PubMed

Preconditioning the diabetic heart: the importance of Akt phosphorylation.

Tsang A, Hausenloy DJ, Mocanu MM, Carr RD, Yellon DM.

Diabetes. 2005 Aug;54(8):2360-4.PMID: 16046302 [PubMed - indexed for MEDLINE]Related articlesFree article

Ischemic preconditioning protects by activating prosurvival kinases at reperfusion.

Hausenloy DJ, Tsang A, Mocanu MM, Yellon DM.

Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H971-6. Epub 2004 Sep 9.PMID: 15358610 [PubMed - indexed for MEDLINE]Related articlesFree article

Cross-talk between the survival kinases during early reperfusion: its contribution to ischemic preconditioning.

Hausenloy DJ, Mocanu MM, Yellon DM.

Cardiovasc Res. 2004 Aug 1;63(2):305-12.PMID: 15249188 [PubMed - indexed for MEDLINE]Related articlesFree article

Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway.

Tsang A, Hausenloy DJ, Mocanu MM, Yellon DM.

Circ Res. 2004 Aug 6;95(3):230-2. Epub 2004 Jul 8.PMID: 15242972 [PubMed - indexed for MEDLINE]Related articlesFree article

Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening.

Bhamra GS, Hausenloy DJ, Davidson SM, Carr RD, Paiva M, Wynne AM, Mocanu MM, Yellon DM.

Basic Res Cardiol. 2008 May;103(3):274-84. Epub 2007 Dec 13.PMID: 18080084 [PubMed - indexed for MEDLINE]Related articles

Second window of protection following myocardial preconditioning: an essential role for PI3 kinase and p70S6 kinase.

Kis A, Yellon DM, Baxter GF.

J Mol Cell Cardiol. 2003 Sep;35(9):1063-71.PMID: 12967629 [PubMed - indexed for MEDLINE]Related articles

PTEN activity is modulated during ischemia and reperfusion: involvement in the induction and decay of preconditioning.

Cai Z, Semenza GL.

Circ Res. 2005 Dec 9;97(12):1351-9. Epub 2005 Nov 10.PMID: 16284183 [PubMed - indexed for MEDLINE]Related articlesFree article

PPAR-alpha activation protects the type 2 diabetic myocardium against ischemia-reperfusion injury: involvement of the PI3-Kinase/Akt and NO pathway.

Bulhak AA, Jung C, Ostenson CG, Lundberg JO, Sjöquist PO, Pernow J.

Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H719-27. Epub 2009 Jan 16.PMID: 19151258 [PubMed - indexed for MEDLINE]Related articles

Ischemia-reperfusion injury and cardioprotection: investigating PTEN, the phosphatase that negatively regulates PI3K, using a congenital model of PTEN haploinsufficiency.

Siddall HK, Warrell CE, Yellon DM, Mocanu MM.

Basic Res Cardiol. 2008 Nov;103(6):560-8. Epub 2008 Jul 5.PMID: 18604624 [PubMed - indexed for MEDLINE]Related articles

Pharmacological preconditioning with tumor necrosis factor-alpha activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase).

Lecour S, Suleman N, Deuchar GA, Somers S, Lacerda L, Huisamen B, Opie LH.

Circulation. 2005 Dec 20;112(25):3911-8. Epub 2005 Dec 12.PMID: 16344382 [PubMed - indexed for MEDLINE]Related articlesFree article

STAT signaling in ischemic heart: a role of STAT5A in ischemic preconditioning.

Yamaura G, Turoczi T, Yamamoto F, Siddqui MA, Maulik N, Das DK.

Am J Physiol Heart Circ Physiol. 2003 Aug;285(2):H476-82.PMID: 12860560 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling.

Jonassen AK, Sack MN, Mjøs OD, Yellon DM.

Circ Res. 2001 Dec 7;89(12):1191-8.PMID: 11739285 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential role of PI3K/Akt pathway in the infarct size limitation and antiarrhythmic protection in the rat heart.

Ravingerová T, Matejíková J, Neckár J, Andelová E, Kolár F.

Mol Cell Biochem. 2007 Mar;297(1-2):111-20. Epub 2006 Oct 3.PMID: 17016676 [PubMed - indexed for MEDLINE]Related articles

Reduced susceptibility to ischemia-induced arrhythmias in the preconditioned rat heart is independent of PI3-kinase/Akt.

RAVINGEROVA T, MATEJIKOVA J, PANCZA D, KOLAR F.

Physiol Res. 2009;58(3):443-7.PMID: 19627174 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardioprotection induced by hydrogen sulfide preconditioning involves activation of ERK and PI3K/Akt pathways.

Hu Y, Chen X, Pan TT, Neo KL, Lee SW, Khin ES, Moore PK, Bian JS.

Pflugers Arch. 2008 Jan;455(4):607-16. Epub 2007 Aug 1.PMID: 17674030 [PubMed - indexed for MEDLINE]Related articles

Ischaemic preconditioning does not protect the heart in obese and lean animal models of type 2 diabetes.

Kristiansen SB, Løfgren B, Støttrup NB, Khatir D, Nielsen-Kudsk JE, Nielsen TT, Bøtker HE, Flyvbjerg A.

Diabetologia. 2004 Oct;47(10):1716-21. Epub 2004 Oct 7.PMID: 15480537 [PubMed - indexed for MEDLINE]Related articles

Ischemic postconditioning protects remodeled myocardium via the PI3K-PKB/Akt reperfusion injury salvage kinase pathway.

Zhu M, Feng J, Lucchinetti E, Fischer G, Xu L, Pedrazzini T, Schaub MC, Zaugg M.

Cardiovasc Res. 2006 Oct 1;72(1):152-62. Epub 2006 Jul 6.PMID: 16901477 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of ischaemic preconditioning in ovariectomized rat hearts: possible involvement of impaired protein kinase C epsilon phosphorylation.

Shinmura K, Nagai M, Tamaki K, Bolli R.

Cardiovasc Res. 2008 Aug 1;79(3):387-94. Epub 2008 Apr 4.PMID: 18390563 [PubMed - indexed for MEDLINE]Related articlesFree article

Src tyrosine kinase is the trigger but not the mediator of ischemic preconditioning.

Hattori R, Otani H, Uchiyama T, Imamura H, Cui J, Maulik N, Cordis GA, Zhu L, Das DK.

Am J Physiol Heart Circ Physiol. 2001 Sep;281(3):H1066-74.PMID: 11514272 [PubMed - indexed for MEDLINE]Related articlesFree article

Alpha-lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway.

Müller C, Dünschede F, Koch E, Vollmar AM, Kiemer AK.

Am J Physiol Gastrointest Liver Physiol. 2003 Oct;285(4):G769-78. Epub 2003 Jun 19.PMID: 12816756 [PubMed - indexed for MEDLINE]Related articlesFree article