PubMed

Identification of naturally processed HLA-A2--restricted proinsulin epitopes by reverse immunology.

Hassainya Y, Garcia-Pons F, Kratzer R, Lindo V, Greer F, Lemonnier FA, Niedermann G, van Endert PM.

Diabetes. 2005 Jul;54(7):2053-9.PMID: 15983206 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA class I epitope discovery in type 1 diabetes.

van Endert P, Hassainya Y, Lindo V, Bach JM, Blancou P, Lemonnier F, Mallone R.

Ann N Y Acad Sci. 2006 Oct;1079:190-7.PMID: 17130554 [PubMed - indexed for MEDLINE]Related articles

Recognition of human proinsulin leader sequence by class I-restricted T-cells in HLA-A*0201 transgenic mice and in human type 1 diabetes.

Toma A, Laïka T, Haddouk S, Luce S, Briand JP, Camoin L, Connan F, Lambert M, Caillat-Zucman S, Carel JC, Muller S, Choppin J, Lemonnier F, Boitard C.

Diabetes. 2009 Feb;58(2):394-402. Epub 2008 Nov 14.PMID: 19011169 [PubMed - indexed for MEDLINE]Related articlesFree article

T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin.

Congia M, Patel S, Cope AP, De Virgiliis S, Sønderstrup G.

Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3833-8.PMID: 9520453 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA class I epitope discovery in type 1 diabetes: independent and reproducible identification of proinsulin epitopes of CD8 T cells--report of the IDS T Cell Workshop Committee.

Pinkse GG, Boitard C, Tree TI, Peakman M, Roep BO.

Ann N Y Acad Sci. 2006 Oct;1079:19-23.PMID: 17130527 [PubMed - indexed for MEDLINE]Related articles

Equivalent specificity of peripheral blood and islet-infiltrating CD8+ T lymphocytes in spontaneously diabetic HLA-A2 transgenic NOD mice.

Enée E, Martinuzzi E, Blancou P, Bach JM, Mallone R, van Endert P.

J Immunol. 2008 Apr 15;180(8):5430-8.PMID: 18390725 [PubMed - indexed for MEDLINE]Related articlesFree article

Experimental autoimmune insulitis. Induction by T lymphocytes specific for a peptide of proinsulin.

Griffin AC, Zhao W, Wegmann KW, Hickley WF.

Am J Pathol. 1995 Sep;147(3):845-57.PMID: 7545875 [PubMed - indexed for MEDLINE]Related articlesFree article

Promiscuous binding of proinsulin peptides to Type 1 diabetes-permissive and -protective HLA class II molecules.

Astill TP, Ellis RJ, Arif S, Tree TI, Peakman M.

Diabetologia. 2003 Apr;46(4):496-503. Epub 2003 Apr 9.PMID: 12684749 [PubMed - indexed for MEDLINE]Related articles

Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401.

Wicker LS, Chen SL, Nepom GT, Elliott JF, Freed DC, Bansal A, Zheng S, Herman A, Lernmark A, Zaller DM, Peterson LB, Rothbard JB, Cummings R, Whiteley PJ.

J Clin Invest. 1996 Dec 1;98(11):2597-603.PMID: 8958223 [PubMed - indexed for MEDLINE]Related articlesFree article

Naturally processed and presented epitopes of the islet cell autoantigen IA-2 eluted from HLA-DR4.

Peakman M, Stevens EJ, Lohmann T, Narendran P, Dromey J, Alexander A, Tomlinson AJ, Trucco M, Gorga JC, Chicz RM.

J Clin Invest. 1999 Nov;104(10):1449-57.PMID: 10562307 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes.

Chen W, Bergerot I, Elliott JF, Harrison LC, Abiru N, Eisenbarth GS, Delovitch TL.

J Immunol. 2001 Nov 1;167(9):4926-35.PMID: 11673498 [PubMed - indexed for MEDLINE]Related articlesFree article

CD8 and cytotoxic T cells in type 1 diabetes.

Peakman M.

Novartis Found Symp. 2008;292:113-9; discussion 119-29, 202-3.PMID: 19203096 [PubMed - indexed for MEDLINE]Related articles

A peptide-binding motif for I-A(g7), the class II major histocompatibility complex (MHC) molecule of NOD and Biozzi AB/H mice.

Harrison LC, Honeyman MC, Trembleau S, Gregori S, Gallazzi F, Augstein P, Brusic V, Hammer J, Adorini L.

J Exp Med. 1997 Mar 17;185(6):1013-21.PMID: 9091575 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA-DR binding analysis of peptides from islet antigens in IDDM.

Geluk A, van Meijgaarden KE, Schloot NC, Drijfhout JW, Ottenhoff TH, Roep BO.

Diabetes. 1998 Oct;47(10):1594-601.PMID: 9753297 [PubMed - indexed for MEDLINE]Related articlesFree article

"Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes.

Serreze DV, Marron MP, Dilorenzo TP.

Ann N Y Acad Sci. 2007 Apr;1103:103-11. Epub 2007 Mar 21.PMID: 17376821 [PubMed - indexed for MEDLINE]Related articles

Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes.

Ouyang Q, Standifer NE, Qin H, Gottlieb P, Verchere CB, Nepom GT, Tan R, Panagiotopoulos C.

Diabetes. 2006 Nov;55(11):3068-74.PMID: 17065344 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a new HLA-A2-restricted T-cell epitope within HM1.24 as immunotherapy target for multiple myeloma.

Hundemer M, Schmidt S, Condomines M, Lupu A, Hose D, Moos M, Cremer F, Kleist C, Terness P, Belle S, Ho AD, Goldschmidt H, Klein B, Christensen O.

Exp Hematol. 2006 Apr;34(4):486-96.PMID: 16569595 [PubMed - indexed for MEDLINE]Related articlesFree article

Is there MHC Class II restriction of the response to MHC Class I in transplant patients?

Papassavas AC, Barnardo MC, Bunce M, Welsh KI.

Transplantation. 2002 Feb 27;73(4):642-51.PMID: 11889447 [PubMed - indexed for MEDLINE]Related articles

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice.

Nakayama M, Abiru N, Moriyama H, Babaya N, Liu E, Miao D, Yu L, Wegmann DR, Hutton JC, Elliott JF, Eisenbarth GS.

Nature. 2005 May 12;435(7039):220-3.PMID: 15889095 [PubMed - indexed for MEDLINE]Related articlesFree article

T cell recognition of human pre-proinsulin peptides depends on the polymorphism at HLA DQ locus: a study using HLA DQ8 and DQ6 transgenic mice.

Raju R, Munn SR, David CS.

Hum Immunol. 1997 Nov;58(1):21-9.PMID: 9438206 [PubMed - indexed for MEDLINE]Related articles