PubMed

Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release.

Ravier MA, Güldenagel M, Charollais A, Gjinovci A, Caille D, Söhl G, Wollheim CB, Willecke K, Henquin JC, Meda P.

Diabetes. 2005 Jun;54(6):1798-807.PMID: 15919802 [PubMed - indexed for MEDLINE]Related articlesFree article

Cx36-mediated coupling reduces beta-cell heterogeneity, confines the stimulating glucose concentration range, and affects insulin release kinetics.

Speier S, Gjinovci A, Charollais A, Meda P, Rupnik M.

Diabetes. 2007 Apr;56(4):1078-86.PMID: 17395748 [PubMed - indexed for MEDLINE]Related articlesFree article

Connexin 36 controls synchronization of Ca2+ oscillations and insulin secretion in MIN6 cells.

Calabrese A, Zhang M, Serre-Beinier V, Caton D, Mas C, Satin LS, Meda P.

Diabetes. 2003 Feb;52(2):417-24.PMID: 12540616 [PubMed - indexed for MEDLINE]Related articlesFree article

Junctional communication of pancreatic beta cells contributes to the control of insulin secretion and glucose tolerance.

Charollais A, Gjinovci A, Huarte J, Bauquis J, Nadal A, Martín F, Andreu E, Sánchez-Andrés JV, Calabrese A, Bosco D, Soria B, Wollheim CB, Herrera PL, Meda P.

J Clin Invest. 2000 Jul;106(2):235-43.PMID: 10903339 [PubMed - indexed for MEDLINE]Related articlesFree article

Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression.

Serre-Beinier V, Bosco D, Zulianello L, Charollais A, Caille D, Charpantier E, Gauthier BR, Diaferia GR, Giepmans BN, Lupi R, Marchetti P, Deng S, Buhler L, Berney T, Cirulli V, Meda P.

Hum Mol Genet. 2009 Feb 1;18(3):428-39. Epub 2008 Nov 10.PMID: 19000992 [PubMed - indexed for MEDLINE]Related articles

Beta cells preferentially exchange cationic molecules via connexin 36 gap junction channels.

Charpantier E, Cancela J, Meda P.

Diabetologia. 2007 Nov;50(11):2332-41. Epub 2007 Sep 8.PMID: 17828386 [PubMed - indexed for MEDLINE]Related articles

Cx36 involvement in insulin secretion: characteristics and mechanism.

Meda P.

Cell Commun Adhes. 2003 Jul-Dec;10(4-6):431-5.PMID: 14681053 [PubMed - indexed for MEDLINE]Related articles

Connexin-36 contributes to control function of insulin-producing cells.

Le Gurun S, Martin D, Formenton A, Maechler P, Caille D, Waeber G, Meda P, Haefliger JA.

J Biol Chem. 2003 Sep 26;278(39):37690-7. Epub 2003 May 22.PMID: 12766175 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of alpha 1 connexin does not alter the prenatal differentiation of pancreatic beta cells and leads to the identification of another islet cell connexin.

Charollais A, Serre V, Mock C, Cogne F, Bosco D, Meda P.

Dev Genet. 1999;24(1-2):13-26.PMID: 10079507 [PubMed - indexed for MEDLINE]Related articles

Cx36 and the function of endocrine pancreas.

Calabrese A, Güldenagel M, Charollais A, Mas C, Caton D, Bauquis J, Serre-Beinier V, Caille D, Söhl G, Teubner B, Le Gurun S, Trovato-Salinaro A, Condorelli DF, Haefliger JA, Willecke K, Meda P.

Cell Commun Adhes. 2001;8(4-6):387-91.PMID: 12064624 [PubMed - indexed for MEDLINE]Related articles

Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels.

Szollosi A, Nenquin M, Aguilar-Bryan L, Bryan J, Henquin JC.

J Biol Chem. 2007 Jan 19;282(3):1747-56. Epub 2006 Nov 30.PMID: 17138557 [PubMed - indexed for MEDLINE]Related articlesFree article

Differentiating the effects of Cx36 and E-cadherin for proper insulin secretion of MIN6 cells.

Calabrese A, Caton D, Meda P.

Exp Cell Res. 2004 Apr 1;294(2):379-91.PMID: 15023528 [PubMed - indexed for MEDLINE]Related articles

A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells.

Wellershaus K, Degen J, Deuchars J, Theis M, Charollais A, Caille D, Gauthier B, Janssen-Bienhold U, Sonntag S, Herrera P, Meda P, Willecke K.

Exp Cell Res. 2008 Mar 10;314(5):997-1012. Epub 2008 Jan 12.PMID: 18258229 [PubMed - indexed for MEDLINE]Related articles

Disorganization of cytoplasmic Ca(2+) oscillations and pulsatile insulin secretion in islets from ob/ obmice.

Ravier MA, Sehlin J, Henquin JC.

Diabetologia. 2002 Aug;45(8):1154-63. Epub 2002 Jul 4.PMID: 12189446 [PubMed - indexed for MEDLINE]Related articles

Overnight culture unmasks glucose-induced insulin secretion in mouse islets lacking ATP-sensitive K+ channels by improving the triggering Ca2+ signal.

Szollosi A, Nenquin M, Henquin JC.

J Biol Chem. 2007 May 18;282(20):14768-76. Epub 2007 Mar 27.PMID: 17389589 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytoplasmic Ca2+ oscillations in pancreatic beta-cells.

Hellman B, Gylfe E, Grapengiesser E, Lund PE, Berts A.

Biochim Biophys Acta. 1992 Dec 11;1113(3-4):295-305. Review.PMID: 1450203 [PubMed - indexed for MEDLINE]Related articles

The oscillatory behavior of pancreatic islets from mice with mitochondrial glycerol-3-phosphate dehydrogenase knockout.

Ravier MA, Eto K, Jonkers FC, Nenquin M, Kadowaki T, Henquin JC.

J Biol Chem. 2000 Jan 21;275(3):1587-93.PMID: 10636849 [PubMed - indexed for MEDLINE]Related articlesFree article

Synchronization of Ca(2+)-signals within insulin-secreting pseudoislets: effects of gap-junctional uncouplers.

Squires PE, Hauge-Evans AC, Persaud SJ, Jones PM.

Cell Calcium. 2000 May;27(5):287-96.PMID: 10859595 [PubMed - indexed for MEDLINE]Related articles

Hepatocyte nuclear factor-4alpha is essential for glucose-stimulated insulin secretion by pancreatic beta-cells.

Miura A, Yamagata K, Kakei M, Hatakeyama H, Takahashi N, Fukui K, Nammo T, Yoneda K, Inoue Y, Sladek FM, Magnuson MA, Kasai H, Miyagawa J, Gonzalez FJ, Shimomura I.

J Biol Chem. 2006 Feb 24;281(8):5246-57. Epub 2005 Dec 23.PMID: 16377800 [PubMed - indexed for MEDLINE]Related articlesFree article

ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells.

Allagnat F, Alonso F, Martin D, Abderrahmani A, Waeber G, Haefliger JA.

J Biol Chem. 2008 Feb 29;283(9):5226-34. Epub 2007 Dec 11.PMID: 18073214 [PubMed - indexed for MEDLINE]Related articlesFree article