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    Results: 1 to 20 of 1179

    1.

    Dose-response effect of elevated plasma free fatty acid on insulin signaling.

    Belfort R, Mandarino L, Kashyap S, Wirfel K, Pratipanawatr T, Berria R, Defronzo RA, Cusi K.

    Diabetes. 2005 Jun;54(6):1640-8.PMID: 15919784 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients.

    Miyazaki Y, He H, Mandarino LJ, DeFronzo RA.

    Diabetes. 2003 Aug;52(8):1943-50.PMID: 12882909 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Discordant effects of a chronic physiological increase in plasma FFA on insulin signaling in healthy subjects with or without a family history of type 2 diabetes.

    Kashyap SR, Belfort R, Berria R, Suraamornkul S, Pratipranawatr T, Finlayson J, Barrentine A, Bajaj M, Mandarino L, DeFronzo R, Cusi K.

    Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E537-46. Epub 2004 May 4.PMID: 15126243 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes.

    Kashyap S, Belfort R, Gastaldelli A, Pratipanawatr T, Berria R, Pratipanawatr W, Bajaj M, Mandarino L, DeFronzo R, Cusi K.

    Diabetes. 2003 Oct;52(10):2461-74.PMID: 14514628 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Thiazolidinedione treatment prevents free fatty acid-induced insulin resistance in male wistar rats.

    Hevener AL, Reichart D, Janez A, Olefsky J.

    Diabetes. 2001 Oct;50(10):2316-22.PMID: 11574414 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Fatty acid-induced insulin resistance: decreased muscle PI3K activation but unchanged Akt phosphorylation.

    Kruszynska YT, Worrall DS, Ofrecio J, Frias JP, Macaraeg G, Olefsky JM.

    J Clin Endocrinol Metab. 2002 Jan;87(1):226-34.PMID: 11788651 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes.

    Storgaard H, Jensen CB, Björnholm M, Song XM, Madsbad S, Zierath JR, Vaag AA.

    J Clin Endocrinol Metab. 2004 Mar;89(3):1301-11.PMID: 15001626 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Sustained reduction in plasma free fatty acid concentration improves insulin action without altering plasma adipocytokine levels in subjects with strong family history of type 2 diabetes.

    Bajaj M, Suraamornkul S, Kashyap S, Cusi K, Mandarino L, DeFronzo RA.

    J Clin Endocrinol Metab. 2004 Sep;89(9):4649-55.PMID: 15356076 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade.

    Griffin ME, Marcucci MJ, Cline GW, Bell K, Barucci N, Lee D, Goodyear LJ, Kraegen EW, White MF, Shulman GI.

    Diabetes. 1999 Jun;48(6):1270-4.PMID: 10342815 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Does free fatty acid infusion impair insulin action also through an increase in oxidative stress?

    Paolisso G, Gambardella A, Tagliamonte MR, Saccomanno F, Salvatore T, Gualdiero P, D'Onofrio MV, Howard BV.

    J Clin Endocrinol Metab. 1996 Dec;81(12):4244-8.PMID: 8954022 [PubMed - indexed for MEDLINE]Related articles

    11.

    Plasma free fatty acids decrease insulin-stimulated skeletal muscle glucose uptake by suppressing glycolysis in conscious rats.

    Kim JK, Wi JK, Youn JH.

    Diabetes. 1996 Apr;45(4):446-53.PMID: 8603766 [PubMed - indexed for MEDLINE]Related articles

    12.

    Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty Acyl-CoAs and insulin action in type 2 diabetic patients.

    Bajaj M, Suraamornkul S, Romanelli A, Cline GW, Mandarino LJ, Shulman GI, DeFronzo RA.

    Diabetes. 2005 Nov;54(11):3148-53.PMID: 16249438 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Dose-response effects of free fatty acids on glucose and lipid metabolism during somatostatin blockade of growth hormone and insulin in humans.

    Gormsen LC, Jessen N, Gjedsted J, Gjedde S, Nørrelund H, Lund S, Christiansen JS, Nielsen S, Schmitz O, Møller N.

    J Clin Endocrinol Metab. 2007 May;92(5):1834-42. Epub 2007 Mar 6.PMID: 17341555 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Effect of obesity on susceptibility to fatty acid-induced peripheral tissue insulin resistance.

    Kruszynska YT, Olefsky JM, Frias JP.

    Metabolism. 2003 Feb;52(2):233-8.PMID: 12601639 [PubMed - indexed for MEDLINE]Related articles

    15.

    Relationship between insulin-mediated glucose disposal and lipid metabolism in man.

    Lillioja S, Bogardus C, Mott DM, Kennedy AL, Knowler WC, Howard BV.

    J Clin Invest. 1985 Apr;75(4):1106-15.PMID: 3886702 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Effect of pancreas transplantation on free fatty acid metabolism in uremic IDDM patients.

    Luzi L, Groop LC, Perseghin G, Taskinen MR, Hilden H, Bianchi E, Terruzzi I, Dodesini AR, Di Carlo V, Pozza G.

    Diabetes. 1996 Mar;45(3):354-60.PMID: 8593942 [PubMed - indexed for MEDLINE]Related articles

    17.

    Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity.

    Dresner A, Laurent D, Marcucci M, Griffin ME, Dufour S, Cline GW, Slezak LA, Andersen DK, Hundal RS, Rothman DL, Petersen KF, Shulman GI.

    J Clin Invest. 1999 Jan;103(2):253-9.PMID: 9916137 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Effect of fatty acids on glucose production and utilization in man.

    Ferrannini E, Barrett EJ, Bevilacqua S, DeFronzo RA.

    J Clin Invest. 1983 Nov;72(5):1737-47.PMID: 6138367 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Evidence against a role for insulin-signaling proteins PI 3-kinase and Akt in insulin resistance in human skeletal muscle induced by short-term GH infusion.

    Jessen N, Djurhuus CB, Jørgensen JO, Jensen LS, Møller N, Lund S, Schmitz O.

    Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E194-9. Epub 2004 Aug 31.PMID: 15339744 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha.

    Itani SI, Ruderman NB, Schmieder F, Boden G.

    Diabetes. 2002 Jul;51(7):2005-11.PMID: 12086926 [PubMed - indexed for MEDLINE]Related articlesFree article

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