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    Results: 1 to 20 of 101

    1.

    Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis.

    Elkon R, Rashi-Elkeles S, Lerenthal Y, Linhart C, Tenne T, Amariglio N, Rechavi G, Shamir R, Shiloh Y.

    Genome Biol. 2005;6(5):R43. Epub 2005 Apr 13.

    PMID:
    15892871
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    ATM-dependent activation of the gene encoding MAP kinase phosphatase 5 by radiomimetic DNA damage.

    Bar-Shira A, Rashi-Elkeles S, Zlochover L, Moyal L, Smorodinsky NI, Seger R, Shiloh Y.

    Oncogene. 2002 Jan 24;21(5):849-55.

    PMID:
    11850813
    [PubMed - indexed for MEDLINE]
    Free Article
    3.

    Identification of new Rel/NFkappaB regulatory networks by focused genome location analysis.

    De Siervi A, De Luca P, Moiola C, Gueron G, Tongbai R, Chandramouli GV, Haggerty C, Dzekunova I, Petersen D, Kawasaki E, Kil WJ, Camphausen K, Longo D, Gardner K.

    Cell Cycle. 2009 Jul 1;8(13):2093-100. Epub 2009 Jul 5.

    PMID:
    19502793
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Parallel induction of ATM-dependent pro- and antiapoptotic signals in response to ionizing radiation in murine lymphoid tissue.

    Rashi-Elkeles S, Elkon R, Weizman N, Linhart C, Amariglio N, Sternberg G, Rechavi G, Barzilai A, Shamir R, Shiloh Y.

    Oncogene. 2006 Mar 9;25(10):1584-92.

    PMID:
    16314843
    [PubMed - indexed for MEDLINE]
    5.

    The radiomimetic enediyne C-1027 induces unusual DNA damage responses to double-strand breaks.

    Kennedy DR, Beerman TA.

    Biochemistry. 2006 Mar 21;45(11):3747-54.

    PMID:
    16533058
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    7.

    Persistence of unrepaired DNA double strand breaks caused by inhibition of ATM does not lead to radio-sensitisation in the absence of NF-κB activation.

    Veuger SJ, Durkacz BW.

    DNA Repair (Amst). 2011 Feb 7;10(2):235-44. Epub 2010 Dec 8.

    PMID:
    21144805
    [PubMed - indexed for MEDLINE]
    8.

    Final Report on Carcinogens Background Document for Formaldehyde.

    National Toxicology Program.

    Rep Carcinog Backgr Doc. 2010 Jan;(10-5981):i-512.

    PMID:
    20737003
    [PubMed - as supplied by publisher]
    9.

    hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage.

    Moumen A, Masterson P, O'Connor MJ, Jackson SP.

    Cell. 2005 Dec 16;123(6):1065-78.

    PMID:
    16360036
    [PubMed - indexed for MEDLINE]
    10.

    ATM-dependent IGF-1 induction regulates secretory clusterin expression after DNA damage and in genetic instability.

    Goetz EM, Shankar B, Zou Y, Morales JC, Luo X, Araki S, Bachoo R, Mayo LD, Boothman DA.

    Oncogene. 2011 Sep 1;30(35):3745-54. doi: 10.1038/onc.2011.92. Epub 2011 Apr 4.

    PMID:
    21460853
    [PubMed - indexed for MEDLINE]
    11.

    RNA silencing of checkpoint regulators sensitizes p53-defective prostate cancer cells to chemotherapy while sparing normal cells.

    Mukhopadhyay UK, Senderowicz AM, Ferbeyre G.

    Cancer Res. 2005 Apr 1;65(7):2872-81.

    PMID:
    15805289
    [PubMed - indexed for MEDLINE]
    Free Article
    12.

    Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.

    Pereg Y, Shkedy D, de Graaf P, Meulmeester E, Edelson-Averbukh M, Salek M, Biton S, Teunisse AF, Lehmann WD, Jochemsen AG, Shiloh Y.

    Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):5056-61. Epub 2005 Mar 23.

    PMID:
    15788536
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    13.

    ATM localization and gene expression in the adult mouse eye.

    Leemput J, Masson C, Bigot K, Errachid A, Dansault A, Provost A, Gadin S, Aoufouchi S, Menasche M, Abitbol M.

    Mol Vis. 2009;15:393-416. Epub 2009 Feb 20.

    PMID:
    19234633
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses.

    Stankovic T, Hubank M, Cronin D, Stewart GS, Fletcher D, Bignell CR, Alvi AJ, Austen B, Weston VJ, Fegan C, Byrd PJ, Moss PA, Taylor AM.

    Blood. 2004 Jan 1;103(1):291-300. Epub 2003 Sep 4.

    PMID:
    12958068
    [PubMed - indexed for MEDLINE]
    Free Article
    15.

    Transcriptional modulation induced by ionizing radiation: p53 remains a central player.

    Rashi-Elkeles S, Elkon R, Shavit S, Lerenthal Y, Linhart C, Kupershtein A, Amariglio N, Rechavi G, Shamir R, Shiloh Y.

    Mol Oncol. 2011 Aug;5(4):336-48. Epub 2011 Jul 7. Review.

    PMID:
    21795128
    [PubMed - indexed for MEDLINE]
    16.

    Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.

    Kang J, Ferguson D, Song H, Bassing C, Eckersdorff M, Alt FW, Xu Y.

    Mol Cell Biol. 2005 Jan;25(2):661-70.

    PMID:
    15632067
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Implication of checkpoint kinase-dependent up-regulation of ribonucleotide reductase R2 in DNA damage response.

    Zhang YW, Jones TL, Martin SE, Caplen NJ, Pommier Y.

    J Biol Chem. 2009 Jul 3;284(27):18085-95. Epub 2009 May 5.

    PMID:
    19416980
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    Upregulated ATM gene expression and activated DNA crosslink-induced damage response checkpoint in Fanconi anemia: implications for carcinogenesis.

    Yamamoto K, Nihrane A, Aglipay J, Sironi J, Arkin S, Lipton JM, Ouchi T, Liu JM.

    Mol Med. 2008 Mar-Apr;14(3-4):167-74.

    PMID:
    18224251
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Deficiency in the catalytic subunit of DNA-dependent protein kinase causes down-regulation of ATM.

    Peng Y, Woods RG, Beamish H, Ye R, Lees-Miller SP, Lavin MF, Bedford JS.

    Cancer Res. 2005 Mar 1;65(5):1670-7.

    PMID:
    15753361
    [PubMed - indexed for MEDLINE]
    Free Article
    20.

    Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53.

    Turenne GA, Paul P, Laflair L, Price BD.

    Oncogene. 2001 Aug 23;20(37):5100-10.

    PMID:
    11526498
    [PubMed - indexed for MEDLINE]
    Free Article

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