PubMed

Combination therapy with epidermal growth factor and gastrin increases beta-cell mass and reverses hyperglycemia in diabetic NOD mice.

Suarez-Pinzon WL, Yan Y, Power R, Brand SJ, Rabinovitch A.

Diabetes. 2005 Sep;54(9):2596-601.PMID: 16123347 [PubMed - indexed for MEDLINE]Related articlesFree article

Combination therapy with epidermal growth factor and gastrin delays autoimmune diabetes recurrence in nonobese diabetic mice transplanted with syngeneic islets.

Suarez-Pinzon WL, Rabinovitch A.

Transplant Proc. 2008 Mar;40(2):529-32.PMID: 18374121 [PubMed - indexed for MEDLINE]Related articles

Combination therapy with glucagon-like peptide-1 and gastrin restores normoglycemia in diabetic NOD mice.

Suarez-Pinzon WL, Power RF, Yan Y, Wasserfall C, Atkinson M, Rabinovitch A.

Diabetes. 2008 Dec;57(12):3281-8. Epub 2008 Oct 3.PMID: 18835930 [PubMed - indexed for MEDLINE]Related articlesFree article

Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet {beta}-cells from pancreatic duct cells and an increase in functional {beta}-cell mass.

Suarez-Pinzon WL, Lakey JR, Brand SJ, Rabinovitch A.

J Clin Endocrinol Metab. 2005 Jun;90(6):3401-9. Epub 2005 Mar 15.PMID: 15769977 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacological treatment of chronic diabetes by stimulating pancreatic beta-cell regeneration with systemic co-administration of EGF and gastrin.

Brand SJ, Tagerud S, Lambert P, Magil SG, Tatarkiewicz K, Doiron K, Yan Y.

Pharmacol Toxicol. 2002 Dec;91(6):414-20. Review.PMID: 12688387 [PubMed - indexed for MEDLINE]Related articles

Combination therapy with glucagon-like peptide-1 and gastrin induces beta-cell neogenesis from pancreatic duct cells in human islets transplanted in immunodeficient diabetic mice.

Suarez-Pinzon WL, Lakey JR, Rabinovitch A.

Cell Transplant. 2008;17(6):631-40.PMID: 18819251 [PubMed - indexed for MEDLINE]Related articles

Persistence of residual beta cells and islet autoimmunity during increasing duration of diabetes in NOD mice and experimental approaches toward reversing new-onset disease with bioactive peptides.

Reddy S, Cheung CC, Chai RC, Rodrigues JA.

Ann N Y Acad Sci. 2008 Dec;1150:171-6.PMID: 19120289 [PubMed - indexed for MEDLINE]Related articles

Combined gastrin and epidermal growth factor treatment induces islet regeneration and restores normoglycaemia in C57Bl6/J mice treated with alloxan.

Rooman I, Bouwens L.

Diabetologia. 2004 Feb;47(2):259-65. Epub 2003 Dec 10.PMID: 14666367 [PubMed - indexed for MEDLINE]Related articles

Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4.

Ogawa N, List JF, Habener JF, Maki T.

Diabetes. 2004 Jul;53(7):1700-5.PMID: 15220193 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversal of established autoimmune diabetes by restoration of endogenous beta cell function.

Ryu S, Kodama S, Ryu K, Schoenfeld DA, Faustman DL.

J Clin Invest. 2001 Jul;108(1):63-72.PMID: 11435458 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse.

Sreenan S, Pick AJ, Levisetti M, Baldwin AC, Pugh W, Polonsky KS.

Diabetes. 1999 May;48(5):989-96.PMID: 10331402 [PubMed - indexed for MEDLINE]Related articlesFree article

Blood glucose levels regulate pancreatic beta-cell proliferation during experimentally-induced and spontaneous autoimmune diabetes in mice.

Pechhold K, Koczwara K, Zhu X, Harrison VS, Walker G, Lee J, Harlan DM.

PLoS One. 2009;4(3):e4827. Epub 2009 Mar 16.PMID: 19287497 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship between beta cell mass of NOD donors and diabetes development of NOD-scid recipients in adoptive transfer system.

Yamada S, Shimada A, Kodama K, Morimoto J, Suzuki R, Oikawa Y, Irie J, Saruta T.

Ann N Y Acad Sci. 2003 Nov;1005:211-4.PMID: 14679061 [PubMed - indexed for MEDLINE]Related articles

Exendin-4 improves reversal of diabetes in NOD mice treated with anti-CD3 monoclonal antibody by enhancing recovery of beta-cells.

Sherry NA, Chen W, Kushner JA, Glandt M, Tang Q, Tsai S, Santamaria P, Bluestone JA, Brillantes AM, Herold KC.

Endocrinology. 2007 Nov;148(11):5136-44. Epub 2007 Aug 2.PMID: 17673522 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessment of beta cell mass and oxidative peritoneal exudate cells in murine type 1 diabetes using adoptive transfer system.

Yamada S, Irie J, Shimada A, Kodama K, Morimoto J, Suzuki R, Oikawa Y, Saruta T.

Autoimmunity. 2003 Mar;36(2):63-70.PMID: 12820687 [PubMed - indexed for MEDLINE]Related articles

Acceleration of the development of diabetes in obese diabetic (db/db) mice by nicotinamide: a comparison with its antidiabetic effects in non-obese diabetic mice.

Piercy V, Toseland CD, Turner NC.

Metabolism. 2000 Dec;49(12):1548-54.PMID: 11145115 [PubMed - indexed for MEDLINE]Related articles

Immunomodulation through inhibition of multiple adhesion molecules generates resistance to autoimmune diabetes in NOD mice.

Ninova D, Dean PG, Stegall MD.

J Autoimmun. 2004 Nov;23(3):201-9.PMID: 15501391 [PubMed - indexed for MEDLINE]Related articles

Regenerative and therapeutic effects of heparin-binding epidermal growth factor-like growth factor on diabetes by gene transduction through retrograde pancreatic duct injection of adenovirus vector.

Kozawa J, Tokui Y, Moriwaki M, Li M, Ohmoto H, Yuan M, Zhang J, Iwahashi H, Imagawa A, Yamagata K, Tochino Y, Shimomura I, Higashiyama S, Miyagawa J.

Pancreas. 2005 Jul;31(1):32-42.PMID: 15968245 [PubMed - indexed for MEDLINE]Related articles

Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice.

Tarbell KV, Petit L, Zuo X, Toy P, Luo X, Mqadmi A, Yang H, Suthanthiran M, Mojsov S, Steinman RM.

J Exp Med. 2007 Jan 22;204(1):191-201. Epub 2007 Jan 8.PMID: 17210729 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential role for signal transducer and activator of transcription-1 in pancreatic beta-cell death and autoimmune type 1 diabetes of nonobese diabetic mice.

Kim S, Kim HS, Chung KW, Oh SH, Yun JW, Im SH, Lee MK, Kim KW, Lee MS.

Diabetes. 2007 Oct;56(10):2561-8. Epub 2007 Jul 9.PMID: 17620422 [PubMed - indexed for MEDLINE]Related articlesFree article