PubMed

Pulsatile insulin secretion dictates systemic insulin delivery by regulating hepatic insulin extraction in humans.

Meier JJ, Veldhuis JD, Butler PC.

Diabetes. 2005 Jun;54(6):1649-56.PMID: 15919785 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide 1 increases mass but not frequency or orderliness of pulsatile insulin secretion.

Pørksen N, Grøfte B, Nyholm B, Holst JJ, Pincus SM, Veldhuis JD, Schmitz O, Butler PC.

Diabetes. 1998 Jan;47(1):45-9.PMID: 9421373 [PubMed - indexed for MEDLINE]Related articles

Direct measurement of pulsatile insulin secretion from the portal vein in human subjects.

Song SH, McIntyre SS, Shah H, Veldhuis JD, Hayes PC, Butler PC.

J Clin Endocrinol Metab. 2000 Dec;85(12):4491-9.PMID: 11134098 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic glucose production is regulated both by direct hepatic and extrahepatic effects of insulin in humans.

Lewis GF, Zinman B, Groenewoud Y, Vranic M, Giacca A.

Diabetes. 1996 Apr;45(4):454-62.PMID: 8603767 [PubMed - indexed for MEDLINE]Related articles

Acute and short-term administration of a sulfonylurea (gliclazide) increases pulsatile insulin secretion in type 2 diabetes.

Juhl CB, Pørksen N, Pincus SM, Hansen AP, Veldhuis JD, Schmitz O.

Diabetes. 2001 Aug;50(8):1778-84.PMID: 11473038 [PubMed - indexed for MEDLINE]Related articlesFree article

Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and beta-cell mass to age-related insulin resistance in rats.

Matveyenko AV, Veldhuis JD, Butler PC.

Am J Physiol Endocrinol Metab. 2008 Oct;295(4):E832-41. Epub 2008 Jul 29.PMID: 18664594 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide 1 increases secretory burst mass of pulsatile insulin secretion in patients with type 2 diabetes and impaired glucose tolerance.

Ritzel R, Schulte M, Pørksen N, Nauck MS, Holst JJ, Juhl C, März W, Schmitz O, Schmiegel WH, Nauck MA.

Diabetes. 2001 Apr;50(4):776-84.PMID: 11289042 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative study of insulin secretion and clearance in normal and obese subjects.

Polonsky KS, Given BD, Hirsch L, Shapiro ET, Tillil H, Beebe C, Galloway JA, Frank BH, Karrison T, Van Cauter E.

J Clin Invest. 1988 Feb;81(2):435-41.PMID: 3276729 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct assessment of splanchnic uptake and metabolic effects of human and porcine insulin.

Saccà L, Orofino G, Petrone A, Vigorito C.

J Clin Endocrinol Metab. 1984 Aug;59(2):191-6.PMID: 6145721 [PubMed - indexed for MEDLINE]Related articles

Effects of somatostatin on pulsatile insulin secretion: elective inhibition of insulin burst mass.

Pørksen N, Munn SR, Steers JL, Veldhuis JD, Butler PC.

Am J Physiol. 1996 Jun;270(6 Pt 1):E1043-9.PMID: 8764190 [PubMed - indexed for MEDLINE]Related articles

Decrease in beta-cell mass leads to impaired pulsatile insulin secretion, reduced postprandial hepatic insulin clearance, and relative hyperglucagonemia in the minipig.

Kjems LL, Kirby BM, Welsh EM, Veldhuis JD, Straume M, McIntyre SS, Yang D, Lefèbvre P, Butler PC.

Diabetes. 2001 Sep;50(9):2001-12.PMID: 11522665 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of sulfonylurea's stimulation of insulin secretion in vivo: selective amplification of insulin secretory burst mass.

Pørksen NK, Munn SR, Steers JL, Schmitz O, Veldhuis JD, Butler PC.

Diabetes. 1996 Dec;45(12):1792-7.PMID: 8922367 [PubMed - indexed for MEDLINE]Related articles

Differential effects of glucose stimulation upon rapid pulses and ultradian oscillations of insulin secretion.

Sturis J, O'Meara NM, Shapiro ET, Blackman JD, Tillil H, Polonsky KS, Van Cauter E.

J Clin Endocrinol Metab. 1993 Apr;76(4):895-901.PMID: 8473402 [PubMed - indexed for MEDLINE]Related articles

Human insulin release processes measured by intraportal sampling.

Pørksen N, Grøfte T, Greisen J, Mengel A, Juhl C, Veldhuis JD, Schmitz O, Rössle M, Vilstrup H.

Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E695-702.PMID: 11832375 [PubMed - indexed for MEDLINE]Related articlesFree article

Oscillations in insulin secretion during constant glucose infusion in normal man: relationship to changes in plasma glucose.

Shapiro ET, Tillil H, Polonsky KS, Fang VS, Rubenstein AH, Van Cauter E.

J Clin Endocrinol Metab. 1988 Aug;67(2):307-14.PMID: 3292558 [PubMed - indexed for MEDLINE]Related articles

C-peptide and insulin secretion. Relationship between peripheral concentrations of C-peptide and insulin and their secretion rates in the dog.

Polonsky KS, Pugh W, Jaspan JB, Cohen DM, Karrison T, Tager HS, Rubenstein AH.

J Clin Invest. 1984 Nov;74(5):1821-9.PMID: 6389599 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated basal insulin secretion and normal dynamic insulin sensitivity in borderline hypertension.

Piccardo MG, Turchetti G, Rosa MS, Pacini G.

Nutr Metab Cardiovasc Dis. 1999 Oct;9(5):244-9.PMID: 10656171 [PubMed - indexed for MEDLINE]Related articles

Effects of glucose ingestion versus infusion on pulsatile insulin secretion. The incretin effect is achieved by amplification of insulin secretory burst mass.

Pørksen N, Munn S, Steers J, Veldhuis JD, Butler PC.

Diabetes. 1996 Oct;45(10):1317-23.PMID: 8826965 [PubMed - indexed for MEDLINE]Related articles

Beta-cell activity and hepatic insulin extraction following dexamethasone administration in healthy subjects.

Kautzky-Willer A, Thomaseth K, Clodi M, Ludvik B, Waldhäusl W, Prager R, Pacini G.

Metabolism. 1996 Apr;45(4):486-91.PMID: 8609836 [PubMed - indexed for MEDLINE]Related articles

Intrahepatic transplanted islets in humans secrete insulin in a coordinate pulsatile manner directly into the liver.

Meier JJ, Hong-McAtee I, Galasso R, Veldhuis JD, Moran A, Hering BJ, Butler PC.

Diabetes. 2006 Aug;55(8):2324-32.PMID: 16873697 [PubMed - indexed for MEDLINE]Related articlesFree article