PubMed

The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans.

Andrew R, Westerbacka J, Wahren J, Yki-Järvinen H, Walker BR.

Diabetes. 2005 May;54(5):1364-70.PMID: 15855321 [PubMed - indexed for MEDLINE]Related articlesFree article

Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans.

Stimson RH, Andersson J, Andrew R, Redhead DN, Karpe F, Hayes PC, Olsson T, Walker BR.

Diabetes. 2009 Jan;58(1):46-53. Epub 2008 Oct 13.PMID: 18852329 [PubMed - indexed for MEDLINE]Related articlesFree article

Body fat distribution and cortisol metabolism in healthy men: enhanced 5beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver.

Westerbacka J, Yki-Järvinen H, Vehkavaara S, Häkkinen AM, Andrew R, Wake DJ, Seckl JR, Walker BR.

J Clin Endocrinol Metab. 2003 Oct;88(10):4924-31.PMID: 14557475 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11beta-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone.

Sandeep TC, Andrew R, Homer NZ, Andrews RC, Smith K, Walker BR.

Diabetes. 2005 Mar;54(3):872-9.PMID: 15734867 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue production of cortisol by 11beta-hydroxysteroid dehydrogenase type 1 and metabolic disease.

Walker BR, Andrew R.

Ann N Y Acad Sci. 2006 Nov;1083:165-84. Review.PMID: 17148739 [PubMed - indexed for MEDLINE]Related articles

Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonists on 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue in men.

Wake DJ, Stimson RH, Tan GD, Homer NZ, Andrew R, Karpe F, Walker BR.

J Clin Endocrinol Metab. 2007 May;92(5):1848-56. Epub 2007 Feb 27.PMID: 17327378 [PubMed - indexed for MEDLINE]Related articlesFree article

Splanchnic cortisol production in dogs occurs primarily in the liver: evidence for substantial hepatic specific 11beta hydroxysteroid dehydrogenase type 1 activity.

Basu R, Edgerton DS, Singh RJ, Cherrington A, Rizza RA.

Diabetes. 2006 Nov;55(11):3013-9.PMID: 17065337 [PubMed - indexed for MEDLINE]Related articlesFree article

Splanchnic cortisol production occurs in humans: evidence for conversion of cortisone to cortisol via the 11-beta hydroxysteroid dehydrogenase (11beta-hsd) type 1 pathway.

Basu R, Singh RJ, Basu A, Chittilapilly EG, Johnson CM, Toffolo G, Cobelli C, Rizza RA.

Diabetes. 2004 Aug;53(8):2051-9.PMID: 15277385 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute in vivo regulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by insulin and intralipid infusions in humans.

Wake DJ, Homer NZ, Andrew R, Walker BR.

J Clin Endocrinol Metab. 2006 Nov;91(11):4682-8. Epub 2006 Sep 5.PMID: 16954164 [PubMed - indexed for MEDLINE]Related articlesFree article

Local and systemic impact of transcriptional up-regulation of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue in human obesity.

Wake DJ, Rask E, Livingstone DE, Söderberg S, Olsson T, Walker BR.

J Clin Endocrinol Metab. 2003 Aug;88(8):3983-8.PMID: 12915696 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of nutrient ingestion on total-body and splanchnic cortisol production in humans.

Basu R, Singh R, Basu A, Johnson CM, Rizza RA.

Diabetes. 2006 Mar;55(3):667-74.PMID: 16505229 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity and type 2 diabetes do not alter splanchnic cortisol production in humans.

Basu R, Singh RJ, Basu A, Chittilapilly EG, Johnson MC, Toffolo G, Cobelli C, Rizza RA.

J Clin Endocrinol Metab. 2005 Jul;90(7):3919-26. Epub 2005 Apr 5.PMID: 15811928 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 in obesity.

Wake DJ, Walker BR.

Endocrine. 2006 Feb;29(1):101-8. Review.PMID: 16622297 [PubMed - indexed for MEDLINE]Related articles

Liver is the site of splanchnic cortisol production in obese nondiabetic humans.

Basu R, Basu A, Grudzien M, Jung P, Jacobson P, Johnson M, Singh R, Sarr M, Rizza RA.

Diabetes. 2009 Jan;58(1):39-45. Epub 2008 Oct 13. Erratum in: Diabetes. 2009 Aug;58(8):1936. PMID: 18852327 [PubMed - indexed for MEDLINE]Related articlesFree article

11beta-hydroxysteroid dehydrogenase type 1 and obesity.

Morton NM, Seckl JR.

Front Horm Res. 2008;36:146-64. Review.PMID: 18230901 [PubMed - indexed for MEDLINE]Related articles

In vivo activity of 11beta-hydroxysteroid dehydrogenase type 1 and free fatty acid-induced insulin resistance.

Mai K, Kullmann V, Bobbert T, Maser-Gluth C, Möhlig M, Bähr V, Pfeiffer AF, Spranger J, Diederich S.

Clin Endocrinol (Oxf). 2005 Oct;63(4):442-9.PMID: 16181237 [PubMed - indexed for MEDLINE]Related articles

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 activity in vivo limits glucocorticoid exposure to human adipose tissue and decreases lipolysis.

Tomlinson JW, Sherlock M, Hughes B, Hughes SV, Kilvington F, Bartlett W, Courtney R, Rejto P, Carley W, Stewart PM.

J Clin Endocrinol Metab. 2007 Mar;92(3):857-64. Epub 2007 Jan 2.PMID: 17200165 [PubMed - indexed for MEDLINE]Related articlesFree article

11 beta-hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome.

Wake DJ, Walker BR.

Mol Cell Endocrinol. 2004 Feb 27;215(1-2):45-54. Review.PMID: 15026174 [PubMed - indexed for MEDLINE]Related articles

Extra-adrenal regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1: physiological regulator and pharmacological target for energy partitioning.

Walker BR.

Proc Nutr Soc. 2007 Feb;66(1):1-8.PMID: 17343766 [PubMed - indexed for MEDLINE]Related articles

11beta-Hydroxysteroid dehydrogenase type 1-driven cortisone reactivation regulates plasminogen activator inhibitor type 1 in adipose tissue of obese women.

Ayachi SE, Paulmyer-Lacroix O, Verdier M, Alessi MC, Dutour A, Grino M.

J Thromb Haemost. 2006 Mar;4(3):621-7.PMID: 16460444 [PubMed - indexed for MEDLINE]Related articles