PubMed

Beta-cell secretory products activate alpha-cell ATP-dependent potassium channels to inhibit glucagon release.

Franklin I, Gromada J, Gjinovci A, Theander S, Wollheim CB.

Diabetes. 2005 Jun;54(6):1808-15.PMID: 15919803 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin regulates islet alpha-cell function by reducing KATP channel sensitivity to adenosine 5'-triphosphate inhibition.

Leung YM, Ahmed I, Sheu L, Gao X, Hara M, Tsushima RG, Diamant NE, Gaisano HY.

Endocrinology. 2006 May;147(5):2155-62. Epub 2006 Feb 2.PMID: 16455778 [PubMed - indexed for MEDLINE]Related articlesFree article

ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells.

Gromada J, Ma X, Høy M, Bokvist K, Salehi A, Berggren PO, Rorsman P.

Diabetes. 2004 Dec;53 Suppl 3:S181-9.PMID: 15561909 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose stimulates glucagon release in single rat alpha-cells by mechanisms that mirror the stimulus-secretion coupling in beta-cells.

Olsen HL, Theander S, Bokvist K, Buschard K, Wollheim CB, Gromada J.

Endocrinology. 2005 Nov;146(11):4861-70. Epub 2005 Aug 4.PMID: 16081632 [PubMed - indexed for MEDLINE]Related articlesFree article

A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.

MacDonald PE, De Marinis YZ, Ramracheya R, Salehi A, Ma X, Johnson PR, Cox R, Eliasson L, Rorsman P.

PLoS Biol. 2007 Jun;5(6):e143.PMID: 17503968 [PubMed - indexed for MEDLINE]Related articlesFree article

Imidazoline NNC77-0074 stimulates insulin secretion and inhibits glucagon release by control of Ca(2+)-dependent exocytosis in pancreatic alpha- and beta-cells.

Høy M, Olsen HL, Andersen HS, Bokvist K, Buschard K, Hansen J, Jacobsen P, Petersen JS, Rorsman P, Gromada J.

Eur J Pharmacol. 2003 Apr 11;466(1-2):213-21.PMID: 12679159 [PubMed - indexed for MEDLINE]Related articles

Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells.

Ishihara H, Maechler P, Gjinovci A, Herrera PL, Wollheim CB.

Nat Cell Biol. 2003 Apr;5(4):330-5.PMID: 12640462 [PubMed - indexed for MEDLINE]Related articles

Regulation of glucagon secretion at low glucose concentrations: evidence for adenosine triphosphate-sensitive potassium channel involvement.

Muñoz A, Hu M, Hussain K, Bryan J, Aguilar-Bryan L, Rajan AS.

Endocrinology. 2005 Dec;146(12):5514-21. Epub 2005 Aug 25.PMID: 16123162 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose triggers protein kinase A-dependent insulin secretion in mouse pancreatic islets through activation of the K+ATP channel-dependent pathway.

Thams P, Anwar MR, Capito K.

Eur J Endocrinol. 2005 Apr;152(4):671-7.PMID: 15817925 [PubMed - indexed for MEDLINE]Related articlesFree article

New insights concerning the glucose-dependent insulin secretagogue action of glucagon-like peptide-1 in pancreatic beta-cells.

Holz GG.

Horm Metab Res. 2004 Nov-Dec;36(11-12):787-94. Erratum in: Horm Metab Res. 2005 Feb;37(2):126. Holz, G [corrected to Holz, GG]. PMID: 15655710 [PubMed - indexed for MEDLINE]Related articles

ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.

Chapman JC, McClenaghan NH, Cosgrove KE, Hashmi MN, Shepherd RM, Giesberts AN, White SJ, Ammälä C, Flatt PR, Dunne MJ.

Diabetes. 1999 Dec;48(12):2349-57.PMID: 10580423 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of glucagon release in mouse -cells by KATP channels and inactivation of TTX-sensitive Na+ channels.

Göpel SO, Kanno T, Barg S, Weng XG, Gromada J, Rorsman P.

J Physiol. 2000 Nov 1;528(Pt 3):509-20.PMID: 11060128 [PubMed - indexed for MEDLINE]Related articlesFree article

BPDZ 154 activates adenosine 5'-triphosphate-sensitive potassium channels: in vitro studies using rodent insulin-secreting cells and islets isolated from patients with hyperinsulinism.

Cosgrove KE, Antoine MH, Lee AT, Barnes PD, de Tullio P, Clayton P, McCloy R, De Lonlay P, Nihoul-Fékété C, Robert JJ, Saudubray JM, Rahier J, Lindley KJ, Hussain K, Aynsley-Green A, Pirotte B, Lebrun P, Dunne MJ.

J Clin Endocrinol Metab. 2002 Nov;87(11):4860-8.PMID: 12414839 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose activates both K(ATP) channel-dependent and K(ATP) channel-independent signaling pathways in human islets.

Straub SG, James RF, Dunne MJ, Sharp GW.

Diabetes. 1998 May;47(5):758-63.PMID: 9588447 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic alpha-cells.

Ravier MA, Rutter GA.

Diabetes. 2005 Jun;54(6):1789-97.PMID: 15919801 [PubMed - indexed for MEDLINE]Related articlesFree article

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion.

Hohmeier HE, Mulder H, Chen G, Henkel-Rieger R, Prentki M, Newgard CB.

Diabetes. 2000 Mar;49(3):424-30.PMID: 10868964 [PubMed - indexed for MEDLINE]Related articlesFree article

Peptidergic regulation of maturation of the stimulus-secretion coupling in fetal islet beta cells.

Sjöholm A, Sandberg E, Ostenson CG, Efendić S.

Pancreas. 2000 Apr;20(3):282-9.PMID: 10766455 [PubMed - indexed for MEDLINE]Related articles

Inhibition of glucagon secretion.

Young A.

Adv Pharmacol. 2005;52:151-71. Review.PMID: 16492545 [PubMed - indexed for MEDLINE]Related articles

Induction of beta-cell rest by a Kir6.2/SUR1-selective K(ATP)-channel opener preserves beta-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose.

Ritzel RA, Hansen JB, Veldhuis JD, Butler PC.

J Clin Endocrinol Metab. 2004 Feb;89(2):795-805.PMID: 14764798 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for two different types of P2 receptors stimulating insulin secretion from pancreatic B cell.

Petit P, Hillaire-Buys D, Manteghetti M, Debrus S, Chapal J, Loubatières-Mariani MM.

Br J Pharmacol. 1998 Nov;125(6):1368-74.PMID: 9863669 [PubMed - indexed for MEDLINE]Related articlesFree article