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    Results: 1 to 20 of 125

    1.

    Mithramycin downregulates proinflammatory cytokine-induced matrix metalloproteinase gene expression in articular chondrocytes.

    Liacini A, Sylvester J, Li WQ, Zafarullah M.

    Arthritis Res Ther. 2005;7(4):R777-83. Epub 2005 Apr 4.

    PMID:
    15987479
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    5.

    Induction of matrix metalloproteinase-13 gene expression by TNF-alpha is mediated by MAP kinases, AP-1, and NF-kappaB transcription factors in articular chondrocytes.

    Liacini A, Sylvester J, Li WQ, Huang W, Dehnade F, Ahmad M, Zafarullah M.

    Exp Cell Res. 2003 Aug 1;288(1):208-17.

    PMID:
    12878172
    [PubMed - indexed for MEDLINE]
    6.

    Triptolide suppresses proinflammatory cytokine-induced matrix metalloproteinase and aggrecanase-1 gene expression in chondrocytes.

    Liacini A, Sylvester J, Zafarullah M.

    Biochem Biophys Res Commun. 2005 Feb 4;327(1):320-7.

    PMID:
    15629465
    [PubMed - indexed for MEDLINE]
    7.

    Retinoic acid blocks pro-inflammatory cytokine-induced matrix metalloproteinase production by down-regulating JNK-AP-1 signaling in human chondrocytes.

    Ho LJ, Lin LC, Hung LF, Wang SJ, Lee CH, Chang DM, Lai JH, Tai TY.

    Biochem Pharmacol. 2005 Jul 15;70(2):200-8.

    PMID:
    15946654
    [PubMed - indexed for MEDLINE]
    8.

    Signaling pathways implicated in oncostatin M-induced aggrecanase-1 and matrix metalloproteinase-13 expression in human articular chondrocytes.

    El Mabrouk M, Sylvester J, Zafarullah M.

    Biochim Biophys Acta. 2007 Mar;1773(3):309-20. Epub 2006 Dec 15.

    PMID:
    17208315
    [PubMed - indexed for MEDLINE]
    9.

    Interleukin-4 antagonizes oncostatin M and transforming growth factor beta-induced responses in articular chondrocytes.

    El Mabrouk M, Qureshi HY, Li WQ, Sylvester J, Zafarullah M.

    J Cell Biochem. 2008 Feb 1;103(2):588-97.

    PMID:
    17546624
    [PubMed - indexed for MEDLINE]
    10.

    Role of interleukin 6 (IL-6)/IL-6R-induced signal tranducers and activators of transcription and mitogen-activated protein kinase/extracellular.

    Legendre F, Bogdanowicz P, Boumediene K, Pujol JP.

    J Rheumatol. 2005 Jul;32(7):1307-16.

    PMID:
    15996070
    [PubMed - indexed for MEDLINE]
    11.

    Novel p38 mitogen-activated protein kinase inhibitor R-130823 protects cartilage by down-regulating matrix metalloproteinase-1,-13 and prostaglandin E2 production in human chondrocytes.

    Wada Y, Shimada K, Sugimoto K, Kimura T, Ushiyama S.

    Int Immunopharmacol. 2006 Feb;6(2):144-55. Epub 2005 Aug 24.

    PMID:
    16399619
    [PubMed - indexed for MEDLINE]
    12.

    Phase 2 enzyme inducer sulphoraphane blocks matrix metalloproteinase production in articular chondrocytes.

    Kim HA, Yeo Y, Kim WU, Kim S.

    Rheumatology (Oxford). 2009 Aug;48(8):932-8. Epub 2009 Jun 2.

    PMID:
    19491303
    [PubMed - indexed for MEDLINE]
    Free Article
    13.

    TGF-beta-induced expression of tissue inhibitor of metalloproteinases-3 gene in chondrocytes is mediated by extracellular signal-regulated kinase pathway and Sp1 transcription factor.

    Qureshi HY, Sylvester J, El Mabrouk M, Zafarullah M.

    J Cell Physiol. 2005 May;203(2):345-52.

    PMID:
    15468069
    [PubMed - indexed for MEDLINE]
    14.

    The differential effects of IL-1 and TNF-alpha on proinflammatory cytokine and matrix metalloproteinase expression in human chondrosarcoma cells.

    Shi J, Schmitt-Talbot E, DiMattia DA, Dullea RG.

    Inflamm Res. 2004 Aug;53(8):377-89. Epub 2004 Aug 10.

    PMID:
    15316669
    [PubMed - indexed for MEDLINE]
    15.

    MyD88, IRAK1 and TRAF6 knockdown in human chondrocytes inhibits interleukin-1-induced matrix metalloproteinase-13 gene expression and promoter activity by impairing MAP kinase activation.

    Ahmad R, Sylvester J, Zafarullah M.

    Cell Signal. 2007 Dec;19(12):2549-57. Epub 2007 Aug 25.

    PMID:
    17905570
    [PubMed - indexed for MEDLINE]
    16.

    Involvement of H-Ras and reactive oxygen species in proinflammatory cytokine-induced matrix metalloproteinase-13 expression in human articular chondrocytes.

    Ahmad R, Sylvester J, Ahmad M, Zafarullah M.

    Arch Biochem Biophys. 2011 Mar 15;507(2):350-5. Epub 2011 Jan 3.

    PMID:
    21211511
    [PubMed - indexed for MEDLINE]
    17.

    Differential regulation of cytokine-induced MMP-1 and MMP-13 expression by p38 kinase inhibitors in human chondrosarcoma cells: potential role of Runx2 in mediating p38 effects.

    Pei Y, Harvey A, Yu XP, Chandrasekhar S, Thirunavukkarasu K.

    Osteoarthritis Cartilage. 2006 Aug;14(8):749-58. Epub 2006 Mar 20.

    PMID:
    16549373
    [PubMed - indexed for MEDLINE]
    18.

    Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption.

    Young DA, Lakey RL, Pennington CJ, Jones D, Kevorkian L, Edwards DR, Cawston TE, Clark IM.

    Arthritis Res Ther. 2005;7(3):R503-12. Epub 2005 Feb 22.

    PMID:
    15899037
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1beta in articular chondrocytes.

    Afif H, Benderdour M, Mfuna-Endam L, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H.

    Arthritis Res Ther. 2007;9(2):R31.

    PMID:
    17386086
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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