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    Results: 1 to 20 of 186

    1.

    Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects.

    Karlsson HK, Zierath JR, Kane S, Krook A, Lienhard GE, Wallberg-Henriksson H.

    Diabetes. 2005 Jun;54(6):1692-7.PMID: 15919790 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Increased phosphorylation of Akt substrate of 160 kDa (AS160) in rat skeletal muscle in response to insulin or contractile activity.

    Bruss MD, Arias EB, Lienhard GE, Cartee GD.

    Diabetes. 2005 Jan;54(1):41-50.PMID: 15616009 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes.

    Kim YB, Nikoulina SE, Ciaraldi TP, Henry RR, Kahn BB.

    J Clin Invest. 1999 Sep;104(6):733-41.PMID: 10491408 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: a time-course and dose-response study.

    Sriwijitkamol A, Coletta DK, Wajcberg E, Balbontin GB, Reyna SM, Barrientes J, Eagan PA, Jenkinson CP, Cersosimo E, DeFronzo RA, Sakamoto K, Musi N.

    Diabetes. 2007 Mar;56(3):836-48.PMID: 17327455 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells.

    Bouzakri K, Ribaux P, Tomas A, Parnaud G, Rickenbach K, Halban PA.

    Diabetes. 2008 May;57(5):1195-204. Epub 2008 Feb 14.PMID: 18276765 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Effects of endurance exercise training on insulin signaling in human skeletal muscle: interactions at the level of phosphatidylinositol 3-kinase, Akt, and AS160.

    Frøsig C, Rose AJ, Treebak JT, Kiens B, Richter EA, Wojtaszewski JF.

    Diabetes. 2007 Aug;56(8):2093-102. Epub 2007 May 18.PMID: 17513702 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport.

    Cartee GD, Wojtaszewski JF.

    Appl Physiol Nutr Metab. 2007 Jun;32(3):557-66. Review.PMID: 17510697 [PubMed - indexed for MEDLINE]Related articles

    8.

    Impaired insulin-stimulated phosphorylation of Akt and AS160 in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment.

    Højlund K, Glintborg D, Andersen NR, Birk JB, Treebak JT, Frøsig C, Beck-Nielsen H, Wojtaszewski JF.

    Diabetes. 2008 Feb;57(2):357-66. Epub 2007 Oct 31.PMID: 17977950 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle.

    Taylor EB, An D, Kramer HF, Yu H, Fujii NL, Roeckl KS, Bowles N, Hirshman MF, Xie J, Feener EP, Goodyear LJ.

    J Biol Chem. 2008 Apr 11;283(15):9787-96. Epub 2008 Feb 13.PMID: 18276596 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Prior exercise increases phosphorylation of Akt substrate of 160 kDa (AS160) in rat skeletal muscle.

    Arias EB, Kim J, Funai K, Cartee GD.

    Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1191-200. Epub 2006 Dec 19.PMID: 17179389 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Increased AS160 phosphorylation, but not TBC1D1 phosphorylation, with increased postexercise insulin sensitivity in rat skeletal muscle.

    Funai K, Schweitzer GG, Sharma N, Kanzaki M, Cartee GD.

    Am J Physiol Endocrinol Metab. 2009 Jul;297(1):E242-51. Epub 2009 May 12.PMID: 19435856 [PubMed - indexed for MEDLINE]Related articles

    12.

    Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected].

    Storgaard H, Song XM, Jensen CB, Madsbad S, Björnholm M, Vaag A, Zierath JR.

    Diabetes. 2001 Dec;50(12):2770-8. Erratum in: Diabetes 2002 Feb;51(2):552. PMID: 11723060 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Contraction-stimulated glucose transport in rat skeletal muscle is sustained despite reversal of increased PAS-phosphorylation of AS160 and TBC1D1.

    Funai K, Cartee GD.

    J Appl Physiol. 2008 Dec;105(6):1788-95. Epub 2008 Sep 25.PMID: 18818383 [PubMed - indexed for MEDLINE]Related articles

    14.

    Globular adiponectin stimulates glucose transport in type 2 diabetic muscle.

    Kuoppamaa H, Skrobuk P, Sihvo M, Hiukka A, Chibalin AV, Zierath JR, Koistinen HA.

    Diabetes Metab Res Rev. 2008 Oct;24(7):554-62.PMID: 18615850 [PubMed - indexed for MEDLINE]Related articles

    15.

    The effect of exercise and insulin on AS160 phosphorylation and 14-3-3 binding capacity in human skeletal muscle.

    Howlett KF, Mathews A, Garnham A, Sakamoto K.

    Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E401-7. Epub 2007 Nov 27.PMID: 18042670 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes.

    Storgaard H, Jensen CB, Björnholm M, Song XM, Madsbad S, Zierath JR, Vaag AA.

    J Clin Endocrinol Metab. 2004 Mar;89(3):1301-11.PMID: 15001626 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study.

    Karlsson HK, Hällsten K, Björnholm M, Tsuchida H, Chibalin AV, Virtanen KA, Heinonen OJ, Lönnqvist F, Nuutila P, Zierath JR.

    Diabetes. 2005 May;54(5):1459-67.PMID: 15855334 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Inhibition of contraction-stimulated AMP-activated protein kinase inhibits contraction-stimulated increases in PAS-TBC1D1 and glucose transport without altering PAS-AS160 in rat skeletal muscle.

    Funai K, Cartee GD.

    Diabetes. 2009 May;58(5):1096-104. Epub 2009 Feb 10.PMID: 19208911 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Evidence against a role for insulin-signaling proteins PI 3-kinase and Akt in insulin resistance in human skeletal muscle induced by short-term GH infusion.

    Jessen N, Djurhuus CB, Jørgensen JO, Jensen LS, Møller N, Lund S, Schmitz O.

    Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E194-9. Epub 2004 Aug 31.PMID: 15339744 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    AS160 regulates insulin- and contraction-stimulated glucose uptake in mouse skeletal muscle.

    Kramer HF, Witczak CA, Taylor EB, Fujii N, Hirshman MF, Goodyear LJ.

    J Biol Chem. 2006 Oct 20;281(42):31478-85. Epub 2006 Aug 25.PMID: 16935857 [PubMed - indexed for MEDLINE]Related articlesFree article

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