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The Estradiol-Dihydrotestosterone model of prostate cancer.

Friedman AE.

Theor Biol Med Model. 2005 Mar 18;2:10.PMID: 15777479 [PubMed - indexed for MEDLINE]Related articlesFree article

5alpha-androstane-3alpha,17beta-diol supports human prostate cancer cell survival and proliferation through androgen receptor-independent signaling pathways: implication of androgen-independent prostate cancer progression.

Yang Q, Titus MA, Fung KM, Lin HK.

J Cell Biochem. 2008 Aug 1;104(5):1612-24.PMID: 18320593 [PubMed - indexed for MEDLINE]Related articles

Development of hormone-dependent prostate cancer models for the evaluation of inhibitors of 17beta-hydroxysteroid dehydrogenase type 3.

Day JM, Tutill HJ, Foster PA, Bailey HV, Heaton WB, Sharland CM, Vicker N, Potter BV, Purohit A, Reed MJ.

Mol Cell Endocrinol. 2009 Mar 25;301(1-2):251-8. Epub 2008 Aug 22.PMID: 18786604 [PubMed - indexed for MEDLINE]Related articles

DHT and testosterone, but not DHEA or E2, differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells.

Le H, Arnold JT, McFann KK, Blackman MR.

Am J Physiol Endocrinol Metab. 2006 May;290(5):E952-60. Epub 2005 Dec 20.PMID: 16368782 [PubMed - indexed for MEDLINE]Related articlesFree article

17alpha-estradiol inhibits LAPC-4 prostatic tumor cell proliferation in cell cultures and tumor growth in xenograft animals.

Qiao Y, Zhang ZK, Cai LQ, Tan C, Imperato-McGinley JL, Zhu YS.

Prostate. 2007 Dec 1;67(16):1719-28.PMID: 17879940 [PubMed - indexed for MEDLINE]Related articles

Receptor isoform and ligand-specific modulation of dihydrotestosterone-induced prostate specific antigen gene expression and prostate tumor cell growth by estrogens.

Zhu YS, Cai LQ, Huang Y, Fish J, Wang L, Zhang ZK, Imperato-McGinley JL.

J Androl. 2005 Jul-Aug;26(4):500-8; discussion 509-10.PMID: 15955889 [PubMed - indexed for MEDLINE]Related articlesFree article

Dihydrotestosterone and estradiol-17beta mutually neutralize their inhibitory effects on human vascular smooth muscle cell growth in vitro.

Somjen D, Kohen F, Gayer B, Knoll E, Many A, Stern N.

J Steroid Biochem Mol Biol. 2009 Feb;113(3-5):171-6. Epub 2008 Dec 3.PMID: 19103289 [PubMed - indexed for MEDLINE]Related articles

Adenocarcinoma of prostate: role of 17beta-estradiol and 5alpha-dihydrotestosterone binding proteins.

Sidh SM, Young JD Jr, Karmi SA, Powder JR, Bashirelahi N.

Urology. 1979 Jun;13(6):597-603.PMID: 452193 [PubMed - indexed for MEDLINE]Related articles

Steroid hormones stimulate human prostate cancer progression and metastasis.

Ricke WA, Ishii K, Ricke EA, Simko J, Wang Y, Hayward SW, Cunha GR.

Int J Cancer. 2006 May 1;118(9):2123-31.PMID: 16331600 [PubMed - indexed for MEDLINE]Related articles

The androgen derivative 5alpha-androstane-3beta,17beta-diol inhibits prostate cancer cell migration through activation of the estrogen receptor beta subtype.

Guerini V, Sau D, Scaccianoce E, Rusmini P, Ciana P, Maggi A, Martini PG, Katzenellenbogen BS, Martini L, Motta M, Poletti A.

Cancer Res. 2005 Jun 15;65(12):5445-53.PMID: 15958594 [PubMed - indexed for MEDLINE]Related articlesFree article

The levels of 5alpha-dihydrotestosterone in follicular fluid in healthy and atretic ovine follicles.

Tetsuka M, Nancarrow CD.

Domest Anim Endocrinol. 2007 Oct;33(3):347-57. Epub 2006 Aug 22.PMID: 16962281 [PubMed - indexed for MEDLINE]Related articles

Distinct regulation by steroids of messenger RNAs for FSHR and CYP19A1 in bovine granulosa cells.

Luo W, Wiltbank MC.

Biol Reprod. 2006 Aug;75(2):217-25. Epub 2006 Apr 26.PMID: 16641147 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacologic basis for the enhanced efficacy of dutasteride against prostatic cancers.

Xu Y, Dalrymple SL, Becker RE, Denmeade SR, Isaacs JT.

Clin Cancer Res. 2006 Jul 1;12(13):4072-9.PMID: 16818707 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of RIZ1 protein (Retinoblastoma-interacting zinc-finger protein 1) in prostate cancer epithelial cells changes with cancer grade progression and is modulated in vitro by DHT and E2.

Rossi V, Staibano S, Abbondanza C, Pasquali D, De Rosa C, Mascolo M, Bellastella G, Visconti D, De Bellis A, Moncharmont B, De Rosa G, Puca GA, Bellastella A, Sinisi AA.

J Cell Physiol. 2009 Dec;221(3):771-7.PMID: 19746436 [PubMed - indexed for MEDLINE]Related articles

Androgen-induced Wnt signaling in preosteoblasts promotes the growth of MDA-PCa-2b human prostate cancer cells.

Liu XH, Kirschenbaum A, Yao S, Liu G, Aaronson SA, Levine AC.

Cancer Res. 2007 Jun 15;67(12):5747-53.PMID: 17575141 [PubMed - indexed for MEDLINE]Related articlesFree article

Hormonal regulation of renal multidrug resistance-associated proteins 3 and 4 (Mrp3 and Mrp4) in mice.

Maher JM, Cheng X, Tanaka Y, Scheffer GL, Klaassen CD.

Biochem Pharmacol. 2006 May 14;71(10):1470-8. Epub 2006 Mar 9.PMID: 16529719 [PubMed - indexed for MEDLINE]Related articles

Can a single model explain both breast cancer and prostate cancer?

Friedman AE.

Theor Biol Med Model. 2007 Aug 1;4:28. Review.PMID: 17678531 [PubMed - indexed for MEDLINE]Related articlesFree article

Atlas of dihydrotestosterone actions on the transcriptome of prostate in vivo.

Ma C, Yoshioka M, Boivin A, Gan L, Takase Y, Labrie F, St-Amand J.

Prostate. 2009 Feb 15;69(3):293-316.PMID: 19023869 [PubMed - indexed for MEDLINE]Related articles

Understanding the epidemiology, natural history, and key pathways involved in prostate cancer.

Crawford ED.

Urology. 2009 May;73(5 Suppl):S4-10. Review.PMID: 19375626 [PubMed - indexed for MEDLINE]Related articles

Regucalcin is under-expressed in human breast and prostate cancers: Effect of sex steroid hormones.

Maia C, Santos C, Schmitt F, Socorro S.

J Cell Biochem. 2009 Jul 1;107(4):667-76.PMID: 19347872 [PubMed - indexed for MEDLINE]Related articles