PubMed

Pancreatic beta-cell failure and diabetes in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPK.

Ladiges WC, Knoblaugh SE, Morton JF, Korth MJ, Sopher BL, Baskin CR, MacAuley A, Goodman AG, LeBoeuf RC, Katze MG.

Diabetes. 2005 Apr;54(4):1074-81.PMID: 15793246 [PubMed - indexed for MEDLINE]Related articlesFree article

Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.

Yan W, Frank CL, Korth MJ, Sopher BL, Novoa I, Ron D, Katze MG.

Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):15920-5. Epub 2002 Nov 22.PMID: 12446838 [PubMed - indexed for MEDLINE]Related articlesFree article

P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling.

van Huizen R, Martindale JL, Gorospe M, Holbrook NJ.

J Biol Chem. 2003 May 2;278(18):15558-64. Epub 2003 Feb 24.PMID: 12601012 [PubMed - indexed for MEDLINE]Related articlesFree article

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes.

Laybutt DR, Preston AM, Akerfeldt MC, Kench JG, Busch AK, Biankin AV, Biden TJ.

Diabetologia. 2007 Apr;50(4):752-63. Epub 2007 Feb 1.PMID: 17268797 [PubMed - indexed for MEDLINE]Related articles

P58(IPK) inhibition of endoplasmic reticulum stress in human retinal capillary endothelial cells in vitro.

Li B, Li D, Li GG, Wang HW, Yu AX.

Mol Vis. 2008 Jul 13;14:1122-8.PMID: 18568130 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of double-stranded RNA- and tumor necrosis factor alpha-mediated apoptosis by tetratricopeptide repeat protein and cochaperone P58(IPK).

Tang NM, Korth MJ, Gale M Jr, Wambach M, Der SD, Bandyopadhyay SK, Williams BR, Katze MG.

Mol Cell Biol. 1999 Jul;19(7):4757-65.PMID: 10373525 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of endoplasmic reticulum stress pathway on pancreatic beta-cells and diabetes mellitus.

Araki E, Oyadomari S, Mori M.

Exp Biol Med (Maywood). 2003 Nov;228(10):1213-7. Review.PMID: 14610263 [PubMed - indexed for MEDLINE]Related articlesFree article

Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload.

Oyadomari S, Yun C, Fisher EA, Kreglinger N, Kreibich G, Oyadomari M, Harding HP, Goodman AG, Harant H, Garrison JL, Taunton J, Katze MG, Ron D.

Cell. 2006 Aug 25;126(4):727-39. Erratum in: Cell. 2006 Dec 16;127(6):1284. PMID: 16923392 [PubMed - indexed for MEDLINE]Related articles

Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes.

Oyadomari S, Koizumi A, Takeda K, Gotoh T, Akira S, Araki E, Mori M.

J Clin Invest. 2002 Feb;109(4):525-32.PMID: 11854325 [PubMed - indexed for MEDLINE]Related articlesFree article

P52rIPK regulates the molecular cochaperone P58IPK to mediate control of the RNA-dependent protein kinase in response to cytoplasmic stress.

Gale M Jr, Blakely CM, Darveau A, Romano PR, Korth MJ, Katze MG.

Biochemistry. 2002 Oct 1;41(39):11878-87.PMID: 12269832 [PubMed - indexed for MEDLINE]Related articles

The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.

Marchetti P, Bugliani M, Lupi R, Marselli L, Masini M, Boggi U, Filipponi F, Weir GC, Eizirik DL, Cnop M.

Diabetologia. 2007 Dec;50(12):2486-94. Epub 2007 Sep 30.PMID: 17906960 [PubMed - indexed for MEDLINE]Related articles

Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells.

Oyadomari S, Araki E, Mori M.

Apoptosis. 2002 Aug;7(4):335-45. Review.PMID: 12101393 [PubMed - indexed for MEDLINE]Related articles

WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells.

Yamada T, Ishihara H, Tamura A, Takahashi R, Yamaguchi S, Takei D, Tokita A, Satake C, Tashiro F, Katagiri H, Aburatani H, Miyazaki J, Oka Y.

Hum Mol Genet. 2006 May 15;15(10):1600-9. Epub 2006 Mar 28.PMID: 16571599 [PubMed - indexed for MEDLINE]Related articlesFree article

The role for endoplasmic reticulum stress in diabetes mellitus.

Eizirik DL, Cardozo AK, Cnop M.

Endocr Rev. 2008 Feb;29(1):42-61. Epub 2007 Nov 29. Review.PMID: 18048764 [PubMed - indexed for MEDLINE]Related articlesFree article

Down-regulation of the endoplasmic reticulum chaperone GRP78/BiP by vomitoxin (Deoxynivalenol).

Yang GH, Li S, Pestka JJ.

Toxicol Appl Pharmacol. 2000 Feb 1;162(3):207-17.PMID: 10652249 [PubMed - indexed for MEDLINE]Related articles

The role of p58IPK in protecting the stressed endoplasmic reticulum.

Rutkowski DT, Kang SW, Goodman AG, Garrison JL, Taunton J, Katze MG, Kaufman RJ, Hegde RS.

Mol Biol Cell. 2007 Sep;18(9):3681-91. Epub 2007 Jun 13.PMID: 17567950 [PubMed - indexed for MEDLINE]Related articlesFree article

The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-mediated mechanism.

Goodman AG, Smith JA, Balachandran S, Perwitasari O, Proll SC, Thomas MJ, Korth MJ, Barber GN, Schiff LA, Katze MG.

J Virol. 2007 Mar;81(5):2221-30. Epub 2006 Dec 13.PMID: 17166899 [PubMed - indexed for MEDLINE]Related articlesFree article

ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress.

Yamaguchi S, Ishihara H, Yamada T, Tamura A, Usui M, Tominaga R, Munakata Y, Satake C, Katagiri H, Tashiro F, Aburatani H, Tsukiyama-Kohara K, Miyazaki J, Sonenberg N, Oka Y.

Cell Metab. 2008 Mar;7(3):269-76.PMID: 18316032 [PubMed - indexed for MEDLINE]Related articles

The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells.

Nozaki J, Kubota H, Yoshida H, Naitoh M, Goji J, Yoshinaga T, Mori K, Koizumi A, Nagata K.

Genes Cells. 2004 Mar;9(3):261-70.PMID: 15005713 [PubMed - indexed for MEDLINE]Related articles

Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cells.

Lai E, Bikopoulos G, Wheeler MB, Rozakis-Adcock M, Volchuk A.

Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E540-50. Epub 2008 Jan 15.PMID: 18198352 [PubMed - indexed for MEDLINE]Related articlesFree article