PubMed

Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors.

Schermuly RT, Inholte C, Ghofrani HA, Gall H, Weissmann N, Weidenbach A, Seeger W, Grimminger F.

Respir Res. 2005 Jul 20;6:76.PMID: 16033645 [PubMed - indexed for MEDLINE]Related articlesFree article

Coaerosolization of phosphodiesterase inhibitors markedly enhances the pulmonary vasodilatory response to inhaled iloprost in experimental pulmonary hypertension. Maintenance of lung selectivity.

Schermuly RT, Krupnik E, Tenor H, Schudt C, Weissmann N, Rose F, Grimminger F, Seeger W, Walmrath D, Ghofrani HA.

Am J Respir Crit Care Med. 2001 Nov 1;164(9):1694-700.PMID: 11719312 [PubMed - indexed for MEDLINE]Related articlesFree article

Low-dose systemic phosphodiesterase inhibitors amplify the pulmonary vasodilatory response to inhaled prostacyclin in experimental pulmonary hypertension.

Schermuly RT, Ghofrani HA, Enke B, Weissmann N, Grimminger F, Seeger W, Schudt C, Walmrath D.

Am J Respir Crit Care Med. 1999 Nov;160(5 Pt 1):1500-6.PMID: 10556112 [PubMed - indexed for MEDLINE]Related articlesFree article

Subthreshold doses of specific phosphodiesterase type 3 and 4 inhibitors enhance the pulmonary vasodilatory response to nebulized prostacyclin with improvement in gas exchange.

Schermuly RT, Roehl A, Weissmann N, Ghofrani HA, Schudt C, Tenor H, Grimminger F, Seeger W, Walmrath D.

J Pharmacol Exp Ther. 2000 Feb;292(2):512-20.PMID: 10640287 [PubMed - indexed for MEDLINE]Related articlesFree article

Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension.

Ghofrani HA, Wiedemann R, Rose F, Olschewski H, Schermuly RT, Weissmann N, Seeger W, Grimminger F.

Ann Intern Med. 2002 Apr 2;136(7):515-22.PMID: 11926786 [PubMed - indexed for MEDLINE]Related articlesFree article

Amplification of the pulmonary vasodilatory response to inhaled iloprost by subthreshold phosphodiesterase types 3 and 4 inhibition in severe pulmonary hypertension.

Ghofrani HA, Rose F, Schermuly RT, Olschewski H, Wiedemann R, Weissmann N, Schudt C, Tenor H, Seeger W, Grimminger F.

Crit Care Med. 2002 Nov;30(11):2489-92.PMID: 12441759 [PubMed - indexed for MEDLINE]Related articles

Urodilatin, a natriuretic peptide stimulating particulate guanylate cyclase, and the phosphodiesterase 5 inhibitor dipyridamole attenuate experimental pulmonary hypertension: synergism upon coapplication.

Schermuly RT, Weissmann N, Enke B, Ghofrani HA, Forssmann WG, Grimminger F, Seeger W, Walmrath D.

Am J Respir Cell Mol Biol. 2001 Aug;25(2):219-25.PMID: 11509332 [PubMed - indexed for MEDLINE]Related articlesFree article

Zardaverine and aerosolised iloprost in a model of acute respiratory failure.

Schermuly RT, Leuchte H, Ghofrani HA, Weissmann N, Rose F, Kohstall M, Olschewski H, Schudt C, Grimminger F, Seeger W, Walmrath D.

Eur Respir J. 2003 Aug;22(2):342-7.PMID: 12952271 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of inhaled iloprost plus oral sildenafil in patients with primary pulmonary hypertension.

Wilkens H, Guth A, König J, Forestier N, Cremers B, Hennen B, Böhm M, Sybrecht GW.

Circulation. 2001 Sep 11;104(11):1218-22.PMID: 11551870 [PubMed - indexed for MEDLINE]Related articlesFree article

The additive pulmonary vasodilatory effects of inhaled prostacyclin and inhaled milrinone in postcardiac surgical patients with pulmonary hypertension.

Haraldsson s A, Kieler-Jensen N, Ricksten SE.

Anesth Analg. 2001 Dec;93(6):1439-45, table of contents.PMID: 11726420 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of pharmacokinetics and vasodilatory effect of nebulized and infused iloprost in experimental pulmonary hypertension: rapid tolerance development.

Schermuly RT, Schulz A, Ghofrani HA, Breitenbach CS, Weissmann N, Hildebrand M, Kurz J, Grimminger F, Seeger W.

J Aerosol Med. 2006 Fall;19(3):353-63.PMID: 17034310 [PubMed - indexed for MEDLINE]Related articles

Acute effects of the combination of sildenafil and inhaled treprostinil on haemodynamics and gas exchange in pulmonary hypertension.

Voswinckel R, Reichenberger F, Enke B, Kreckel A, Krick S, Gall H, Schermuly RT, Grimminger F, Rubin LJ, Olschewski H, Seeger W, Ghofrani HA.

Pulm Pharmacol Ther. 2008 Oct;21(5):824-32. Epub 2008 Jul 9.PMID: 18657627 [PubMed - indexed for MEDLINE]Related articles

Combination of nonspecific PDE inhibitors with inhaled prostacyclin in experimental pulmonary hypertension.

Schermuly RT, Roehl A, Weissmann N, Ghofrani HA, Leuchte H, Grimminger F, Seeger W, Walmrath D.

Am J Physiol Lung Cell Mol Physiol. 2001 Dec;281(6):L1361-8.PMID: 11704531 [PubMed - indexed for MEDLINE]Related articlesFree article

Hemodynamic response to sildenafil, nitric oxide, and iloprost in primary pulmonary hypertension.

Leuchte HH, Schwaiblmair M, Baumgartner RA, Neurohr CF, Kolbe T, Behr J.

Chest. 2004 Feb;125(2):580-6.PMID: 14769741 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of phosphodiesterase 1 augments the pulmonary vasodilator response to inhaled nitric oxide in awake lambs with acute pulmonary hypertension.

Evgenov OV, Busch CJ, Evgenov NV, Liu R, Petersen B, Falkowski GE, Petho B, Vas A, Bloch KD, Zapol WM, Ichinose F.

Am J Physiol Lung Cell Mol Physiol. 2006 Apr;290(4):L723-L729. Epub 2005 Nov 11.PMID: 16284211 [PubMed - indexed for MEDLINE]Related articlesFree article

Antiremodeling effects of iloprost and the dual-selective phosphodiesterase 3/4 inhibitor tolafentrine in chronic experimental pulmonary hypertension.

Schermuly RT, Kreisselmeier KP, Ghofrani HA, Samidurai A, Pullamsetti S, Weissmann N, Schudt C, Ermert L, Seeger W, Grimminger F.

Circ Res. 2004 Apr 30;94(8):1101-8. Epub 2004 Mar 18.PMID: 15031263 [PubMed - indexed for MEDLINE]Related articlesFree article

Iloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungs.

Schermuly RT, Pullamsetti SS, Breitenbach SC, Weissmann N, Ghofrani HA, Grimminger F, Nilius SM, Schrör K, Kirchrath JM, Seeger W, Rose F.

Respir Res. 2007 Jan 26;8:4.PMID: 17257398 [PubMed - indexed for MEDLINE]Related articlesFree article

Nebulized sildenafil is a selective pulmonary vasodilator in lambs with acute pulmonary hypertension.

Ichinose F, Erana-Garcia J, Hromi J, Raveh Y, Jones R, Krim L, Clark MW, Winkler JD, Bloch KD, Zapol WM.

Crit Care Med. 2001 May;29(5):1000-5.PMID: 11378612 [PubMed - indexed for MEDLINE]Related articles

Hypoxia-induced pulmonary hypertension: different impact of iloprost, sildenafil, and nitric oxide.

Weissmann N, Gerigk B, Kocer O, Nollen M, Hackemack S, Ghofrani HA, Schermuly RT, Butrous G, Schulz A, Roth M, Seeger W, Grimminger F.

Respir Med. 2007 Oct;101(10):2125-32. Epub 2007 Jul 20.PMID: 17643279 [PubMed - indexed for MEDLINE]Related articles

Low-dose phosphodiesterase inhibition improves responsiveness to inhaled nitric oxide in isolated lungs from endotoxemic rats.

Klein A, Zils U, Bopp C, Gries A, Martin E, Gust R.

J Surg Res. 2007 Apr;138(2):224-30. Epub 2007 Feb 1.PMID: 17275845 [PubMed - indexed for MEDLINE]Related articles