PubMed

Low-dose poly(ADP-ribose) polymerase inhibitor-containing combination therapies reverse early peripheral diabetic neuropathy.

Li F, Drel VR, Szabó C, Stevens MJ, Obrosova IG.

Diabetes. 2005 May;54(5):1514-22.PMID: 15855340 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of orally active poly(ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy.

Li F, Szabó C, Pacher P, Southan GJ, Abatan OI, Charniauskaya T, Stevens MJ, Obrosova IG.

Diabetologia. 2004 Apr;47(4):710-7.PMID: 15298348 [PubMed - indexed for MEDLINE]Related articles

Nicotinamide reverses neurological and neurovascular deficits in streptozotocin diabetic rats.

Stevens MJ, Li F, Drel VR, Abatan OI, Kim H, Burnett D, Larkin D, Obrosova IG.

J Pharmacol Exp Ther. 2007 Jan;320(1):458-64. Epub 2006 Oct 4.PMID: 17021258 [PubMed - indexed for MEDLINE]Related articlesFree article

Poly(ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy.

Ilnytska O, Lyzogubov VV, Stevens MJ, Drel VR, Mashtalir N, Pacher P, Yorek MA, Obrosova IG.

Diabetes. 2006 Jun;55(6):1686-94.PMID: 16731831 [PubMed - indexed for MEDLINE]Related articlesFree article

Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications.

Obrosova IG, Pacher P, Szabó C, Zsengeller Z, Hirooka H, Stevens MJ, Yorek MA.

Diabetes. 2005 Jan;54(1):234-42.PMID: 15616034 [PubMed - indexed for MEDLINE]Related articlesFree article

Poly(ADP-ribose)polymerase inhibition counteracts cataract formation and early retinal changes in streptozotocin-diabetic rats.

Drel VR, Xu W, Zhang J, Kador PF, Ali TK, Shin J, Julius U, Slusher B, El-Remessy AB, Obrosova IG.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1778-90. Epub 2008 Dec 20.PMID: 19098320 [PubMed - indexed for MEDLINE]Related articles

Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy.

Obrosova IG, Li F, Abatan OI, Forsell MA, Komjáti K, Pacher P, Szabó C, Stevens MJ.

Diabetes. 2004 Mar;53(3):711-20.PMID: 14988256 [PubMed - indexed for MEDLINE]Related articlesFree article

PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy.

Obrosova IG, Xu W, Lyzogubov VV, Ilnytska O, Mashtalir N, Vareniuk I, Pavlov IA, Zhang J, Slusher B, Drel VR.

Free Radic Biol Med. 2008 Mar 15;44(6):972-81. Epub 2007 Oct 3.PMID: 17976390 [PubMed - indexed for MEDLINE]Related articles

Protective effects of 4-amino1,8-napthalimide, a poly (ADP-ribose) polymerase inhibitor in experimental diabetic neuropathy.

Sharma SS, Kumar A, Kaundal RK.

Life Sci. 2008 Mar 12;82(11-12):570-6. Epub 2007 Dec 26.PMID: 18262571 [PubMed - indexed for MEDLINE]Related articles

Role of nitrosative stress in early neuropathy and vascular dysfunction in streptozotocin-diabetic rats.

Obrosova IG, Drel VR, Oltman CL, Mashtalir N, Tibrewala J, Groves JT, Yorek MA.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1645-55. Epub 2007 Oct 2.PMID: 17911342 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative-nitrosative stress and poly(ADP-ribose) polymerase (PARP) activation in experimental diabetic neuropathy: the relation is revisited.

Obrosova IG, Drel VR, Pacher P, Ilnytska O, Wang ZQ, Stevens MJ, Yorek MA.

Diabetes. 2005 Dec;54(12):3435-41.PMID: 16306359 [PubMed - indexed for MEDLINE]Related articlesFree article

Poly(ADP-ribosyl)ation enhancement in brain cell nuclei is associated with diabetic neuropathy.

Kuchmerovska T, Shymanskyy I, Donchenko G, Kuchmerovskyy M, Pakirbaieva L, Klimenko A.

J Diabetes Complications. 2004 Jul-Aug;18(4):198-204.PMID: 15207836 [PubMed - indexed for MEDLINE]Related articles

Evaluation of the peroxynitrite decomposition catalyst Fe(III) tetra-mesitylporphyrin octasulfonate on peripheral neuropathy in a mouse model of type 1 diabetes.

Drel VR, Pacher P, Vareniuk I, Pavlov IA, Ilnytska O, Lyzogubov VV, Bell SR, Groves JT, Obrosova IG.

Int J Mol Med. 2007 Dec;20(6):783-92.PMID: 17982684 [PubMed - indexed for MEDLINE]Related articlesFree article

The leptin-deficient (ob/ob) mouse: a new animal model of peripheral neuropathy of type 2 diabetes and obesity.

Drel VR, Mashtalir N, Ilnytska O, Shin J, Li F, Lyzogubov VV, Obrosova IG.

Diabetes. 2006 Dec;55(12):3335-43.PMID: 17130477 [PubMed - indexed for MEDLINE]Related articlesFree article

Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression.

Obrosova IG, Minchenko AG, Frank RN, Seigel GM, Zsengeller Z, Pacher P, Stevens MJ, Szabó C.

Int J Mol Med. 2004 Jul;14(1):55-64.PMID: 15202016 [PubMed - indexed for MEDLINE]Related articles

Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation.

Minchenko AG, Stevens MJ, White L, Abatan OI, Komjáti K, Pacher P, Szabó C, Obrosova IG.

FASEB J. 2003 Aug;17(11):1514-6. Epub 2003 Jun 3.PMID: 12824290 [PubMed - indexed for MEDLINE]Related articlesFree article

A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin-diabetic mice.

Drel VR, Pacher P, Vareniuk I, Pavlov I, Ilnytska O, Lyzogubov VV, Tibrewala J, Groves JT, Obrosova IG.

Eur J Pharmacol. 2007 Aug 13;569(1-2):48-58. Epub 2007 Jun 9.PMID: 17644085 [PubMed - indexed for MEDLINE]Related articlesFree article

Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells.

Drel VR, Pacher P, Stevens MJ, Obrosova IG.

Free Radic Biol Med. 2006 Apr 15;40(8):1454-65. Epub 2006 Jan 31.PMID: 16631535 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of the protein kinase C beta inhibitor LY333531 on neural and vascular function in rats with streptozotocin-induced diabetes.

Cotter MA, Jack AM, Cameron NE.

Clin Sci (Lond). 2002 Sep;103(3):311-21.PMID: 12193157 [PubMed - indexed for MEDLINE]Related articles

Depletion of taurine in experimental diabetic neuropathy: implications for nerve metabolic, vascular, and functional deficits.

Pop-Busui R, Sullivan KA, Van Huysen C, Bayer L, Cao X, Towns R, Stevens MJ.

Exp Neurol. 2001 Apr;168(2):259-72.PMID: 11259114 [PubMed - indexed for MEDLINE]Related articles