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    Results: 1 to 20 of 375

    1.

    Sphingosine kinase activity and sphingosine-1 phosphate production in rat pancreatic islets and INS-1 cells: response to cytokines.

    Mastrandrea LD, Sessanna SM, Laychock SG.

    Diabetes. 2005 May;54(5):1429-36.PMID: 15855330 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Anti-inflammatory effects of sphingosine kinase modulation in inflammatory arthritis.

    Lai WQ, Irwan AW, Goh HH, Howe HS, Yu DT, Valle-Oñate R, McInnes IB, Melendez AJ, Leung BP.

    J Immunol. 2008 Dec 1;181(11):8010-7.PMID: 19017993 [PubMed - indexed for MEDLINE]Related articles

    3.

    Sphingosine 1-phosphate affects cytokine-induced apoptosis in rat pancreatic islet beta-cells.

    Laychock SG, Sessanna SM, Lin MH, Mastrandrea LD.

    Endocrinology. 2006 Oct;147(10):4705-12. Epub 2006 Jun 22.PMID: 16794003 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Basal and induced sphingosine kinase 1 activity in A549 carcinoma cells: function in cell survival and IL-1beta and TNF-alpha induced production of inflammatory mediators.

    Billich A, Bornancin F, Mechtcheriakova D, Natt F, Huesken D, Baumruker T.

    Cell Signal. 2005 Oct;17(10):1203-17. Epub 2005 Jan 18.PMID: 16038795 [PubMed - indexed for MEDLINE]Related articles

    5.

    The sphingosine kinase 1/sphingosine-1-phosphate pathway mediates COX-2 induction and PGE2 production in response to TNF-alpha.

    Pettus BJ, Bielawski J, Porcelli AM, Reames DL, Johnson KR, Morrow J, Chalfant CE, Obeid LM, Hannun YA.

    FASEB J. 2003 Aug;17(11):1411-21.PMID: 12890694 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.

    Hong TP, Andersen NA, Nielsen K, Karlsen AE, Fantuzzi G, Eizirik DL, Dinarello CA, Mandrup-Poulsen T.

    Eur Cytokine Netw. 2000 Jun;11(2):193-205.PMID: 10903798 [PubMed - indexed for MEDLINE]Related articles

    8.

    Sphingosine kinase, sphingosine-1-phosphate, and apoptosis.

    Maceyka M, Payne SG, Milstien S, Spiegel S.

    Biochim Biophys Acta. 2002 Dec 30;1585(2-3):193-201. Review.PMID: 12531554 [PubMed - indexed for MEDLINE]Related articles

    9.

    Metallothionein induction in islets of Langerhans and insulinoma cells.

    Laychock SG, Duzen J, Simpkins CO.

    Mol Cell Endocrinol. 2000 Jul 25;165(1-2):179-87.PMID: 10940496 [PubMed - indexed for MEDLINE]Related articles

    10.

    Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells.

    Xia P, Wang L, Gamble JR, Vadas MA.

    J Biol Chem. 1999 Nov 26;274(48):34499-505.PMID: 10567432 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Hypoxia enhances sphingosine kinase 2 activity and provokes sphingosine-1-phosphate-mediated chemoresistance in A549 lung cancer cells.

    Schnitzer SE, Weigert A, Zhou J, Brüne B.

    Mol Cancer Res. 2009 Mar;7(3):393-401. Epub 2009 Feb 24.PMID: 19240180 [PubMed - indexed for MEDLINE]Related articles

    12.

    Endothelial differentiation gene receptors in pancreatic islets and INS-1 cells.

    Laychock SG, Tian Y, Sessanna SM.

    Diabetes. 2003 Aug;52(8):1986-93.PMID: 12882914 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Sphingosine kinase 1 (SPHK1) is induced by transforming growth factor-beta and mediates TIMP-1 up-regulation.

    Yamanaka M, Shegogue D, Pei H, Bu S, Bielawska A, Bielawski J, Pettus B, Hannun YA, Obeid L, Trojanowska M.

    J Biol Chem. 2004 Dec 24;279(52):53994-4001. Epub 2004 Oct 12.PMID: 15485866 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Sphingosine 1-phosphate phosphatase 2 is induced during inflammatory responses.

    Mechtcheriakova D, Wlachos A, Sobanov J, Kopp T, Reuschel R, Bornancin F, Cai R, Zemann B, Urtz N, Stingl G, Zlabinger G, Woisetschläger M, Baumruker T, Billich A.

    Cell Signal. 2007 Apr;19(4):748-60. Epub 2006 Sep 30.PMID: 17113265 [PubMed - indexed for MEDLINE]Related articles

    15.

    Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation.

    Kohno M, Momoi M, Oo ML, Paik JH, Lee YM, Venkataraman K, Ai Y, Ristimaki AP, Fyrst H, Sano H, Rosenberg D, Saba JD, Proia RL, Hla T.

    Mol Cell Biol. 2006 Oct;26(19):7211-23.PMID: 16980623 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Differential regulation of sphingosine kinases 1 and 2 in lung injury.

    Wadgaonkar R, Patel V, Grinkina N, Romano C, Liu J, Zhao Y, Sammani S, Garcia JG, Natarajan V.

    Am J Physiol Lung Cell Mol Physiol. 2009 Apr;296(4):L603-13. Epub 2009 Jan 23.PMID: 19168577 [PubMed - indexed for MEDLINE]Related articles

    17.

    Distribution of sphingosine kinase activity and mRNA in rodent brain.

    Blondeau N, Lai Y, Tyndall S, Popolo M, Topalkara K, Pru JK, Zhang L, Kim H, Liao JK, Ding K, Waeber C.

    J Neurochem. 2007 Oct;103(2):509-17. Epub 2007 Jul 10.PMID: 17623044 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling.

    Hong JH, Youm JK, Kwon MJ, Park BD, Lee YM, Lee SI, Shin DM, Lee SH.

    J Invest Dermatol. 2008 Sep;128(9):2166-78. Epub 2008 Apr 3.PMID: 18385762 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    The role of sphingosine 1-phosphate in the TNF-alpha induction of IL-8 gene expression in lung epithelial cells.

    Chandru H, Boggaram V.

    Gene. 2007 Apr 15;391(1-2):150-60. Epub 2006 Dec 22.PMID: 17306937 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Tumor necrosis factor-alpha-stimulated cell proliferation is mediated through sphingosine kinase-dependent Akt activation and cyclin D expression.

    Radeff-Huang J, Seasholtz TM, Chang JW, Smith JM, Walsh CT, Brown JH.

    J Biol Chem. 2007 Jan 12;282(2):863-70. Epub 2006 Nov 19.PMID: 17114809 [PubMed - indexed for MEDLINE]Related articlesFree article

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