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    Results: 1 to 20 of 254

    1.

    A role for iNOS in fasting hyperglycemia and impaired insulin signaling in the liver of obese diabetic mice.

    Fujimoto M, Shimizu N, Kunii K, Martyn JA, Ueki K, Kaneki M.

    Diabetes. 2005 May;54(5):1340-8.PMID: 15855318 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Inducible nitric-oxide synthase and NO donor induce insulin receptor substrate-1 degradation in skeletal muscle cells.

    Sugita H, Fujimoto M, Yasukawa T, Shimizu N, Sugita M, Yasuhara S, Martyn JA, Kaneki M.

    J Biol Chem. 2005 Apr 8;280(14):14203-11. Epub 2005 Feb 1.PMID: 15805118 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Acute physical exercise reverses S-nitrosation of the insulin receptor, insulin receptor substrate 1 and protein kinase B/Akt in diet-induced obese Wistar rats.

    Pauli JR, Ropelle ER, Cintra DE, Carvalho-Filho MA, Moraes JC, De Souza CT, Velloso LA, Carvalheira JB, Saad MJ.

    J Physiol. 2008 Jan 15;586(2):659-71. Epub 2007 Nov 1.PMID: 17974582 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance.

    Saad MJ, Araki E, Miralpeix M, Rothenberg PL, White MF, Kahn CR.

    J Clin Invest. 1992 Nov;90(5):1839-49.PMID: 1331176 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Chronic blockade of nitric oxide synthesis reduces adiposity and improves insulin resistance in high fat-induced obese mice.

    Tsuchiya K, Sakai H, Suzuki N, Iwashima F, Yoshimoto T, Shichiri M, Hirata Y.

    Endocrinology. 2007 Oct;148(10):4548-56. Epub 2007 Jun 21.PMID: 17584959 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Targeted disruption of iNOS prevents LPS-induced S-nitrosation of IRbeta/IRS-1 and Akt and insulin resistance in muscle of mice.

    Carvalho-Filho MA, Ueno M, Carvalheira JB, Velloso LA, Saad MJ.

    Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E476-82. Epub 2006 Apr 25.PMID: 16638822 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states.

    Standaert ML, Sajan MP, Miura A, Kanoh Y, Chen HC, Farese RV Jr, Farese RV.

    J Biol Chem. 2004 Jun 11;279(24):24929-34. Epub 2004 Apr 6.PMID: 15069067 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance.

    Sugita H, Kaneki M, Tokunaga E, Sugita M, Koike C, Yasuhara S, Tompkins RG, Martyn JA.

    Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E386-94.PMID: 11788371 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse.

    Kerouz NJ, Hörsch D, Pons S, Kahn CR.

    J Clin Invest. 1997 Dec 15;100(12):3164-72.PMID: 9399964 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    S-nitrosylation-dependent inactivation of Akt/protein kinase B in insulin resistance.

    Yasukawa T, Tokunaga E, Ota H, Sugita H, Martyn JA, Kaneki M.

    J Biol Chem. 2005 Mar 4;280(9):7511-8. Epub 2005 Jan 4.PMID: 15632167 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Inducible nitric oxide synthase activity and expression in liver and hepatocytes of diabetic rats.

    Madar Z, Kalet-Litman S, Stark AH.

    Pharmacology. 2005 Feb;73(2):106-12. Epub 2004 Nov 4.PMID: 15528954 [PubMed - indexed for MEDLINE]Related articles

    12.

    Sequential phosphorylation of insulin receptor substrate-2 by glycogen synthase kinase-3 and c-Jun NH2-terminal kinase plays a role in hepatic insulin signaling.

    Sharfi H, Eldar-Finkelman H.

    Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E307-15. Epub 2007 Nov 20.PMID: 18029441 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle.

    Perreault M, Marette A.

    Nat Med. 2001 Oct;7(10):1138-43.PMID: 11590438 [PubMed - indexed for MEDLINE]Related articles

    14.

    Role of inducible nitric oxide synthase in induction of RhoA expression in hearts from diabetic rats.

    Soliman H, Craig GP, Nagareddy P, Yuen VG, Lin G, Kumar U, McNeill JH, Macleod KM.

    Cardiovasc Res. 2008 Jul 15;79(2):322-30. Epub 2008 Apr 14.PMID: 18411229 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRbeta/IRS-1 and Akt.

    Carvalho-Filho MA, Ropelle ER, Pauli RJ, Cintra DE, Tsukumo DM, Silveira LR, Curi R, Carvalheira JB, Velloso LA, Saad MJ.

    Diabetologia. 2009 Sep 3. [Epub ahead of print]PMID: 19730809 [PubMed - as supplied by publisher]Related articles

    16.

    Selective inhibition of protein kinase C beta(2) attenuates inducible nitric oxide synthase-mediated cardiovascular abnormalities in streptozotocin-induced diabetic rats.

    Nagareddy PR, Soliman H, Lin G, Rajput PS, Kumar U, McNeill JH, MacLeod KM.

    Diabetes. 2009 Oct;58(10):2355-64. Epub 2009 Jul 8.PMID: 19587355 [PubMed - indexed for MEDLINE]Related articles

    17.

    Reduction of low molecular weight protein-tyrosine phosphatase expression improves hyperglycemia and insulin sensitivity in obese mice.

    Pandey SK, Yu XX, Watts LM, Michael MD, Sloop KW, Rivard AR, Leedom TA, Manchem VP, Samadzadeh L, McKay RA, Monia BP, Bhanot S.

    J Biol Chem. 2007 May 11;282(19):14291-9. Epub 2007 Mar 12.PMID: 17353188 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Phosphoenolpyruvate carboxykinase (GTP) gene transcription and hyperglycemia are regulated by glucocorticoids in genetically obese db/db transgenic mice.

    Friedman JE, Sun Y, Ishizuka T, Farrell CJ, McCormack SE, Herron LM, Hakimi P, Lechner P, Yun JS.

    J Biol Chem. 1997 Dec 12;272(50):31475-81.PMID: 9395482 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.

    Dentin R, Benhamed F, Hainault I, Fauveau V, Foufelle F, Dyck JR, Girard J, Postic C.

    Diabetes. 2006 Aug;55(8):2159-70.PMID: 16873678 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Leptin activation of corticosterone production in hepatocytes may contribute to the reversal of obesity and hyperglycemia in leptin-deficient ob/ob mice.

    Liu Y, Nakagawa Y, Wang Y, Li R, Li X, Ohzeki T, Friedman TC.

    Diabetes. 2003 Jun;52(6):1409-16.PMID: 12765951 [PubMed - indexed for MEDLINE]Related articlesFree article

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