PubMed

Changes in P-glycoprotein activity are mediated by the growth of a tumour cell line as multicellular spheroids.

Ponce de León V, Barrera-Rodríguez R.

Cancer Cell Int. 2005 Jul 7;5(1):20.PMID: 16001980 [PubMed]Related articlesFree article

Inhibition of P-glycoprotein function by XR9576 in a solid tumour model can restore anticancer drug efficacy.

Walker J, Martin C, Callaghan R.

Eur J Cancer. 2004 Mar;40(4):594-605.PMID: 14962729 [PubMed - indexed for MEDLINE]Related articles

Development of an intrinsic P-glycoprotein-mediated doxorubicin resistance in quiescent cell layers of large, multicellular prostate tumor spheroids.

Wartenberg M, Frey C, Diedershagen H, Ritgen J, Hescheler J, Sauer H.

Int J Cancer. 1998 Mar 16;75(6):855-63.PMID: 9506530 [PubMed - indexed for MEDLINE]Related articles

Reactive oxygen species-linked regulation of the multidrug resistance transporter P-glycoprotein in Nox-1 overexpressing prostate tumor spheroids.

Wartenberg M, Hoffmann E, Schwindt H, Grünheck F, Petros J, Arnold JR, Hescheler J, Sauer H.

FEBS Lett. 2005 Aug 15;579(20):4541-4549.PMID: 16083877 [PubMed - indexed for MEDLINE]Related articles

Knock-down of P-glycoprotein reverses taxol resistance in ovarian cancer multicellular spheroids.

Xing H, Wang S, Weng D, Chen G, Yang X, Zhou J, Xu G, Lu Y, Ma D.

Oncol Rep. 2007 Jan;17(1):117-22.PMID: 17143487 [PubMed - indexed for MEDLINE]Related articles

Glycolytic pyruvate regulates P-Glycoprotein expression in multicellular tumor spheroids via modulation of the intracellular redox state.

Wartenberg M, Richter M, Datchev A, Günther S, Milosevic N, Bekhite MM, Figulla HR, Aran JM, Pétriz J, Sauer H.

J Cell Biochem. 2010 Feb 1;109(2):434-46.PMID: 19950199 [PubMed - in process]Related articles

[Resistance of multicellular spheroids to taxol in human ovarian cancer and its mechanism]

Xing H, Gao QL, Yang XK, Li J, Gao C, Wu JH, Lu YP, Ma D.

Ai Zheng. 2003 Aug;22(8):826-30. Chinese. PMID: 12917028 [PubMed - indexed for MEDLINE]Related articlesFree article

Resistance to verapamil sensitization of multidrug-resistant cells grown as multicellular spheroids.

Sakata K, Kwok TT, Gordon GR, Waleh NS, Sutherland RM.

Int J Cancer. 1994 Oct 15;59(2):282-6.PMID: 7927930 [PubMed - indexed for MEDLINE]Related articles

Effect of Stemona curtisii root extract on P-glycoprotein and MRP-1 function in multidrug-resistant cancer cells.

Limtrakul P, Siwanon S, Yodkeeree S, Duangrat C.

Phytomedicine. 2007 Jun;14(6):381-9. Epub 2007 Apr 30.PMID: 17467965 [PubMed - indexed for MEDLINE]Related articles

Bcl-2 family proteins contribute to apoptotic resistance in lung cancer multicellular spheroids.

Yang TM, Barbone D, Fennell DA, Broaddus VC.

Am J Respir Cell Mol Biol. 2009 Jul;41(1):14-23. Epub 2008 Dec 18.PMID: 19097992 [PubMed - indexed for MEDLINE]Related articles

Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.

Limtrakul P, Chearwae W, Shukla S, Phisalphong C, Ambudkar SV.

Mol Cell Biochem. 2007 Feb;296(1-2):85-95. Epub 2006 Sep 8.PMID: 16960658 [PubMed - indexed for MEDLINE]Related articles

Estrogen-mediated post transcriptional down-regulation of P-glycoprotein in MDR1-transduced human breast cancer cells.

Mutoh K, Tsukahara S, Mitsuhashi J, Katayama K, Sugimoto Y.

Cancer Sci. 2006 Nov;97(11):1198-204. Epub 2006 Aug 22.PMID: 16925584 [PubMed - indexed for MEDLINE]Related articles

ABCB1 and ABCG2 proteins, their functional activity and gene expression in concert with drug sensitivity of leukemia cells.

Svirnovski AI, Shman TV, Serhiyenka TF, Savitski VP, Smolnikova VV, Fedasenka UU.

Hematology. 2009 Aug;14(4):204-12.PMID: 19635183 [PubMed - indexed for MEDLINE]Related articles

Quinoline derivative KB3-1 potentiates paclitaxel induced cytotoxicity and cycle arrest via multidrug resistance reversal in MES-SA/DX5 cancer cells.

Koo JS, Choi WC, Rhee YH, Lee HJ, Lee EO, Ahn KS, Bae HS, Ahn KS, Kang JM, Choi SU, Kim MO, Lu J, Kim SH.

Life Sci. 2008 Nov 21;83(21-22):700-8. Epub 2008 Sep 24.PMID: 18845169 [PubMed - indexed for MEDLINE]Related articles

P-glycoprotein--implications of metabolism of neoplastic cells and cancer therapy.

Breier A, Barancík M, Sulová Z, Uhrík B.

Curr Cancer Drug Targets. 2005 Sep;5(6):457-68. Review.PMID: 16178819 [PubMed - indexed for MEDLINE]Related articles

Effect of pO2 on antitumor drug cytotoxicity on MDR and non-MDR variants selected from the LoVo metastatic colon carcinoma cell line.

Lelong-Rebel I, Brisson C, Fabre M, Bergerat JP, Rebel G.

Anticancer Res. 2008 Jan-Feb;28(1A):55-68.PMID: 18383825 [PubMed - indexed for MEDLINE]Related articles

P-glycoprotein enhances TRAIL-triggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor DR5.

Park SJ, Wu CH, Choi MR, Najafi F, Emami A, Safa AR.

Biochem Pharmacol. 2006 Jul 28;72(3):293-307. Epub 2006 May 4.PMID: 16753135 [PubMed - indexed for MEDLINE]Related articles

Sipholenol A, a marine-derived sipholane triterpene, potently reverses P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells.

Shi Z, Jain S, Kim IW, Peng XX, Abraham I, Youssef DT, Fu LW, El Sayed K, Ambudkar SV, Chen ZS.

Cancer Sci. 2007 Sep;98(9):1373-80. Epub 2007 Jul 19.PMID: 17640301 [PubMed - indexed for MEDLINE]Related articles

Combined treatment of P-gp-positive L1210/VCR cells by verapamil and all-trans retinoic acid induces down-regulation of P-glycoprotein expression and transport activity.

Sulová Z, Macejová D, Seres M, Sedlák J, Brtko J, Breier A.

Toxicol In Vitro. 2008 Feb;22(1):96-105. Epub 2007 Aug 31.PMID: 17920233 [PubMed - indexed for MEDLINE]Related articles

[Detection of metastatic activity of the MCF-7 multidrug resistant cell line cultured in spheroids]

Jardillier JC, Affoue M, Bobichon H, Delvincourt C, Madoulet C.

Bull Acad Natl Med. 1998;182(3):651-61; discussion 661-3. French. PMID: 9673058 [PubMed - indexed for MEDLINE]Related articles