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    Results: 1 to 20 of 195

    1.

    Dual role of phosphofructokinase-2/fructose bisphosphatase-2 in regulating the compartmentation and expression of glucokinase in hepatocytes.

    Payne VA, Arden C, Wu C, Lange AJ, Agius L.

    Diabetes. 2005 Jul;54(7):1949-57.PMID: 15983194 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Contributions of glucokinase and phosphofructokinase-2/fructose bisphosphatase-2 to the elevated glycolysis in hepatocytes from Zucker fa/fa rats.

    Payne VA, Arden C, Lange AJ, Agius L.

    Am J Physiol Regul Integr Comp Physiol. 2007 Aug;293(2):R618-25. Epub 2007 Jun 6.PMID: 17553851 [PubMed - indexed for MEDLINE]Related articles

    3.

    Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

    Mukhtar MH, Payne VA, Arden C, Harbottle A, Khan S, Lange AJ, Agius L.

    Am J Physiol Regul Integr Comp Physiol. 2008 Mar;294(3):R766-74. Epub 2008 Jan 16.PMID: 18199594 [PubMed - indexed for MEDLINE]Related articles

    4.

    A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells.

    Arden C, Hampson LJ, Huang GC, Shaw JA, Aldibbiat A, Holliman G, Manas D, Khan S, Lange AJ, Agius L.

    Biochem J. 2008 Apr 1;411(1):41-51.PMID: 18039179 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Glucokinase regulatory protein is associated with mitochondria in hepatocytes.

    Arden C, Baltrusch S, Agius L.

    FEBS Lett. 2006 Apr 3;580(8):2065-70. Epub 2006 Mar 10.PMID: 16542652 [PubMed - indexed for MEDLINE]Related articles

    6.

    The physiological role of glucokinase binding and translocation in hepatocytes.

    Agius L.

    Adv Enzyme Regul. 1998;38:303-31.PMID: 9762360 [PubMed - indexed for MEDLINE]Related articles

    7.

    The role of the regulatory protein of glucokinase in the glucose sensory mechanism of the hepatocyte.

    de la Iglesia N, Mukhtar M, Seoane J, Guinovart JJ, Agius L.

    J Biol Chem. 2000 Apr 7;275(14):10597-603.PMID: 10744755 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Regulation of hepatic glucose metabolism by translocation of glucokinase between the nucleus and the cytoplasm in hepatocytes.

    Toyoda Y, Tsuchida A, Iwami E, Shironoguchi H, Miwa I.

    Horm Metab Res. 2001 Jun;33(6):329-36.PMID: 11456280 [PubMed - indexed for MEDLINE]Related articles

    9.

    Interaction of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) with glucokinase activates glucose phosphorylation and glucose metabolism in insulin-producing cells.

    Massa L, Baltrusch S, Okar DA, Lange AJ, Lenzen S, Tiedge M.

    Diabetes. 2004 Apr;53(4):1020-9.PMID: 15047617 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Adenovirus-mediated overexpression of liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in gluconeogenic rat hepatoma cells. Paradoxical effect on Fru-2,6-P2 levels.

    Argaud D, Lange AJ, Becker TC, Okar DA, el-Maghrabi MR, Newgard CB, Pilkis SJ.

    J Biol Chem. 1995 Oct 13;270(41):24229-36.PMID: 7592629 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    A potential role for fructose-2,6-bisphosphate in the stimulation of hepatic glucokinase gene expression.

    Wu C, Okar DA, Stoeckman AK, Peng LJ, Herrera AH, Herrera JE, Towle HC, Lange AJ.

    Endocrinology. 2004 Feb;145(2):650-8. Epub 2003 Nov 14.PMID: 14617577 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Glucose-6-phosphatase overexpression lowers glucose 6-phosphate and inhibits glycogen synthesis and glycolysis in hepatocytes without affecting glucokinase translocation. Evidence against feedback inhibition of glucokinase.

    Aiston S, Trinh KY, Lange AJ, Newgard CB, Agius L.

    J Biol Chem. 1999 Aug 27;274(35):24559-66.PMID: 10455119 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and metformin inhibit hepatic glucose phosphorylation by an AMP-activated protein kinase-independent effect on glucokinase translocation.

    Guigas B, Bertrand L, Taleux N, Foretz M, Wiernsperger N, Vertommen D, Andreelli F, Viollet B, Hue L.

    Diabetes. 2006 Apr;55(4):865-74.PMID: 16567505 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Regulation of hepatic 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase gene expression by glucagon.

    Rosa JL, Ventura F, Tauler A, Bartrons R.

    J Biol Chem. 1993 Oct 25;268(30):22540-5.PMID: 8226764 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Fundamental metabolic differences between hepatocytes and islet beta-cells revealed by glucokinase overexpression.

    Berman HK, Newgard CB.

    Biochemistry. 1998 Mar 31;37(13):4543-52.PMID: 9521775 [PubMed - indexed for MEDLINE]Related articles

    16.

    Stimulation of glucose-6-phosphatase gene expression by glucose and fructose-2,6-bisphosphate.

    Argaud D, Kirby TL, Newgard CB, Lange AJ.

    J Biol Chem. 1997 May 9;272(19):12854-61.PMID: 9139747 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Molecular coordination of hepatic glucose metabolism by the 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase:glucokinase complex.

    Smith WE, Langer S, Wu C, Baltrusch S, Okar DA.

    Mol Endocrinol. 2007 Jun;21(6):1478-87. Epub 2007 Mar 20.PMID: 17374851 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Characterization of glucokinase-binding protein epitopes by a phage-displayed peptide library. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel interaction partner.

    Baltrusch S, Lenzen S, Okar DA, Lange AJ, Tiedge M.

    J Biol Chem. 2001 Nov 23;276(47):43915-23. Epub 2001 Aug 24.PMID: 11522786 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Overexpression of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase in mouse liver lowers blood glucose by suppressing hepatic glucose production.

    Wu C, Okar DA, Newgard CB, Lange AJ.

    J Clin Invest. 2001 Jan;107(1):91-8.PMID: 11134184 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation.

    Farrelly D, Brown KS, Tieman A, Ren J, Lira SA, Hagan D, Gregg R, Mookhtiar KA, Hariharan N.

    Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14511-6.PMID: 10588736 [PubMed - indexed for MEDLINE]Related articlesFree article

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