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    Results: 1 to 20 of 196

    1.

    Metformin prevents glucose-induced protein kinase C-beta2 activation in human umbilical vein endothelial cells through an antioxidant mechanism.

    Gallo A, Ceolotto G, Pinton P, Iori E, Murphy E, Rutter GA, Rizzuto R, Semplicini A, Avogaro A.

    Diabetes. 2005 Apr;54(4):1123-31.PMID: 15793252 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Metformin reduces angiotensin-mediated intracellular production of reactive oxygen species in endothelial cells through the inhibition of protein kinase C.

    Mahrouf M, Ouslimani N, Peynet J, Djelidi R, Couturier M, Therond P, Legrand A, Beaudeux JL.

    Biochem Pharmacol. 2006 Jul 14;72(2):176-83. Epub 2006 May 4.PMID: 16730666 [PubMed - indexed for MEDLINE]Related articles

    3.

    Requirement of aldose reductase for the hyperglycemic activation of protein kinase C and formation of diacylglycerol in vascular smooth muscle cells.

    Ramana KV, Friedrich B, Tammali R, West MB, Bhatnagar A, Srivastava SK.

    Diabetes. 2005 Mar;54(3):818-29.PMID: 15734861 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Protein kinase C activity is acutely regulated by plasma glucose concentration in human monocytes in vivo.

    Ceolotto G, Gallo A, Miola M, Sartori M, Trevisan R, Del Prato S, Semplicini A, Avogaro A.

    Diabetes. 1999 Jun;48(6):1316-22.PMID: 10342822 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Metformin prevents high-glucose-induced endothelial cell death through a mitochondrial permeability transition-dependent process.

    Detaille D, Guigas B, Chauvin C, Batandier C, Fontaine E, Wiernsperger N, Leverve X.

    Diabetes. 2005 Jul;54(7):2179-87.PMID: 15983220 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Metformin inhibits proinflammatory responses and nuclear factor-kappaB in human vascular wall cells.

    Isoda K, Young JL, Zirlik A, MacFarlane LA, Tsuboi N, Gerdes N, Schönbeck U, Libby P.

    Arterioscler Thromb Vasc Biol. 2006 Mar;26(3):611-7. Epub 2005 Dec 29.PMID: 16385087 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    High glucose induces antioxidant enzymes in human endothelial cells in culture. Evidence linking hyperglycemia and oxidative stress.

    Ceriello A, dello Russo P, Amstad P, Cerutti P.

    Diabetes. 1996 Apr;45(4):471-7.PMID: 8603769 [PubMed - indexed for MEDLINE]Related articles

    8.

    Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells.

    Kukidome D, Nishikawa T, Sonoda K, Imoto K, Fujisawa K, Yano M, Motoshima H, Taguchi T, Matsumura T, Araki E.

    Diabetes. 2006 Jan;55(1):120-7.PMID: 16380484 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Introduction of apoptosis by high proinsulin and glucose in cultured human umbilical vein endothelial cells is mediated by reactive oxygen species.

    Du XL, Sui GZ, Stockklauser-Färber K, Weiss J, Zink S, Schwippert B, Wu QX, Tschöpe D, Rösen P.

    Diabetologia. 1998 Mar;41(3):249-56.PMID: 9541163 [PubMed - indexed for MEDLINE]Related articles

    10.

    Metformin suppresses high glucose-induced poly(adenosine diphosphate-ribose) polymerase overactivation in aortic endothelial cells.

    Mahrouf-Yorgov M, Marie N, Borderie D, Djelidi R, Bonnefont-Rousselot D, Legrand A, Beaudeux JL, Peynet J.

    Metabolism. 2009 Apr;58(4):525-33.PMID: 19303974 [PubMed - indexed for MEDLINE]Related articles

    11.

    [In vitro study of the effects of pioglitazone on endothelial cell functions of human umbilical vein and the mechanisms involved]

    Tong NW, Wan Q, Liu XJ, Wu H.

    Sichuan Da Xue Xue Bao Yi Xue Ban. 2005 Jul;36(4):525-8. Chinese. PMID: 16078579 [PubMed - indexed for MEDLINE]Related articles

    12.

    Increased expression of endothelin-converting enzyme-1c isoform in response to high glucose levels in endothelial cells.

    Keynan S, Khamaisi M, Dahan R, Barnes K, Jackson CD, Turner AJ, Raz I.

    J Vasc Res. 2004 Mar-Apr;41(2):131-40. Epub 2004 Feb 27.PMID: 15010576 [PubMed - indexed for MEDLINE]Related articles

    13.

    Evaluation of gliclazide ability to attenuate the hyperglycaemic 'memory' induced by high glucose in isolated human endothelial cells.

    Corgnali M, Piconi L, Ihnat M, Ceriello A.

    Diabetes Metab Res Rev. 2008 May-Jun;24(4):301-9.PMID: 18088078 [PubMed - indexed for MEDLINE]Related articles

    14.

    Generation of reactive oxygen species by endothelial and smooth muscle cells: influence of hyperglycemia and metformin.

    Bellin C, de Wiza DH, Wiernsperger NF, Rösen P.

    Horm Metab Res. 2006 Nov;38(11):732-9.PMID: 17111300 [PubMed - indexed for MEDLINE]Related articles

    15.

    Induction of endothelin-1 expression by glucose: an effect of protein kinase C activation.

    Park JY, Takahara N, Gabriele A, Chou E, Naruse K, Suzuma K, Yamauchi T, Ha SW, Meier M, Rhodes CJ, King GL.

    Diabetes. 2000 Jul;49(7):1239-48.PMID: 10909984 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Rosiglitazone reduces glucose-induced oxidative stress mediated by NAD(P)H oxidase via AMPK-dependent mechanism.

    Ceolotto G, Gallo A, Papparella I, Franco L, Murphy E, Iori E, Pagnin E, Fadini GP, Albiero M, Semplicini A, Avogaro A.

    Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2627-33. Epub 2007 Oct 4.PMID: 17916771 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Coenzyme Q10 prevents high glucose-induced oxidative stress in human umbilical vein endothelial cells.

    Tsuneki H, Sekizaki N, Suzuki T, Kobayashi S, Wada T, Okamoto T, Kimura I, Sasaoka T.

    Eur J Pharmacol. 2007 Jul 2;566(1-3):1-10. Epub 2007 Mar 19.PMID: 17434478 [PubMed - indexed for MEDLINE]Related articles

    18.

    Reduction of high glucose and phorbol-myristate-acetate-induced endothelial cell permeability by protein kinase C inhibitors LY379196 and hypocrellin A.

    Dang L, Seale JP, Qu X.

    Biochem Pharmacol. 2004 Mar 1;67(5):855-64.PMID: 15104238 [PubMed - indexed for MEDLINE]Related articles

    19.

    Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase.

    Davis BJ, Xie Z, Viollet B, Zou MH.

    Diabetes. 2006 Feb;55(2):496-505.PMID: 16443786 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Protein kinase C-beta mediates lipoprotein-induced generation of PAI-1 from vascular endothelial cells.

    Ren S, Shatadal S, Shen GX.

    Am J Physiol Endocrinol Metab. 2000 Apr;278(4):E656-62.PMID: 10751199 [PubMed - indexed for MEDLINE]Related articlesFree article

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