao J, Woods JW, Zycband EI, Liu C, Li Z, Adams A, Berger JP, Zhang BB, Moller DE, Doebber TW.

Endocrinology. 2006 Sep;147(9):4252-62. Epub 2006 May 25.PMID: 16728496 [PubMed - indexed for MEDLINE]Related articlesFree article

Differences in plasma homocysteine levels between Zucker fatty and Zucker diabetic fatty rats following 3 weeks oral administration of organic vanadium compounds.

Wasan KM, Risovic V, Yuen VG, McNeill JH.

J Trace Elem Med Biol. 2006;19(4):251-8. Epub 2005 Dec 13.PMID: 16443173 [PubMed - indexed for MEDLINE]Related articles

Attenuation of type 2 diabetes mellitus in the male Zucker diabetic fatty rat: the effects of stress and non-volitional exercise.

Király MA, Bates HE, Yue JT, Goche-Montes D, Fediuc S, Park E, Matthews SG, Vranic M, Riddell MC.

Metabolism. 2007 Jun;56(6):732-44.PMID: 17512304 [PubMed - indexed for MEDLINE]Related articles