PubMed

Metformin prevents high-glucose-induced endothelial cell death through a mitochondrial permeability transition-dependent process.

Detaille D, Guigas B, Chauvin C, Batandier C, Fontaine E, Wiernsperger N, Leverve X.

Diabetes. 2005 Jul;54(7):2179-87.PMID: 15983220 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons.

El-Mir MY, Detaille D, R-Villanueva G, Delgado-Esteban M, Guigas B, Attia S, Fontaine E, Almeida A, Leverve X.

J Mol Neurosci. 2008;34(1):77-87. Epub 2007 Nov 27.PMID: 18040888 [PubMed - indexed for MEDLINE]Related articles

Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study.

Guigas B, Detaille D, Chauvin C, Batandier C, De Oliveira F, Fontaine E, Leverve X.

Biochem J. 2004 Sep 15;382(Pt 3):877-84.PMID: 15175014 [PubMed - indexed for MEDLINE]Related articlesFree article

Metformin prevents glucose-induced protein kinase C-beta2 activation in human umbilical vein endothelial cells through an antioxidant mechanism.

Gallo A, Ceolotto G, Pinton P, Iori E, Murphy E, Rutter GA, Rizzuto R, Semplicini A, Avogaro A.

Diabetes. 2005 Apr;54(4):1123-31.PMID: 15793252 [PubMed - indexed for MEDLINE]Related articlesFree article

Rotenone inhibits the mitochondrial permeability transition-induced cell death in U937 and KB cells.

Chauvin C, De Oliveira F, Ronot X, Mousseau M, Leverve X, Fontaine E.

J Biol Chem. 2001 Nov 2;276(44):41394-8. Epub 2001 Aug 29.PMID: 11527970 [PubMed - indexed for MEDLINE]Related articlesFree article

Metformin suppresses high glucose-induced poly(adenosine diphosphate-ribose) polymerase overactivation in aortic endothelial cells.

Mahrouf-Yorgov M, Marie N, Borderie D, Djelidi R, Bonnefont-Rousselot D, Legrand A, Beaudeux JL, Peynet J.

Metabolism. 2009 Apr;58(4):525-33.PMID: 19303974 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial Ca2+ uptake during simulated ischemia does not affect permeability transition pore opening upon simulated reperfusion.

Ruiz-Meana M, Garcia-Dorado D, Miró-Casas E, Abellán A, Soler-Soler J.

Cardiovasc Res. 2006 Sep 1;71(4):715-24. Epub 2006 Jun 21.PMID: 16860295 [PubMed - indexed for MEDLINE]Related articlesFree article

Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with anti-tumor 1,4-anthracenediones.

Wang Y, Perchellet EM, Ward MM, Lou K, Hua DH, Perchellet JP.

Anticancer Drugs. 2005 Oct;16(9):953-67.PMID: 16162972 [PubMed - indexed for MEDLINE]Related articles

Suppression of mitochondrial permeability transition pore and induction of lymphoma P388 cell death by cyclosporin A.

Teplova V, Evtodienko Y, Odinokova I, Kruglov A, Kudrjavtsev A.

IUBMB Life. 2000 Jul;50(1):75-80.PMID: 11087125 [PubMed - indexed for MEDLINE]Related articles

Evaluation of gliclazide ability to attenuate the hyperglycaemic 'memory' induced by high glucose in isolated human endothelial cells.

Corgnali M, Piconi L, Ihnat M, Ceriello A.

Diabetes Metab Res Rev. 2008 May-Jun;24(4):301-9.PMID: 18088078 [PubMed - indexed for MEDLINE]Related articles

Metformin prevents the impairment of endothelium-dependent vascular relaxation induced by high glucose challenge in rabbit isolated perfused kidneys.

Gomes MB, Cailleaux S, Tibiriçá E.

Naunyn Schmiedebergs Arch Pharmacol. 2005 Jul;372(1):24-30. Epub 2005 Aug 26.PMID: 16133490 [PubMed - indexed for MEDLINE]Related articles

Dual antiglioma action of metformin: cell cycle arrest and mitochondria-dependent apoptosis.

Isakovic A, Harhaji L, Stevanovic D, Markovic Z, Sumarac-Dumanovic M, Starcevic V, Micic D, Trajkovic V.

Cell Mol Life Sci. 2007 May;64(10):1290-302.PMID: 17447005 [PubMed - indexed for MEDLINE]Related articles

Coenzyme Q10 prevents high glucose-induced oxidative stress in human umbilical vein endothelial cells.

Tsuneki H, Sekizaki N, Suzuki T, Kobayashi S, Wada T, Okamoto T, Kimura I, Sasaoka T.

Eur J Pharmacol. 2007 Jul 2;566(1-3):1-10. Epub 2007 Mar 19.PMID: 17434478 [PubMed - indexed for MEDLINE]Related articles

Inhibition of NADPH oxidase-related oxidative stress-triggered signaling by honokiol suppresses high glucose-induced human endothelial cell apoptosis.

Sheu ML, Chiang CK, Tsai KS, Ho FM, Weng TI, Wu HY, Liu SH.

Free Radic Biol Med. 2008 Jun 15;44(12):2043-50. Epub 2008 Apr 3.PMID: 18423412 [PubMed - indexed for MEDLINE]Related articles

Oxidative stress and endothelium influenced by metformin in type 2 diabetes mellitus.

Skrha J, Prázný M, Hilgertová J, Kvasnicka J, Kalousová M, Zima T.

Eur J Clin Pharmacol. 2007 Dec;63(12):1107-14. Epub 2007 Sep 15.PMID: 17874238 [PubMed - indexed for MEDLINE]Related articles

Effect of transient and permanent permeability transition pore opening on NAD(P)H localization in intact cells.

Dumas JF, Argaud L, Cottet-Rousselle C, Vial G, Gonzalez C, Detaille D, Leverve X, Fontaine E.

J Biol Chem. 2009 May 29;284(22):15117-25. Epub 2009 Apr 3.PMID: 19346250 [PubMed - indexed for MEDLINE]Related articles

Melatonin prevents oxidative stress-mediated mitochondrial permeability transition and death in skeletal muscle cells.

Hibaoui Y, Roulet E, Ruegg UT.

J Pineal Res. 2009 Oct;47(3):238-52. Epub 2009 Aug 3.PMID: 19664004 [PubMed - in process]Related articles

Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase.

Davis BJ, Xie Z, Viollet B, Zou MH.

Diabetes. 2006 Feb;55(2):496-505.PMID: 16443786 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor-1 receptor activation prevents high glucose-induced mitochondrial dysfunction, cytochrome-c release and apoptosis.

Li Y, Wu H, Khardori R, Song YH, Lu YW, Geng YJ.

Biochem Biophys Res Commun. 2009 Jun 26;384(2):259-64. Epub 2009 May 4.PMID: 19406106 [PubMed - indexed for MEDLINE]Related articles

Constant and intermittent high glucose enhances endothelial cell apoptosis through mitochondrial superoxide overproduction.

Piconi L, Quagliaro L, Assaloni R, Da Ros R, Maier A, Zuodar G, Ceriello A.

Diabetes Metab Res Rev. 2006 May-Jun;22(3):198-203.PMID: 16453381 [PubMed - indexed for MEDLINE]Related articles