PubMed

Activation of the SPHK/S1P signalling pathway is coupled to muscarinic receptor-dependent regulation of peripheral airways.

Pfaff M, Powaga N, Akinci S, Schütz W, Banno Y, Wiegand S, Kummer W, Wess J, Haberberger RV.

Respir Res. 2005 May 31;6:48.PMID: 15927078 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells.

Tauseef M, Kini V, Knezevic N, Brannan M, Ramchandaran R, Fyrst H, Saba J, Vogel SM, Malik AB, Mehta D.

Circ Res. 2008 Nov 7;103(10):1164-72. Epub 2008 Oct 10.PMID: 18849324 [PubMed - indexed for MEDLINE]Related articlesFree article

Anti-inflammatory effects of sphingosine kinase modulation in inflammatory arthritis.

Lai WQ, Irwan AW, Goh HH, Howe HS, Yu DT, Valle-Oñate R, McInnes IB, Melendez AJ, Leung BP.

J Immunol. 2008 Dec 1;181(11):8010-7.PMID: 19017993 [PubMed - indexed for MEDLINE]Related articlesFree article

Signaling pathways involved in sphingosine kinase activation and sphingosine-1-phosphate release in rat myometrium in late pregnancy: role in the induction of cyclooxygenase 2.

Serrano-Sanchez M, Tanfin Z, Leiber D.

Endocrinology. 2008 Sep;149(9):4669-79.PMID: 18723875 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of muscarinic receptor subtypes in the constriction of peripheral airways: studies on receptor-deficient mice.

Struckmann N, Schwering S, Wiegand S, Gschnell A, Yamada M, Kummer W, Wess J, Haberberger RV.

Mol Pharmacol. 2003 Dec;64(6):1444-51.PMID: 14645675 [PubMed - indexed for MEDLINE]Related articlesFree article

K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling.

Hong JH, Youm JK, Kwon MJ, Park BD, Lee YM, Lee SI, Shin DM, Lee SH.

J Invest Dermatol. 2008 Sep;128(9):2166-78. Epub 2008 Apr 3.PMID: 18385762 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential regulation of sphingosine kinases 1 and 2 in lung injury.

Wadgaonkar R, Patel V, Grinkina N, Romano C, Liu J, Zhao Y, Sammani S, Garcia JG, Natarajan V.

Am J Physiol Lung Cell Mol Physiol. 2009 Apr;296(4):L603-13. Epub 2009 Jan 23.PMID: 19168577 [PubMed - indexed for MEDLINE]Related articles

Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts.

Bu S, Yamanaka M, Pei H, Bielawska A, Bielawski J, Hannun YA, Obeid L, Trojanowska M.

FASEB J. 2006 Jan;20(1):184-6. Epub 2005 Nov 8.PMID: 16278291 [PubMed - indexed for MEDLINE]Related articlesFree article

Exogenous sphingosine 1-phosphate and sphingosine kinase activated by endothelin-1 induced myometrial contraction through differential mechanisms.

Leiber D, Banno Y, Tanfin Z.

Am J Physiol Cell Physiol. 2007 Jan;292(1):C240-50. Epub 2006 Sep 6.PMID: 16956968 [PubMed - indexed for MEDLINE]Related articlesFree article

Deletion of the sphingosine kinase-1 gene influences cell fate during hypoxia and glucose deprivation in adult mouse cardiomyocytes.

Tao R, Zhang J, Vessey DA, Honbo N, Karliner JS.

Cardiovasc Res. 2007 Apr 1;74(1):56-63. Epub 2007 Jan 23.PMID: 17320845 [PubMed - indexed for MEDLINE]Related articlesFree article

Low dose N, N-dimethylsphingosine is cardioprotective and activates cytosolic sphingosine kinase by a PKCepsilon dependent mechanism.

Jin ZQ, Karliner JS.

Cardiovasc Res. 2006 Sep 1;71(4):725-34. Epub 2006 Jun 12.PMID: 16831409 [PubMed - indexed for MEDLINE]Related articlesFree article

Sphingosine kinase activity is required for sphingosine-mediated phospholipase D activation in C2C12 myoblasts.

Meacci E, Cencetti F, Donati C, Nuti F, Becciolini L, Bruni P.

Biochem J. 2004 Aug 1;381(Pt 3):655-63.PMID: 15109308 [PubMed - indexed for MEDLINE]Related articlesFree article

Signalling mechanisms in sphingosine 1-phosphate-promoted mesangial cell proliferation.

Katsuma S, Hada Y, Ueda T, Shiojima S, Hirasawa A, Tanoue A, Takagaki K, Ohgi T, Yano J, Tsujimoto G.

Genes Cells. 2002 Dec;7(12):1217-30.PMID: 12485162 [PubMed - indexed for MEDLINE]Related articles

Sphingosine kinase signalling in immune cells: potential as novel therapeutic targets.

Melendez AJ.

Biochim Biophys Acta. 2008 Jan;1784(1):66-75. Epub 2007 Aug 14. Review.PMID: 17913601 [PubMed - indexed for MEDLINE]Related articles

Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-beta-stimulated collagen production by cardiac fibroblasts.

Gellings Lowe N, Swaney JS, Moreno KM, Sabbadini RA.

Cardiovasc Res. 2009 May 1;82(2):303-12. Epub 2009 Feb 19.PMID: 19228708 [PubMed - indexed for MEDLINE]Related articles

Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a "come-and-get-me" signal.

Gude DR, Alvarez SE, Paugh SW, Mitra P, Yu J, Griffiths R, Barbour SE, Milstien S, Spiegel S.

FASEB J. 2008 Aug;22(8):2629-38. Epub 2008 Mar 24.PMID: 18362204 [PubMed - indexed for MEDLINE]Related articlesFree article

Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors.

Meyer zu Heringdorf D, Lass H, Alemany R, Laser KT, Neumann E, Zhang C, Schmidt M, Rauen U, Jakobs KH, van Koppen CJ.

EMBO J. 1998 May 15;17(10):2830-7.PMID: 9582276 [PubMed - indexed for MEDLINE]Related articlesFree article

Sphingosine-1-phosphate/sphingosine kinase pathway is involved in mouse airway hyperresponsiveness.

Roviezzo F, Di Lorenzo A, Bucci M, Brancaleone V, Vellecco V, De Nardo M, Orlotti D, De Palma R, Rossi F, D'Agostino B, Cirino G.

Am J Respir Cell Mol Biol. 2007 Jun;36(6):757-62. Epub 2007 Feb 22.PMID: 17322125 [PubMed - indexed for MEDLINE]Related articlesFree article

[SphK-1/S1P signal pathway in CML cells]

Huang WR, Wang LS, Wang H, Duan HF, Li QF, Gao CJ, DA WM.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2008 Aug;16(4):730-3. Chinese. PMID: 18718048 [PubMed - indexed for MEDLINE]Related articles

Inducible nitric oxide has protective effect on fumonisin B1 hepatotoxicity in mice via modulation of sphingosine kinase.

Suzuki H, Riley RT, Sharma RP.

Toxicology. 2007 Jan 5;229(1-2):42-53. Epub 2006 Sep 29.PMID: 17095132 [PubMed - indexed for MEDLINE]Related articlesFree article