PubMed

A large-scale association analysis of common variation of the HNF1alpha gene with type 2 diabetes in the U.K. Caucasian population.

Weedon MN, Owen KR, Shields B, Hitman G, Walker M, McCarthy MI, Hattersley AT, Frayling TM.

Diabetes. 2005 Aug;54(8):2487-91.PMID: 16046319 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of common variation in the HNF1alpha gene region with risk of type 2 diabetes.

Winckler W, Burtt NP, Holmkvist J, Cervin C, de Bakker PI, Sun M, Almgren P, Tuomi T, Gaudet D, Hudson TJ, Ardlie KG, Daly MJ, Hirschhorn JN, Altshuler D, Groop L.

Diabetes. 2005 Aug;54(8):2336-42.PMID: 16046299 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variants of the hepatocyte nuclear factor-4alpha P2 promoter are associated with type 2 diabetes in the U.K. population.

Weedon MN, Owen KR, Shields B, Hitman G, Walker M, McCarthy MI, Love-Gregory LD, Permutt MA, Hattersley AT, Frayling TM.

Diabetes. 2004 Nov;53(11):3002-6.PMID: 15504983 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of common polymorphisms in the HNF4alpha promoter on susceptibility to type 2 diabetes in the French Caucasian population.

Vaxillaire M, Dina C, Lobbens S, Dechaume A, Vasseur-Delannoy V, Helbecque N, Charpentier G, Froguel P.

Diabetologia. 2005 Mar;48(3):440-4. Epub 2005 Feb 25.PMID: 15735892 [PubMed - indexed for MEDLINE]Related articles

The hepatic nuclear factor-1alpha G319S variant is associated with early-onset type 2 diabetes in Canadian Oji-Cree.

Hegele RA, Cao H, Harris SB, Hanley AJ, Zinman B.

J Clin Endocrinol Metab. 1999 Mar;84(3):1077-82.PMID: 10084598 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes.

Bagwell AM, Bento JL, Mychaleckyj JC, Freedman BI, Langefeld CD, Bowden DW.

Diabetes. 2005 Apr;54(4):1185-90.PMID: 15793260 [PubMed - indexed for MEDLINE]Related articlesFree article

The private hepatocyte nuclear factor-1alpha G319S variant is associated with plasma lipoprotein variation in Canadian Oji-Cree.

Hegele RA, Cao H, Harris SB, Hanley AJ, Zinman B, Connelly PW.

Arterioscler Thromb Vasc Biol. 2000 Jan;20(1):217-22.PMID: 10634821 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular scanning analysis of hepatocyte nuclear factor 1alpha (TCF1) gene in typical familial type 2 diabetes in African Americans.

Elbein SC, Teng K, Eddings K, Hargrove D, Scroggin E.

Metabolism. 2000 Feb;49(2):280-4.PMID: 10690959 [PubMed - indexed for MEDLINE]Related articles

A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an ashkenazi jewish population.

Love-Gregory LD, Wasson J, Ma J, Jin CH, Glaser B, Suarez BK, Permutt MA.

Diabetes. 2004 Apr;53(4):1134-40.PMID: 15047632 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes.

Winckler W, Weedon MN, Graham RR, McCarroll SA, Purcell S, Almgren P, Tuomi T, Gaudet D, Boström KB, Walker M, Hitman G, Hattersley AT, McCarthy MI, Ardlie KG, Hirschhorn JN, Daly MJ, Frayling TM, Groop L, Altshuler D.

Diabetes. 2007 Mar;56(3):685-93.PMID: 17327436 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variations in the ALMS1 gene do not contribute to susceptibility to type 2 diabetes in a large white UK population.

Patel S, Minton JA, Weedon MN, Frayling TM, Ricketts C, Hitman GA, McCarthy MI, Hattersley AT, Walker M, Barrett TG.

Diabetologia. 2006 Jun;49(6):1209-13. Epub 2006 Apr 7.PMID: 16601972 [PubMed - indexed for MEDLINE]Related articles

Association testing of variants in the hepatocyte nuclear factor 4alpha gene with risk of type 2 diabetes in 7,883 people.

Winckler W, Graham RR, de Bakker PI, Sun M, Almgren P, Tuomi T, Gaudet D, Hudson TJ, Ardlie KG, Daly MJ, Hirschhorn JN, Groop L, Altshuler D.

Diabetes. 2005 Mar;54(3):886-92.PMID: 15734869 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of a common haplotype of hepatocyte nuclear factor 1alpha with type 2 diabetes in Chinese population.

Wang CR, Hu C, Zhang R, Fang QC, Ma XJ, Jia WP, Xiang KS.

Biomed Environ Sci. 2007 Feb;20(1):41-6.PMID: 17458140 [PubMed - indexed for MEDLINE]Related articles

P2 promoter variants of the hepatocyte nuclear factor 4alpha gene are associated with type 2 diabetes in Mexican Americans.

Lehman DM, Richardson DK, Jenkinson CP, Hunt KJ, Dyer TD, Leach RJ, Arya R, Abboud HE, Blangero J, Duggirala R, Stern MP.

Diabetes. 2007 Feb;56(2):513-7.PMID: 17259399 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population.

Freathy RM, Weedon MN, Shields B, Hitman GA, Walker M, McCarthy MI, Hattersley AT, Frayling TM.

JOP. 2006 May 9;7(3):295-302.PMID: 16685110 [PubMed - indexed for MEDLINE]Related articlesFree article

Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies.

Barroso I, Luan J, Wheeler E, Whittaker P, Wasson J, Zeggini E, Weedon MN, Hunt S, Venkatesh R, Frayling TM, Delgado M, Neuman RJ, Zhao J, Sherva R, Glaser B, Walker M, Hitman G, McCarthy MI, Hattersley AT, Permutt MA, Wareham NJ, Deloukas P.

Diabetes. 2008 Nov;57(11):3161-5. Epub 2008 Aug 26.PMID: 18728231 [PubMed - indexed for MEDLINE]Related articlesFree article

Systematic search for single nucleotide polymorphisms in the FOXC2 gene: the absence of evidence for the association of three frequent single nucleotide polymorphisms and four common haplotypes with Japanese type 2 diabetes.

Osawa H, Onuma H, Murakami A, Ochi M, Nishimiya T, Kato K, Shimizu I, Fujii Y, Ohashi J, Makino H.

Diabetes. 2003 Feb;52(2):562-7.PMID: 12540636 [PubMed - indexed for MEDLINE]Related articlesFree article

Linkage disequilibrium mapping of the replicated type 2 diabetes linkage signal on chromosome 1q.

Prokopenko I, Zeggini E, Hanson RL, Mitchell BD, Rayner NW, Akan P, Baier L, Das SK, Elliott KS, Fu M, Frayling TM, Groves CJ, Gwilliam R, Scott LJ, Voight BF, Hattersley AT, Hu C, Morris AD, Ng M, Palmer CN, Tello-Ruiz M, Vaxillaire M, Wang CR, Stein L, Chan J, Jia W, Froguel P, Elbein SC, Deloukas P, Bogardus C, Shuldiner AR, McCarthy MI; International Type 2 Diabetes 1q Consortium.

Diabetes. 2009 Jul;58(7):1704-9. Epub 2009 Apr 23.PMID: 19389826 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation in the hypoxia-inducible factor-1alpha gene is associated with type 2 diabetes in Japanese.

Yamada N, Horikawa Y, Oda N, Iizuka K, Shihara N, Kishi S, Takeda J.

J Clin Endocrinol Metab. 2005 Oct;90(10):5841-7. Epub 2005 Jul 26.PMID: 16046581 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatocyte nuclear factor-1alpha gene and non-insulin-dependent diabetes mellitus in the Japanese population.

Babaya N, Ikegami H, Kawaguchi Y, Fujisawa T, Nakagawa Y, Hamada Y, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Ono M, Yamada K, Shen GQ, Fukuda M, Ogihara T.

Acta Diabetol. 1998 Oct;35(3):150-3.PMID: 9840451 [PubMed - indexed for MEDLINE]Related articles