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    Results: 1 to 20 of 636

    1.

    Reduction of hepatic and adipose tissue glucocorticoid receptor expression with antisense oligonucleotides improves hyperglycemia and hyperlipidemia in diabetic rodents without causing systemic glucocorticoid antagonism.

    Watts LM, Manchem VP, Leedom TA, Rivard AL, McKay RA, Bao D, Neroladakis T, Monia BP, Bodenmiller DM, Cao JX, Zhang HY, Cox AL, Jacobs SJ, Michael MD, Sloop KW, Bhanot S.

    Diabetes. 2005 Jun;54(6):1846-53.PMID: 15919808 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Antisense oligonucleotides targeted against glucocorticoid receptor reduce hepatic glucose production and ameliorate hyperglycemia in diabetic mice.

    Liang Y, Osborne MC, Monia BP, Bhanot S, Watts LM, She P, DeCarlo SO, Chen X, Demarest K.

    Metabolism. 2005 Jul;54(7):848-55.PMID: 15988691 [PubMed - indexed for MEDLINE]Related articles

    3.

    Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice.

    Yu XX, Murray SF, Pandey SK, Booten SL, Bao D, Song XZ, Kelly S, Chen S, McKay R, Monia BP, Bhanot S.

    Hepatology. 2005 Aug;42(2):362-71.PMID: 16001399 [PubMed - indexed for MEDLINE]Related articles

    4.

    Reduced adiposity and improved insulin sensitivity in obese mice with antisense suppression of 4E-BP2 expression.

    Yu XX, Pandey SK, Booten SL, Murray SF, Monia BP, Bhanot S.

    Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E530-9. Epub 2008 Jan 15.PMID: 18198353 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Antihyperglycemic action of angiotensin II receptor antagonist, valsartan, in streptozotocin-induced diabetic rats.

    Chan P, Wong KL, Liu IM, Tzeng TF, Yang TL, Cheng JT.

    J Hypertens. 2003 Apr;21(4):761-9.PMID: 12658023 [PubMed - indexed for MEDLINE]Related articles

    6.

    Reduction of hepatosteatosis and lipid levels by an adipose differentiation-related protein antisense oligonucleotide.

    Imai Y, Varela GM, Jackson MB, Graham MJ, Crooke RM, Ahima RS.

    Gastroenterology. 2007 May;132(5):1947-54. Epub 2007 Feb 23.PMID: 17484887 [PubMed - indexed for MEDLINE]Related articles

    7.

    SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats.

    Erion DM, Yonemitsu S, Nie Y, Nagai Y, Gillum MP, Hsiao JJ, Iwasaki T, Stark R, Weismann D, Yu XX, Murray SF, Bhanot S, Monia BP, Horvath TL, Gao Q, Samuel VT, Shulman GI.

    Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11288-93. Epub 2009 Jun 22.PMID: 19549853 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Differential responses of the growth hormone axis in two rat models of streptozotocin-induced insulinopenic diabetes.

    Kim E, Sohn S, Lee M, Jung J, Kineman RD, Park S.

    J Endocrinol. 2006 Feb;188(2):263-70.PMID: 16461552 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Expression analysis of hypothalamic and pituitary components of the growth hormone axis in fasted and streptozotocin-treated neuropeptide Y (NPY)-intact (NPY+/+) and NPY-knockout (NPY-/-) mice.

    Park S, Peng XD, Frohman LA, Kineman RD.

    Neuroendocrinology. 2005;81(6):360-71. Epub 2005 Oct 18.PMID: 16244497 [PubMed - indexed for MEDLINE]Related articles

    10.

    Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism.

    Koliwad SK, Kuo T, Shipp LE, Gray NE, Backhed F, So AY, Farese RV Jr, Wang JC.

    J Biol Chem. 2009 Sep 18;284(38):25593-601. Epub 2009 Jul 23.PMID: 19628874 [PubMed - indexed for MEDLINE]Related articles

    11.

    Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in mice.

    Liu Y, Nakagawa Y, Wang Y, Liu L, Du H, Wang W, Ren X, Lutfy K, Friedman TC.

    J Mol Endocrinol. 2008 Aug;41(2):53-64. Epub 2008 Jun 4.PMID: 18524870 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Mechanism for blockade of angiotensin subtype 1 receptors to lower plasma glucose in streptozotocin-induced diabetic rats.

    Chan P, Liu IM, Tzeng TF, Yang TL, Cheng JT.

    Diabetes Obes Metab. 2007 Jan;9(1):39-49.PMID: 17199717 [PubMed - indexed for MEDLINE]Related articles

    13.

    Improvement of insulin sensitivity after peroxisome proliferator-activated receptor-alpha agonist treatment is accompanied by paradoxical increase of circulating resistin levels.

    Haluzik MM, Lacinova Z, Dolinkova M, Haluzikova D, Housa D, Horinek A, Vernerova Z, Kumstyrova T, Haluzik M.

    Endocrinology. 2006 Sep;147(9):4517-24. Epub 2006 Jun 1.PMID: 16740970 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Dual specificity MAPK phosphatase 3 activates PEPCK gene transcription and increases gluconeogenesis in rat hepatoma cells.

    Xu H, Yang Q, Shen M, Huang X, Dembski M, Gimeno R, Tartaglia LA, Kapeller R, Wu Z.

    J Biol Chem. 2005 Oct 28;280(43):36013-8. Epub 2005 Aug 26.PMID: 16126724 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Reduction in glucagon receptor expression by an antisense oligonucleotide ameliorates diabetic syndrome in db/db mice.

    Liang Y, Osborne MC, Monia BP, Bhanot S, Gaarde WA, Reed C, She P, Jetton TL, Demarest KT.

    Diabetes. 2004 Feb;53(2):410-7.PMID: 14747292 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.

    Yamaguchi K, Yang L, McCall S, Huang J, Yu XX, Pandey SK, Bhanot S, Monia BP, Li YX, Diehl AM.

    Hepatology. 2007 Jun;45(6):1366-74.PMID: 17476695 [PubMed - indexed for MEDLINE]Related articles

    17.

    The messenger RNA profiles in liver, hypothalamus, white adipose tissue, and skeletal muscle of female Zucker diabetic fatty rats after topiramate treatment.

    Liang Y, She P, Wang X, Demarest K.

    Metabolism. 2006 Oct;55(10):1411-9.PMID: 16979414 [PubMed - indexed for MEDLINE]Related articles

    18.

    Inactivation of the glucocorticoid receptor in hepatocytes leads to fasting hypoglycemia and ameliorates hyperglycemia in streptozotocin-induced diabetes mellitus.

    Opherk C, Tronche F, Kellendonk C, Kohlmüller D, Schulze A, Schmid W, Schütz G.

    Mol Endocrinol. 2004 Jun;18(6):1346-53. Epub 2004 Mar 18.PMID: 15031319 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Role of glucocorticoids in the physiopathology of excessive fat deposition and insulin resistance.

    Asensio C, Muzzin P, Rohner-Jeanrenaud F.

    Int J Obes Relat Metab Disord. 2004 Dec;28 Suppl 4:S45-52. Review.PMID: 15592486 [PubMed - indexed for MEDLINE]Related articles

    20.

    Specific reduction of hepatic glucose 6-phosphate transporter-1 ameliorates diabetes while avoiding complications of glycogen storage disease.

    Sloop KW, Showalter AD, Cox AL, Cao JX, Siesky AM, Zhang HY, Irizarry AR, Murray SF, Booten SL, Finger EA, McKay RA, Monia BP, Bhanot S, Michael MD.

    J Biol Chem. 2007 Jun 29;282(26):19113-21. Epub 2007 May 3.PMID: 17478431 [PubMed - indexed for MEDLINE]Related articlesFree article

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