PubMed

Proopiomelanocortin-deficient mice are hypersensitive to the adverse metabolic effects of glucocorticoids.

Coll AP, Challis BG, López M, Piper S, Yeo GS, O'Rahilly S.

Diabetes. 2005 Aug;54(8):2269-76.PMID: 16046291 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral mechanisms contributing to the glucocorticoid hypersensitivity in proopiomelanocortin null mice treated with corticosterone.

Michailidou Z, Coll AP, Kenyon CJ, Morton NM, O'Rahilly S, Seckl JR, Chapman KE.

J Endocrinol. 2007 Jul;194(1):161-70.PMID: 17592030 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo evidence for inverse agonism of Agouti-related peptide in the central nervous system of proopiomelanocortin-deficient mice.

Tolle V, Low MJ.

Diabetes. 2008 Jan;57(1):86-94. Epub 2007 Oct 1.PMID: 17909095 [PubMed - indexed for MEDLINE]Related articlesFree article

Attenuation of diabetic hyperphagia in neuropeptide Y--deficient mice.

Sindelar DK, Mystkowski P, Marsh DJ, Palmiter RD, Schwartz MW.

Diabetes. 2002 Mar;51(3):778-83.PMID: 11872679 [PubMed - indexed for MEDLINE]Related articlesFree article

Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice.

Makimura H, Mizuno TM, Roberts J, Silverstein J, Beasley J, Mobbs CV.

Diabetes. 2000 Nov;49(11):1917-23.PMID: 11078460 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of agouti-related protein on metabolism and hypothalamic neuropeptide gene expression.

Korner J, Wissig S, Kim A, Conwell IM, Wardlaw SL.

J Neuroendocrinol. 2003 Dec;15(12):1116-21.PMID: 14636173 [PubMed - indexed for MEDLINE]Related articles

11 beta-hydroxysteroid dehydrogenase type 1 induction in the arcuate nucleus by high-fat feeding: A novel constraint to hyperphagia?

Densmore VS, Morton NM, Mullins JJ, Seckl JR.

Endocrinology. 2006 Sep;147(9):4486-95. Epub 2006 Jun 8.PMID: 16763061 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific proopiomelanocortin-deficient mice.

Smart JL, Tolle V, Low MJ.

J Clin Invest. 2006 Feb;116(2):495-505. Epub 2006 Jan 26. Erratum in: J Clin Invest. 2006 Mar;116(3):842. PMID: 16440060 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral administration of the N-terminal pro-opiomelanocortin fragment 1-28 to Pomc-/- mice reduces food intake and weight but does not affect adrenal growth or corticosterone production.

Coll AP, Fassnacht M, Klammer S, Hahner S, Schulte DM, Piper S, Tung YC, Challis BG, Weinstein Y, Allolio B, O'Rahilly S, Beuschlein F.

J Endocrinol. 2006 Aug;190(2):515-25.PMID: 16899584 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of leptin and corticosterone on the expression of corticotropin-releasing hormone, agouti-related protein, and proopiomelanocortin in the brain of ob/ob mouse.

Arvaniti K, Huang Q, Richard D.

Neuroendocrinology. 2001 Apr;73(4):227-36.PMID: 11340336 [PubMed - indexed for MEDLINE]Related articles

Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression.

Makimura H, Mizuno TM, Isoda F, Beasley J, Silverstein JH, Mobbs CV.

BMC Physiol. 2003 Jul 9;3:5. Epub 2003 Jul 9.PMID: 12848900 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice.

Ziotopoulou M, Mantzoros CS, Hileman SM, Flier JS.

Am J Physiol Endocrinol Metab. 2000 Oct;279(4):E838-45.PMID: 11001766 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of adrenalectomy on AGRP, POMC, NPY and CART gene expression in the basal hypothalamus of fed and fasted rats.

Savontaus E, Conwell IM, Wardlaw SL.

Brain Res. 2002 Dec 20;958(1):130-8.PMID: 12468037 [PubMed - indexed for MEDLINE]Related articles

Effects of streptozotocin-induced diabetes and insulin treatment on the hypothalamic melanocortin system and muscle uncoupling protein 3 expression in rats.

Havel PJ, Hahn TM, Sindelar DK, Baskin DG, Dallman MF, Weigle DS, Schwartz MW.

Diabetes. 2000 Feb;49(2):244-52.PMID: 10868941 [PubMed - indexed for MEDLINE]Related articlesFree article

Age-dependent hypothalamic expression of neuropeptides in wild-type and melanocortin-4 receptor-deficient mice.

Arens J, Moar KM, Eiden S, Weide K, Schmidt I, Mercer JG, Simon E, Korf HW.

Physiol Genomics. 2003 Dec 16;16(1):38-46.PMID: 14559977 [PubMed - indexed for MEDLINE]Related articles

Hypothalamic pro-opiomelanocortin gene delivery ameliorates obesity and glucose intolerance in aged rats.

Li G, Zhang Y, Wilsey JT, Scarpace PJ.

Diabetologia. 2005 Nov;48(11):2376-85. Epub 2005 Oct 5.PMID: 16205885 [PubMed - indexed for MEDLINE]Related articles

Obesity in insulin receptor substrate-2-deficient mice: disrupted control of arcuate nucleus neuropeptides.

Masaki T, Chiba S, Noguchi H, Yasuda T, Tobe K, Suzuki R, Kadowaki T, Yoshimatsu H.

Obes Res. 2004 May;12(5):878-85.PMID: 15166310 [PubMed - indexed for MEDLINE]Related articles

Orexin expression is regulated by alpha-melanocyte-stimulating hormone.

López M, Lage R, Tung YC, Challis BG, Varela L, Virtue S, O'Rahilly S, Vidal-Puig A, Diéguez C, Coll AP.

J Neuroendocrinol. 2007 Sep;19(9):703-7.PMID: 17680885 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered levels of POMC, AgRP and MC4-R mRNA expression in the hypothalamus and other parts of the limbic system of mice prone or resistant to chronic high-energy diet-induced obesity.

Huang XF, Han M, South T, Storlien L.

Brain Res. 2003 Nov 28;992(1):9-19.PMID: 14604768 [PubMed - indexed for MEDLINE]Related articles

Pro-opiomelanocortin (POMC)-derived peptides and the regulation of energy homeostasis.

Coll AP, Loraine Tung YC.

Mol Cell Endocrinol. 2009 Mar 5;300(1-2):147-51. Epub 2008 Sep 17. Review.PMID: 18840502 [PubMed - indexed for MEDLINE]Related articles