PubMed

Saturated and cis/trans unsaturated acyl CoA esters differentially regulate wild-type and polymorphic beta-cell ATP-sensitive K+ channels.

Riedel MJ, Light PE.

Diabetes. 2005 Jul;54(7):2070-9.PMID: 15983208 [PubMed - indexed for MEDLINE]Related articlesFree article

Kir6.2 polymorphisms sensitize beta-cell ATP-sensitive potassium channels to activation by acyl CoAs: a possible cellular mechanism for increased susceptibility to type 2 diabetes?

Riedel MJ, Boora P, Steckley D, de Vries G, Light PE.

Diabetes. 2003 Oct;52(10):2630-5.PMID: 14514649 [PubMed - indexed for MEDLINE]Related articlesFree article

Acyl coenzyme A esters differentially activate cardiac and beta-cell adenosine triphosphate-sensitive potassium channels in a side-chain length-specific manner.

Fox JE, Magga J, Giles WR, Light PE.

Metabolism. 2003 Oct;52(10):1313-9.PMID: 14564684 [PubMed - indexed for MEDLINE]Related articles

Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif.

Bränström R, Leibiger IB, Leibiger B, Klement G, Nilsson J, Arhem P, Aspinwall CA, Corkey BE, Larsson O, Berggren PO.

Diabetologia. 2007 Aug;50(8):1670-7. Epub 2007 May 24.PMID: 17522836 [PubMed - indexed for MEDLINE]Related articles

Elevation in intracellular long-chain acyl-coenzyme A esters lead to reduced beta-cell excitability via activation of adenosine 5'-triphosphate-sensitive potassium channels.

Webster NJ, Searle GJ, Lam PP, Huang YC, Riedel MJ, Harb G, Gaisano HY, Holt A, Light PE.

Endocrinology. 2008 Jul;149(7):3679-87. Epub 2008 Mar 27.PMID: 18372336 [PubMed - indexed for MEDLINE]Related articlesFree article

Long chain coenzyme A esters activate the pore-forming subunit (Kir6. 2) of the ATP-regulated potassium channel.

Bränström R, Leibiger IB, Leibiger B, Corkey BE, Berggren PO, Larsson O.

J Biol Chem. 1998 Nov 20;273(47):31395-400.PMID: 9813050 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes.

Bränström R, Aspinwall CA, Välimäki S, Ostensson CG, Tibell A, Eckhard M, Brandhorst H, Corkey BE, Berggren PO, Larsson O.

Diabetologia. 2004 Feb;47(2):277-83. Epub 2004 Jan 23.PMID: 14740158 [PubMed - indexed for MEDLINE]Related articles

Adenosine triphosphate-sensitive potassium (K(ATP)) channel activity is coupled with insulin resistance in obesity and type 2 diabetes mellitus.

Wasada T.

Intern Med. 2002 Feb;41(2):84-90. Review.PMID: 11868613 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for a unique long chain acyl-CoA ester binding site on the ATP-regulated potassium channel in mouse pancreatic beta cells.

Bränström R, Corkey BE, Berggren PO, Larsson O.

J Biol Chem. 1997 Jul 11;272(28):17390-4.PMID: 9211879 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic regulation of the pancreatic beta-cell ATP-sensitive K+ channel: a pas de deux.

Tarasov A, Dusonchet J, Ashcroft F.

Diabetes. 2004 Dec;53 Suppl 3:S113-22. Review.PMID: 15561898 [PubMed - indexed for MEDLINE]Related articlesFree article

Membrane phosphoinositides control insulin secretion through their effects on ATP-sensitive K+ channel activity.

Lin CW, Yan F, Shimamura S, Barg S, Shyng SL.

Diabetes. 2005 Oct;54(10):2852-8.PMID: 16186385 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA.

Gribble FM, Proks P, Corkey BE, Ashcroft FM.

J Biol Chem. 1998 Oct 9;273(41):26383-7.PMID: 9756869 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of adenosine triphosphate-sensitive potassium channels by acyl coenzyme A esters involves multiple phosphatidylinositol 4,5-bisphosphate-interacting residues.

Manning Fox JE, Nichols CG, Light PE.

Mol Endocrinol. 2004 Mar;18(3):679-86. Epub 2003 Dec 23.PMID: 14694085 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-chain acyl-coenzyme A esters and fatty acids directly link metabolism to K(ATP) channels in the heart.

Liu GX, Hanley PJ, Ray J, Daut J.

Circ Res. 2001 May 11;88(9):918-24.PMID: 11349001 [PubMed - indexed for MEDLINE]Related articlesFree article

Iptakalim, a vascular ATP-sensitive potassium (KATP) channel opener, closes rat pancreatic beta-cell KATP channels and increases insulin release.

Misaki N, Mao X, Lin YF, Suga S, Li GH, Liu Q, Chang Y, Wang H, Wakui M, Wu J.

J Pharmacol Exp Ther. 2007 Aug;322(2):871-8. Epub 2007 May 23.PMID: 17522344 [PubMed - indexed for MEDLINE]Related articlesFree article

A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults.

Tarasov AI, Nicolson TJ, Riveline JP, Taneja TK, Baldwin SA, Baldwin JM, Charpentier G, Gautier JF, Froguel P, Vaxillaire M, Rutter GA.

Diabetes. 2008 Jun;57(6):1595-604. Epub 2008 Mar 17.PMID: 18346985 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel KCNJ11 mutation associated with congenital hyperinsulinism reduces the intrinsic open probability of beta-cell ATP-sensitive potassium channels.

Lin YW, MacMullen C, Ganguly A, Stanley CA, Shyng SL.

J Biol Chem. 2006 Feb 3;281(5):3006-12. Epub 2005 Dec 6.PMID: 16332676 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of the ATP-sensitive K+ channel by long chain acyl-CoA. A role in modulation of pancreatic beta-cell glucose sensitivity.

Larsson O, Deeney JT, Bränström R, Berggren PO, Corkey BE.

J Biol Chem. 1996 May 3;271(18):10623-6.PMID: 8631866 [PubMed - indexed for MEDLINE]Related articlesFree article

Specificity of activation by phosphoinositides determines lipid regulation of Kir channels.

Rohács T, Lopes CM, Jin T, Ramdya PP, Molnár Z, Logothetis DE.

Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):745-50. Epub 2003 Jan 13.PMID: 12525701 [PubMed - indexed for MEDLINE]Related articlesFree article

Long chain CoA esters as competitive antagonists of phosphatidylinositol 4,5-bisphosphate activation in Kir channels.

Rapedius M, Soom M, Shumilina E, Schulze D, Schönherr R, Kirsch C, Lang F, Tucker SJ, Baukrowitz T.

J Biol Chem. 2005 Sep 2;280(35):30760-7. Epub 2005 Jun 24.PMID: 15980413 [PubMed - indexed for MEDLINE]Related articlesFree article