PubMed

Polymorphisms in the SLC2A2 (GLUT2) gene are associated with the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study.

Laukkanen O, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M; Finnish Diabetes Prevention Study.

Diabetes. 2005 Jul;54(7):2256-60.PMID: 15983230 [PubMed - indexed for MEDLINE]Related articlesFree article

Physical activity modifies the effect of SNPs in the SLC2A2 (GLUT2) and ABCC8 (SUR1) genes on the risk of developing type 2 diabetes.

Kilpeläinen TO, Lakka TA, Laaksonen DE, Laukkanen O, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M; Finnish Diabetes Prevention Study Group.

Physiol Genomics. 2007 Oct 22;31(2):264-72. Epub 2007 Jul 17. Erratum in: Physiol Genomics. 2008 Feb 19;32(3):419. PMID: 17636114 [PubMed - indexed for MEDLINE]Related articlesFree article

The G-250A promoter polymorphism of the hepatic lipase gene predicts the conversion from impaired glucose tolerance to type 2 diabetes mellitus: the Finnish Diabetes Prevention Study.

Todorova B, Kubaszek A, Pihlajamäki J, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M; Finnish Diabetes Prevention Study.

J Clin Endocrinol Metab. 2004 May;89(5):2019-23.PMID: 15126514 [PubMed - indexed for MEDLINE]Related articlesFree article

Promoter polymorphisms of the TNF-alpha (G-308A) and IL-6 (C-174G) genes predict the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study.

Kubaszek A, Pihlajamäki J, Komarovski V, Lindi V, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M; Finnish Diabetes Prevention Study.

Diabetes. 2003 Jul;52(7):1872-6.PMID: 12829659 [PubMed - indexed for MEDLINE]Related articlesFree article

Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes. The Finnish Diabetes Prevention Study.

Laukkanen O, Pihlajamäki J, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M; Finnish Diabetes Prevention Study Group.

Diabetologia. 2004 May;47(5):871-7. Epub 2004 May 1.PMID: 15127203 [PubMed - indexed for MEDLINE]Related articles

Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A and the Pro12Ala substitution of PPARG2 predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.

Andrulionyte L, Peltola P, Chiasson JL, Laakso M; STOP-NIDDM Study Group.

Diabetes. 2006 Jul;55(7):2148-52.PMID: 16804087 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of common genetic variation in the FOXO1 gene with beta-cell dysfunction, impaired glucose tolerance, and type 2 diabetes.

Müssig K, Staiger H, Machicao F, Stancáková A, Kuusisto J, Laakso M, Thamer C, Machann J, Schick F, Claussen CD, Stefan N, Fritsche A, Häring HU.

J Clin Endocrinol Metab. 2009 Apr;94(4):1353-60. Epub 2009 Jan 13.PMID: 19141580 [PubMed - indexed for MEDLINE]Related articles

Common polymorphisms of the PPAR-gamma2 (Pro12Ala) and PGC-1alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial.

Andrulionytè L, Zacharova J, Chiasson JL, Laakso M; STOP-NIDDM Study Group.

Diabetologia. 2004 Dec;47(12):2176-84. Epub 2004 Dec 8.PMID: 15592662 [PubMed - indexed for MEDLINE]Related articles

Association of the Leu72Met polymorphism of the ghrelin gene with the risk of Type 2 diabetes in subjects with impaired glucose tolerance in the Finnish Diabetes Prevention Study.

Mager U, Lindi V, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Pulkkinen L, Uusitupa M; Finnish Diabetes Prevention Study Group.

Diabet Med. 2006 Jun;23(6):685-9.PMID: 16759313 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in leptin receptor gene is associated with type 2 diabetes and body weight: The Finnish Diabetes Prevention Study.

Salopuro T, Pulkkinen L, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M; Finnish Diabetes Prevention Study Group.

Int J Obes (Lond). 2005 Oct;29(10):1245-51.PMID: 15997246 [PubMed - indexed for MEDLINE]Related articles

Association between a deletion/insertion polymorphism in the alpha2B-adrenergic receptor gene and insulin secretion and Type 2 diabetes. The Finnish Diabetes Prevention Study.

Siitonen N, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M.

Diabetologia. 2004 Aug;47(8):1416-24. Epub 2004 Jul 28.PMID: 15309292 [PubMed - indexed for MEDLINE]Related articles

Single nucleotide polymorphisms of the HNF4alpha gene are associated with the conversion to type 2 diabetes mellitus: the STOP-NIDDM trial.

Andrulionyte L, Laukkanen O, Chiasson JL, Laakso M; STOP-NIDDM Study Group.

J Mol Med. 2006 Aug;84(8):701-8. Epub 2006 Jul 13.PMID: 16838170 [PubMed - indexed for MEDLINE]Related articles

Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion.

Wang J, Kuusisto J, Vänttinen M, Kuulasmaa T, Lindström J, Tuomilehto J, Uusitupa M, Laakso M.

Diabetologia. 2007 Jun;50(6):1192-200. Epub 2007 Apr 17.PMID: 17437080 [PubMed - indexed for MEDLINE]Related articles

Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome: The Finnish Diabetes Prevention Study.

Kilpeläinen TO, Lakka TA, Laaksonen DE, Mager U, Salopuro T, Kubaszek A, Todorova B, Laukkanen O, Lindström J, Eriksson JG, Hämäläinen H, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M; Finnish Diabetes Prevention Study Group.

Metabolism. 2008 Mar;57(3):428-36.PMID: 18249219 [PubMed - indexed for MEDLINE]Related articles

The common polymorphisms (single nucleotide polymorphism [SNP] +45 and SNP +276) of the adiponectin gene predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.

Zacharova J, Chiasson JL, Laakso M; STOP-NIDDM Study Group.

Diabetes. 2005 Mar;54(3):893-9.PMID: 15734870 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish Diabetes Prevention Study.

Laukkanen O, Pihlajamäki J, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M; Finnish Diabetes Prevention Study Group.

J Clin Endocrinol Metab. 2004 Dec;89(12):6286-90.PMID: 15579791 [PubMed - indexed for MEDLINE]Related articlesFree article

Single nucleotide polymorphisms of the peroxisome proliferator-activated receptor-alpha gene (PPARA) influence the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.

Andrulionyte L, Kuulasmaa T, Chiasson JL, Laakso M; STOP-NIDDM Study Group.

Diabetes. 2007 Apr;56(4):1181-6. Epub 2007 Feb 22.PMID: 17317762 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study.

Lindi VI, Uusitupa MI, Lindström J, Louheranta A, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Laakso M, Tuomilehto J; Finnish Diabetes Prevention Study.

Diabetes. 2002 Aug;51(8):2581-6.PMID: 12145174 [PubMed - indexed for MEDLINE]Related articlesFree article

SNPs in PPARG associate with type 2 diabetes and interact with physical activity.

Kilpeläinen TO, Lakka TA, Laaksonen DE, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Lindi V, Tuomilehto J, Uusitupa M, Laakso M.

Med Sci Sports Exerc. 2008 Jan;40(1):25-33.PMID: 18091023 [PubMed - indexed for MEDLINE]Related articles

Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action.

Barroso I, Luan J, Middelberg RP, Harding AH, Franks PW, Jakes RW, Clayton D, Schafer AJ, O'Rahilly S, Wareham NJ.

PLoS Biol. 2003 Oct;1(1):E20. Epub 2003 Oct 13. Erratum in: PLoS Biol. 2003 Dec;1(3):445. PMID: 14551916 [PubMed - indexed for MEDLINE]Related articlesFree article