PubMed

Interferon-alpha as a mediator of polyinosinic:polycytidylic acid-induced type 1 diabetes.

Devendra D, Jasinski J, Melanitou E, Nakayama M, Li M, Hensley B, Paronen J, Moriyama H, Miao D, Eisenbarth GS, Liu E.

Diabetes. 2005 Sep;54(9):2549-56.PMID: 16123342 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic differentiation of poly I:C from B:9-23 peptide induced experimental autoimmune diabetes.

Paronen J, Liu E, Moriyama H, Devendra D, Ide A, Taylor R, Yu L, Miao D, Melanitou E, Eisenbarth GS.

J Autoimmun. 2004 Jun;22(4):307-13.PMID: 15120754 [PubMed - indexed for MEDLINE]Related articles

Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic-polycytidylic acid) and an insulin self-peptide.

Moriyama H, Wen L, Abiru N, Liu E, Yu L, Miao D, Gianani R, Wong FS, Eisenbarth GS.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5539-44. Epub 2002 Apr 9.PMID: 11943868 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of innate immunity on autoimmune diabetes and the expression of Toll-like receptors on pancreatic islets.

Wen L, Peng J, Li Z, Wong FS.

J Immunol. 2004 Mar 1;172(5):3173-80.PMID: 14978124 [PubMed - indexed for MEDLINE]Related articlesFree article

Depletion of T cells by type I interferon: differences between young and aged mice.

Jiang J, Gross D, Nogusa S, Elbaum P, Murasko DM.

J Immunol. 2005 Aug 1;175(3):1820-6.PMID: 16034124 [PubMed - indexed for MEDLINE]Related articlesFree article

Interferon alpha--a potential link in the pathogenesis of viral-induced type 1 diabetes and autoimmunity.

Devendra D, Eisenbarth GS.

Clin Immunol. 2004 Jun;111(3):225-33. Review.PMID: 15183143 [PubMed - indexed for MEDLINE]Related articles

The adjuvant effects of the toll-like receptor 3 ligand polyinosinic-cytidylic acid poly (I:C) on antigen-specific CD8+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu.

Salem ML, El-Naggar SA, Kadima A, Gillanders WE, Cole DJ.

Vaccine. 2006 Jun 12;24(24):5119-32. Epub 2006 May 2.PMID: 16704888 [PubMed - indexed for MEDLINE]Related articles

IFN-alpha can both protect against and promote the development of type 1 diabetes.

Wong FS, Wen L.

Ann N Y Acad Sci. 2008 Dec;1150:187-9.PMID: 19120292 [PubMed - indexed for MEDLINE]Related articles

Induction of type I diabetes by interferon-alpha in transgenic mice.

Stewart TA, Hultgren B, Huang X, Pitts-Meek S, Hully J, MacLachlan NJ.

Science. 1993 Jun 25;260(5116):1942-6.PMID: 8100367 [PubMed - indexed for MEDLINE]Related articles

Islet expression of interferon-alpha precedes diabetes in both the BB rat and streptozotocin-treated mice.

Huang X, Hultgren B, Dybdal N, Stewart TA.

Immunity. 1994 Sep;1(6):469-78.PMID: 7895158 [PubMed - indexed for MEDLINE]Related articles

In vitro-generated viral double-stranded RNA in contrast to polyinosinic:polycytidylic acid induces interferon-alpha in human plasmacytoid dendritic cells.

Löseke S, Grage-Griebenow E, Heine H, Wagner A, Akira S, Bauer S, Bufe A.

Scand J Immunol. 2006 Apr;63(4):264-74.PMID: 16623926 [PubMed - indexed for MEDLINE]Related articles

Induction of potent and long-lasting CD4 and CD8 T-cell responses against hepatitis C virus by immunization with viral antigens plus poly(I:C) and anti-CD40.

Zabaleta A, Arribillaga L, Llopiz D, Dotor J, Lasarte JJ, Prieto J, Borrás-Cuesta F, Esteban JI, Quer J, Vayreda F, Sarobe P.

Antiviral Res. 2007 Apr;74(1):25-35. Epub 2007 Jan 22.PMID: 17275104 [PubMed - indexed for MEDLINE]Related articles

Combined insulin B:9-23 self-peptide and polyinosinic-polycytidylic acid accelerate insulitis but inhibit development of diabetes by increasing the proportion of CD4+Foxp3+ regulatory T cells in the islets in non-obese diabetic mice.

Fukushima K, Abiru N, Nagayama Y, Kobayashi M, Satoh T, Nakahara M, Kawasaki E, Yamasaki H, Ueha S, Matsushima K, Liu E, Eguchi K.

Biochem Biophys Res Commun. 2008 Mar 21;367(4):719-24. Epub 2008 Jan 14.PMID: 18194666 [PubMed - indexed for MEDLINE]Related articles

Immunoadjuvant effects of polyadenylic:polyuridylic acids through TLR3 and TLR7.

Sugiyama T, Hoshino K, Saito M, Yano T, Sasaki I, Yamazaki C, Akira S, Kaisho T.

Int Immunol. 2008 Jan;20(1):1-9. Epub 2007 Nov 1.PMID: 17981792 [PubMed - indexed for MEDLINE]Related articles

Differential responsiveness to interferon-alpha in beta-cells and non-beta cells.

Bonnevie-Nielsen V, Buschard K, Dyrberg T.

Diabetes. 1996 Jun;45(6):818-21.PMID: 8635659 [PubMed - indexed for MEDLINE]Related articles

Poly I:C induction of alpha-interferon in the diabetes-prone BB and normal Wistar rats. Dose-response relationships.

Sobel DO, Ewel CH, Zeligs B, Abbassi V, Rossio J, Bellanti JA.

Diabetes. 1994 Apr;43(4):518-22.PMID: 8138055 [PubMed - indexed for MEDLINE]Related articles

In vivo and in vitro regulation of type I IFN synthesis by synergistic effects of CD40 and type II IFN.

Greene JA, DeVecchio JL, Gould MP, Auletta JJ, Heinzel FP.

J Immunol. 2006 May 15;176(10):5995-6003.PMID: 16670308 [PubMed - indexed for MEDLINE]Related articlesFree article

Synergistic benefit in inflammatory arthritis by targeting I kappaB kinase epsilon and interferon beta.

Corr M, Boyle DL, Ronacher L, Flores N, Firestein GS.

Ann Rheum Dis. 2009 Feb;68(2):257-63. Epub 2008 Jul 24.PMID: 18653628 [PubMed - indexed for MEDLINE]Related articles

Induction of innate immunity against herpes simplex virus type 2 infection via local delivery of Toll-like receptor ligands correlates with beta interferon production.

Gill N, Deacon PM, Lichty B, Mossman KL, Ashkar AA.

J Virol. 2006 Oct;80(20):9943-50.PMID: 17005672 [PubMed - indexed for MEDLINE]Related articlesFree article

CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs.

Shiow LR, Rosen DB, Brdicková N, Xu Y, An J, Lanier LL, Cyster JG, Matloubian M.

Nature. 2006 Mar 23;440(7083):540-4. Epub 2006 Mar 8.PMID: 16525420 [PubMed - indexed for MEDLINE]Related articles