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Inhibitory effects of antipsychotics on carbachol-enhanced insulin secretion from perifused rat islets: role of muscarinic antagonism in antipsychotic-induced diabetes and hyperglycemia.

Johnson DE, Yamazaki H, Ward KM, Schmidt AW, Lebel WS, Treadway JL, Gibbs EM, Zawalich WS, Rollema H.

Diabetes. 2005 May;54(5):1552-8.PMID: 15855345 [PubMed - indexed for MEDLINE]Related articlesFree article

The atypical antipsychotic clozapine impairs insulin secretion by inhibiting glucose metabolism and distal steps in rat pancreatic islets.

Sasaki N, Iwase M, Uchizono Y, Nakamura U, Imoto H, Abe S, Iida M.

Diabetologia. 2006 Dec;49(12):2930-8. Epub 2006 Oct 27.PMID: 17072584 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-1 stimulates insulin secretion but not phosphoinositide hydrolysis from islets desensitized by prior exposure to high glucose or the muscarinic agonist carbachol.

Zawalich WS, Zawalich KC.

Metabolism. 1996 Feb;45(2):273-8.PMID: 8596502 [PubMed - indexed for MEDLINE]Related articles

Time-dependent effects of cholinergic stimulation on beta cell responsiveness.

Zawalich WS, Zawalich KC, Kelley GG.

Pflugers Arch. 1996 Aug;432(4):589-96.PMID: 8764958 [PubMed - indexed for MEDLINE]Related articles

Clozapine and olanzapine, but not conventional antipsychotics, increase insulin release in vitro.

Melkersson K.

Eur Neuropsychopharmacol. 2004 Mar;14(2):115-9.PMID: 15013026 [PubMed - indexed for MEDLINE]Related articles

Effects of protein kinase C inhibitors on insulin secretory responses from rodent pancreatic islets.

Zawalich WS, Zawalich KC.

Mol Cell Endocrinol. 2001 May 25;177(1-2):95-105.PMID: 11377825 [PubMed - indexed for MEDLINE]Related articles

Increased insulin secretion by muscarinic M1 and M3 receptor function from rat pancreatic islets in vitro.

Renuka TR, Robinson R, Paulose CS.

Neurochem Res. 2006 Mar;31(3):313-20. Epub 2006 May 3.PMID: 16733808 [PubMed - indexed for MEDLINE]Related articles

Wortmannin inhibits insulin secretion in pancreatic islets and beta-TC3 cells independent of its inhibition of phosphatidylinositol 3-kinase.

Gao Z, Konrad RJ, Collins H, Matschinsky FM, Rothenberg PL, Wolf BA.

Diabetes. 1996 Jul;45(7):854-62.PMID: 8666133 [PubMed - indexed for MEDLINE]Related articles

Biphasic insulin secretion from freshly isolated or cultured, perifused rodent islets: comparative studies with rats and mice.

Zawalich WS, Yamazaki H, Zawalich KC.

Metabolism. 2008 Jan;57(1):30-9.PMID: 18078856 [PubMed - indexed for MEDLINE]Related articlesFree article

Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review.

Newcomer JW.

CNS Drugs. 2005;19 Suppl 1:1-93. Review.PMID: 15998156 [PubMed - indexed for MEDLINE]Related articles

Effects of short-term culturing on islet phosphoinositide and insulin secretory responses to glucose and carbachol.

Zawalich WS, Zawalich KC, Kelley GG.

Acta Diabetol. 1995 Oct;32(3):158-64.PMID: 8590784 [PubMed - indexed for MEDLINE]Related articles

The antipsychotics clozapine and olanzapine increase plasma glucose and corticosterone levels in rats: comparison with aripiprazole, ziprasidone, bifeprunox and F15063.

Assié MB, Carilla-Durand E, Bardin L, Maraval M, Aliaga M, Malfètes N, Barbara M, Newman-Tancredi A.

Eur J Pharmacol. 2008 Sep 11;592(1-3):160-6. Epub 2008 Jul 4.PMID: 18640111 [PubMed - indexed for MEDLINE]Related articles

Acute and chronic effects of glucose and carbachol on insulin secretion and phospholipase C activation: studies with diazoxide and atropine.

Yamazaki H, Philbrick W, Zawalich KC, Zawalich WS.

Am J Physiol Endocrinol Metab. 2006 Jan;290(1):E26-E33. Epub 2005 Aug 16.PMID: 16105864 [PubMed - indexed for MEDLINE]Related articlesFree article

Dexamethasone suppresses phospholipase C activation and insulin secretion from isolated rat islets.

Zawalich WS, Tesz GJ, Yamazaki H, Zawalich KC, Philbrick W.

Metabolism. 2006 Jan;55(1):35-42.PMID: 16324917 [PubMed - indexed for MEDLINE]Related articles

Regulation of insulin release by phospholipase C activation in mouse islets: differential effects of glucose and neurohumoral stimulation.

Zawalich WS, Zawalich KC, Kelley GG.

Endocrinology. 1995 Nov;136(11):4903-9.PMID: 7588223 [PubMed - indexed for MEDLINE]Related articles

Evidence that hyperglycemia increases muscarinic binding in pancreatic islets of the rat.

Ostenson CG, Grill V.

Endocrinology. 1987 Nov;121(5):1705-10.PMID: 3311716 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance and secretion in vivo: effects of different antipsychotics in an animal model.

Chintoh AF, Mann SW, Lam L, Giacca A, Fletcher P, Nobrega J, Remington G.

Schizophr Res. 2009 Mar;108(1-3):127-33. Epub 2009 Jan 20.PMID: 19157785 [PubMed - indexed for MEDLINE]Related articles

The atypical antipsychotics quetiapine, risperidone and ziprasidone do not increase insulin release in vitro.

Melkersson K, Jansson E.

Neuro Endocrinol Lett. 2005 Jun;26(3):205-8.PMID: 15990722 [PubMed - indexed for MEDLINE]Related articles

Effects of glucose, exogenous insulin, and carbachol on C-peptide and insulin secretion from isolated perifused rat islets.

Zawalich WS, Zawalich KC.

J Biol Chem. 2002 Jul 19;277(29):26233-7. Epub 2002 May 13.PMID: 12011082 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of the atypical antipsychotic clozapine on insulin release in vitro.

Melkersson K, Jansson E.

Neuro Endocrinol Lett. 2007 Dec;28(6):854-60.PMID: 18063937 [PubMed - indexed for MEDLINE]Related articles