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    Results: 1 to 20 of 827

    1.

    Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1 alpha in articular chondrocytes: involvement of HIF-1 alpha in the pathogenesis of osteoarthritis.

    Yudoh K, Nakamura H, Masuko-Hongo K, Kato T, Nishioka K.

    Arthritis Res Ther. 2005;7(4):R904-14. Epub 2005 May 27. Erratum in: Arthritis Res Ther. 2005;7(5):225.

    PMID:
    15987493
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Hypoxia inducible factor-1 alpha expression in human normal and osteoarthritic chondrocytes.

    Coimbra IB, Jimenez SA, Hawkins DF, Piera-Velazquez S, Stokes DG.

    Osteoarthritis Cartilage. 2004 Apr;12(4):336-45.

    PMID:
    15023385
    [PubMed - indexed for MEDLINE]
    3.

    Hypoxia-inducible factor 1alpha is involved in the prostaglandin metabolism of osteoarthritic cartilage through up-regulation of microsomal prostaglandin E synthase 1 in articular chondrocytes.

    Grimmer C, Pfander D, Swoboda B, Aigner T, Mueller L, Hennig FF, Gelse K.

    Arthritis Rheum. 2007 Dec;56(12):4084-94.

    PMID:
    18050215
    [PubMed - indexed for MEDLINE]
    Free Article
    4.

    Distinct signaling pathways are involved in hypoxia- and IL-1-induced VEGF expression in human articular chondrocytes.

    Murata M, Yudoh K, Nakamura H, Kato T, Inoue K, Chiba J, Nishioka K, Masuko-Hongo K.

    J Orthop Res. 2006 Jul;24(7):1544-54.

    PMID:
    16732616
    [PubMed - indexed for MEDLINE]
    6.

    Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function.

    Yudoh K, Nguyen T, Nakamura H, Hongo-Masuko K, Kato T, Nishioka K.

    Arthritis Res Ther. 2005;7(2):R380-91. Epub 2005 Jan 26.

    PMID:
    15743486
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    7.

    Role of hypoxia-inducible factor-1 alpha in the regulation of plasminogen activator activity in rat knee joint chondrocytes.

    Zhu G, Tang Y, Liang X, Zheng M, Yang J, Zhou H, Li L, Qin T.

    Osteoarthritis Cartilage. 2009 Nov;17(11):1494-502. Epub 2009 May 19.

    PMID:
    19490965
    [PubMed - indexed for MEDLINE]
    8.

    Water-soluble C60 fullerene prevents degeneration of articular cartilage in osteoarthritis via down-regulation of chondrocyte catabolic activity and inhibition of cartilage degeneration during disease development.

    Yudoh K, Shishido K, Murayama H, Yano M, Matsubayashi K, Takada H, Nakamura H, Masuko K, Kato T, Nishioka K.

    Arthritis Rheum. 2007 Oct;56(10):3307-18.

    PMID:
    17907184
    [PubMed - indexed for MEDLINE]
    Free Article
    9.

    Role of hypoxia-inducible factor 1 alpha in the integrity of articular cartilage in murine knee joints.

    Gelse K, Pfander D, Obier S, Knaup KX, Wiesener M, Hennig FF, Swoboda B.

    Arthritis Res Ther. 2008;10(5):R111. Epub 2008 Sep 12.

    PMID:
    18789153
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    Tonic activation of hypoxia-inducible factor 1alpha in avascular articular cartilage and implications for metabolic homeostasis.

    Brucker PU, Izzo NJ, Chu CR.

    Arthritis Rheum. 2005 Oct;52(10):3181-91.

    PMID:
    16200622
    [PubMed - indexed for MEDLINE]
    Free Article
    11.

    Effect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes.

    Martin G, Andriamanalijaona R, Grässel S, Dreier R, Mathy-Hartert M, Bogdanowicz P, Boumédiene K, Henrotin Y, Bruckner P, Pujol JP.

    Arthritis Rheum. 2004 Nov;50(11):3549-60.

    PMID:
    15529381
    [PubMed - indexed for MEDLINE]
    Free Article
    12.

    Hypoxia-inducible factor 2alpha is essential for hypoxic induction of the human articular chondrocyte phenotype.

    Lafont JE, Talma S, Murphy CL.

    Arthritis Rheum. 2007 Oct;56(10):3297-306.

    PMID:
    17907154
    [PubMed - indexed for MEDLINE]
    Free Article
    13.

    Hypoxia and HIF-1alpha in osteoarthritis.

    Pfander D, Cramer T, Swoboda B.

    Int Orthop. 2005 Feb;29(1):6-9. Epub 2004 Dec 21.

    PMID:
    15611874
    [PubMed - indexed for MEDLINE]
    14.

    Homeostasis of the extracellular matrix of normal and osteoarthritic human articular cartilage chondrocytes in vitro.

    Wang J, Verdonk P, Elewaut D, Veys EM, Verbruggen G.

    Osteoarthritis Cartilage. 2003 Nov;11(11):801-9.

    PMID:
    14609533
    [PubMed - indexed for MEDLINE]
    15.

    Haem oxygenase-1 regulates catabolic and anabolic processes in osteoarthritic chondrocytes.

    Guillén M, Megías J, Gomar F, Alcaraz M.

    J Pathol. 2008 Mar;214(4):515-22.

    PMID:
    18200630
    [PubMed - indexed for MEDLINE]
    16.

    Human meniscus cells express hypoxia inducible factor-1alpha and increased SOX9 in response to low oxygen tension in cell aggregate culture.

    Adesida AB, Grady LM, Khan WS, Millward-Sadler SJ, Salter DM, Hardingham TE.

    Arthritis Res Ther. 2007;9(4):R69.

    PMID:
    17640365
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Hypoxia and osteoarthritis: how chondrocytes survive hypoxic environments.

    Pfander D, Gelse K.

    Curr Opin Rheumatol. 2007 Sep;19(5):457-62. Review.

    PMID:
    17762611
    [PubMed - indexed for MEDLINE]
    18.

    Regulation of cytokine-induced HIF-1alpha expression in rheumatoid synovial fibroblasts.

    Westra J, Brouwer E, Bos R, Posthumus MD, Doornbos-van der Meer B, Kallenberg CG, Limburg PC.

    Ann N Y Acad Sci. 2007 Jun;1108:340-8.

    PMID:
    17893997
    [PubMed - indexed for MEDLINE]
    20.

    Calcium/calmodulin-dependent protein kinase II in human articular chondrocytes.

    Shimazaki A, Wright MO, Elliot K, Salter DM, Millward-Sadler SJ.

    Biorheology. 2006;43(3-4):223-33.

    PMID:
    16912396
    [PubMed - indexed for MEDLINE]

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