PubMed

Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta.

Krämer DK, Al-Khalili L, Perrini S, Skogsberg J, Wretenberg P, Kannisto K, Wallberg-Henriksson H, Ehrenborg E, Zierath JR, Krook A.

Diabetes. 2005 Apr;54(4):1157-63.PMID: 15793256 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor (PPAR) alpha and delta and PPAR coactivator 1alpha in human skeletal muscle, but not lipid regulatory genes.

Watt MJ, Southgate RJ, Holmes AG, Febbraio MA.

J Mol Endocrinol. 2004 Oct;33(2):533-44.PMID: 15525607 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of AMP kinase and PPARdelta in the regulation of lipid and glucose metabolism in human skeletal muscle.

Krämer DK, Al-Khalili L, Guigas B, Leng Y, Garcia-Roves PM, Krook A.

J Biol Chem. 2007 Jul 6;282(27):19313-20. Epub 2007 May 11.PMID: 17500064 [PubMed - indexed for MEDLINE]Related articlesFree article

PPARdelta activator GW-501516 has no acute effect on glucose transport in skeletal muscle.

Terada S, Wicke S, Holloszy JO, Han DH.

Am J Physiol Endocrinol Metab. 2006 Apr;290(4):E607-11. Epub 2005 Nov 8.PMID: 16278250 [PubMed - indexed for MEDLINE]Related articlesFree article

The antihyperglycemic drug alpha-lipoic acid stimulates glucose uptake via both GLUT4 translocation and GLUT4 activation: potential role of p38 mitogen-activated protein kinase in GLUT4 activation.

Konrad D, Somwar R, Sweeney G, Yaworsky K, Hayashi M, Ramlal T, Klip A.

Diabetes. 2001 Jun;50(6):1464-71.PMID: 11375349 [PubMed - indexed for MEDLINE]Related articlesFree article

GLUT4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells: potential activation of GLUT4 via p38 mitogen-activated protein kinase.

Somwar R, Kim DY, Sweeney G, Huang C, Niu W, Lador C, Ramlal T, Klip A.

Biochem J. 2001 Nov 1;359(Pt 3):639-49.PMID: 11672439 [PubMed - indexed for MEDLINE]Related articlesFree article

Metformin enhances insulin signalling in insulin-dependent and-independent pathways in insulin resistant muscle cells.

Kumar N, Dey CS.

Br J Pharmacol. 2002 Oct;137(3):329-36.PMID: 12237252 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of a novel non-thiazolidinedione peroxisome proliferator-activated receptor alpha/gamma agonist on glucose uptake.

Hu X, Feng Y, Liu X, Zhao XF, Yu JH, Yang YS, Sydow-Bäckman M, Hörling J, Zierath JR, Leng Y.

Diabetologia. 2007 May;50(5):1048-57. Epub 2007 Mar 1.PMID: 17333104 [PubMed - indexed for MEDLINE]Related articles

The PPARdelta agonist, GW501516, promotes fatty acid oxidation but has no direct effect on glucose utilisation or insulin sensitivity in rat L6 skeletal muscle cells.

Dimopoulos N, Watson M, Green C, Hundal HS.

FEBS Lett. 2007 Oct 2;581(24):4743-8. Epub 2007 Sep 6.PMID: 17869249 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation.

Crunkhorn S, Dearie F, Mantzoros C, Gami H, da Silva WS, Espinoza D, Faucette R, Barry K, Bianco AC, Patti ME.

J Biol Chem. 2007 May 25;282(21):15439-50. Epub 2007 Apr 6.PMID: 17416903 [PubMed - indexed for MEDLINE]Related articlesFree article

MKK6/3 and p38 MAPK pathway activation is not necessary for insulin-induced glucose uptake but regulates glucose transporter expression.

Fujishiro M, Gotoh Y, Katagiri H, Sakoda H, Ogihara T, Anai M, Onishi Y, Ono H, Funaki M, Inukai K, Fukushima Y, Kikuchi M, Oka Y, Asano T.

J Biol Chem. 2001 Jun 8;276(23):19800-6. Epub 2001 Feb 27.PMID: 11279172 [PubMed - indexed for MEDLINE]Related articlesFree article

siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle.

Austin RL, Rune A, Bouzakri K, Zierath JR, Krook A.

Diabetes. 2008 Aug;57(8):2066-73. Epub 2008 Apr 28.PMID: 18443205 [PubMed - indexed for MEDLINE]Related articlesFree article

Sustained exposure of L6 myotubes to high glucose and insulin decreases insulin-stimulated GLUT4 translocation but upregulates GLUT4 activity.

Huang C, Somwar R, Patel N, Niu W, Török D, Klip A.

Diabetes. 2002 Jul;51(7):2090-8.PMID: 12086937 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-stimulated glucose uptake does not require p38 mitogen-activated protein kinase in adipose tissue or skeletal muscle.

Turban S, Beardmore VA, Carr JM, Sakamoto K, Hajduch E, Arthur JS, Hundal HS.

Diabetes. 2005 Nov;54(11):3161-8.PMID: 16249440 [PubMed - indexed for MEDLINE]Related articlesFree article

Eicosapentaenoic acid (20:5 n-3) increases fatty acid and glucose uptake in cultured human skeletal muscle cells.

Aas V, Rokling-Andersen MH, Kase ET, Thoresen GH, Rustan AC.

J Lipid Res. 2006 Feb;47(2):366-74. Epub 2005 Nov 21.PMID: 16301737 [PubMed - indexed for MEDLINE]Related articlesFree article

Arsenite stimulated glucose transport in 3T3-L1 adipocytes involves both Glut4 translocation and p38 MAPK activity.

Bazuine M, Ouwens DM, Gomes de Mesquita DS, Maassen JA.

Eur J Biochem. 2003 Oct;270(19):3891-903.PMID: 14511371 [PubMed - indexed for MEDLINE]Related articlesFree article

Diverging regulation of pyruvate dehydrogenase kinase isoform gene expression in cultured human muscle cells.

Abbot EL, McCormack JG, Reynet C, Hassall DG, Buchan KW, Yeaman SJ.

FEBS J. 2005 Jun;272(12):3004-14.PMID: 15955060 [PubMed - indexed for MEDLINE]Related articlesFree article

A dominant-negative p38 MAPK mutant and novel selective inhibitors of p38 MAPK reduce insulin-stimulated glucose uptake in 3T3-L1 adipocytes without affecting GLUT4 translocation.

Somwar R, Koterski S, Sweeney G, Sciotti R, Djuric S, Berg C, Trevillyan J, Scherer PE, Rondinone CM, Klip A.

J Biol Chem. 2002 Dec 27;277(52):50386-95. Epub 2002 Oct 21.PMID: 12393894 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of troglitazone on cellular differentiation, insulin signaling, and glucose metabolism in cultured human skeletal muscle cells.

Kausch C, Krützfeldt J, Witke A, Rettig A, Bachmann O, Rett K, Matthaei S, Machicao F, Häring HU, Stumvoll M.

Biochem Biophys Res Commun. 2001 Jan 26;280(3):664-74.PMID: 11162573 [PubMed - indexed for MEDLINE]Related articles

Enhanced insulin-stimulated glycogen synthesis in response to insulin, metformin or rosiglitazone is associated with increased mRNA expression of GLUT4 and peroxisomal proliferator activator receptor gamma co-activator 1.

Al-Khalili L, Forsgren M, Kannisto K, Zierath JR, Lönnqvist F, Krook A.

Diabetologia. 2005 Jun;48(6):1173-9. Epub 2005 Apr 30.PMID: 15864539 [PubMed - indexed for MEDLINE]Related articles