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    Results: 1 to 20 of 237

    1.

    Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation.

    Paulsson JF, Westermark GT.

    Diabetes. 2005 Jul;54(7):2117-25.PMID: 15983213 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death.

    Marzban L, Rhodes CJ, Steiner DF, Haataja L, Halban PA, Verchere CB.

    Diabetes. 2006 Aug;55(8):2192-201.PMID: 16873681 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide.

    Marzban L, Trigo-Gonzalez G, Zhu X, Rhodes CJ, Halban PA, Steiner DF, Verchere CB.

    Diabetes. 2004 Jan;53(1):141-8.PMID: 14693708 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site.

    Wang J, Xu J, Finnerty J, Furuta M, Steiner DF, Verchere CB.

    Diabetes. 2001 Mar;50(3):534-9.PMID: 11246872 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Role of carboxypeptidase E in processing of pro-islet amyloid polypeptide in {beta}-cells.

    Marzban L, Soukhatcheva G, Verchere CB.

    Endocrinology. 2005 Apr;146(4):1808-17. Epub 2004 Dec 23.PMID: 15618358 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Processing of pro-islet amyloid polypeptide (proIAPP) by the prohormone convertase PC2.

    Badman MK, Shennan KI, Jermany JL, Docherty K, Clark A.

    FEBS Lett. 1996 Jan 15;378(3):227-31.PMID: 8557106 [PubMed - indexed for MEDLINE]Related articles

    7.

    Processing of synthetic pro-islet amyloid polypeptide (proIAPP) 'amylin' by recombinant prohormone convertase enzymes, PC2 and PC3, in vitro.

    Higham CE, Hull RL, Lawrie L, Shennan KI, Morris JF, Birch NP, Docherty K, Clark A.

    Eur J Biochem. 2000 Aug;267(16):4998-5004.PMID: 10931181 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets.

    Paulsson JF, Andersson A, Westermark P, Westermark GT.

    Diabetologia. 2006 Jun;49(6):1237-46. Epub 2006 Mar 29.PMID: 16570161 [PubMed - indexed for MEDLINE]Related articles

    9.

    Processing of pro-islet amyloid polypeptide in the constitutive and regulated secretory pathways of beta cells.

    Marzban L, Trigo-Gonzalez G, Verchere CB.

    Mol Endocrinol. 2005 Aug;19(8):2154-63. Epub 2005 Mar 31.PMID: 15802374 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Pro islet amyloid polypeptide (ProIAPP) immunoreactivity in the islets of Langerhans.

    Westermark GT, Steiner DF, Gebre-Medhin S, Engström U, Westermark P.

    Ups J Med Sci. 2000;105(2):97-106.PMID: 11095107 [PubMed - indexed for MEDLINE]Related articles

    11.

    Amyloidogenicity of recombinant human pro-islet amyloid polypeptide (ProIAPP).

    Krampert M, Bernhagen J, Schmucker J, Horn A, Schmauder A, Brunner H, Voelter W, Kapurniotu A.

    Chem Biol. 2000 Nov;7(11):855-71.PMID: 11094339 [PubMed - indexed for MEDLINE]Related articles

    12.

    Characterization of the heparin binding site in the N-terminus of human pro-islet amyloid polypeptide: implications for amyloid formation.

    Abedini A, Tracz SM, Cho JH, Raleigh DP.

    Biochemistry. 2006 Aug 1;45(30):9228-37.PMID: 16866369 [PubMed - indexed for MEDLINE]Related articles

    13.

    Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide.

    Rouillé Y, Martin S, Steiner DF.

    J Biol Chem. 1995 Nov 3;270(44):26488-96.PMID: 7592866 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor.

    Ugleholdt R, Poulsen ML, Holst PJ, Irminger JC, Orskov C, Pedersen J, Rosenkilde MM, Zhu X, Steiner DF, Holst JJ.

    J Biol Chem. 2006 Apr 21;281(16):11050-7. Epub 2006 Feb 13.PMID: 16476726 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Amyloid formation by pro-islet amyloid polypeptide processing intermediates: examination of the role of protein heparan sulfate interactions and implications for islet amyloid formation in type 2 diabetes.

    Meng F, Abedini A, Song B, Raleigh DP.

    Biochemistry. 2007 Oct 30;46(43):12091-9. Epub 2007 Oct 9.PMID: 17924651 [PubMed - indexed for MEDLINE]Related articles

    16.

    Chromogranin A processing and secretion: specific role of endogenous and exogenous prohormone convertases in the regulated secretory pathway.

    Eskeland NL, Zhou A, Dinh TQ, Wu H, Parmer RJ, Mains RE, O'Connor DT.

    J Clin Invest. 1996 Jul 1;98(1):148-56.PMID: 8690787 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Molecular physiology of the islet amyloid polypeptide (IAPP)/amylin gene in man, rat, and transgenic mice.

    Höppener JW, Oosterwijk C, van Hulst KL, Verbeek JS, Capel PJ, de Koning EJ, Clark A, Jansz HS, Lips CJ.

    J Cell Biochem. 1994;55 Suppl:39-53. Review.PMID: 7929617 [PubMed - indexed for MEDLINE]Related articles

    18.

    Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology.

    Jaikaran ET, Clark A.

    Biochim Biophys Acta. 2001 Nov 29;1537(3):179-203. Review.PMID: 11731221 [PubMed - indexed for MEDLINE]Related articles

    19.

    The role of prohormone convertases PC1 (PC3) and PC2 in the cell-specific processing of proglucagon.

    Mineo I, Matsumura T, Shingu R, Namba M, Kuwajima M, Matsuzawa Y.

    Biochem Biophys Res Commun. 1995 Feb 15;207(2):646-51.PMID: 7864855 [PubMed - indexed for MEDLINE]Related articles

    20.

    Structural elements that direct specific processing of different mammalian subtilisin-like prohormone convertases.

    Zhou A, Paquet L, Mains RE.

    J Biol Chem. 1995 Sep 15;270(37):21509-16.PMID: 7665562 [PubMed - indexed for MEDLINE]Related articlesFree article

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